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Protein

Coatomer subunit gamma

Gene

copg2

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Coatomer subunit gammaUniRule annotation
Gene namesi
Name:copg2Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiH2UTW1

Interactioni

Subunit structurei

Oligomeric complex.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 538Adaptin_NInterPro annotationAdd BLAST514
Domaini612 – 758COP-gamma_platfInterPro annotationAdd BLAST147
Domaini760 – 872Coatomer_g_CplaInterPro annotationAdd BLAST113

Sequence similaritiesi

Belongs to the COPG family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
GeneTreeiENSGT00390000016313
InParanoidiH2UTW1
KOiK17267
OMAiISFLGMQ
OrthoDBiEOG091G0HWQ
TreeFamiTF300324

Family and domain databases

Gene3Di1.25.10.10, 2 hits
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

Sequencei

Sequence statusi: Complete.

H2UTW1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKKFDKKDE ESGSGSNPFQ NLEKSAVLQE ARIFNETPIN PRRCLHILTK
60 70 80 90 100
IIYLLNQGEH FGTTEATEAF FAMTRLFQSN DQTLRRMCYL TIKEMANISE
110 120 130 140 150
DVIIVTSSLT KDMTGKEDVY RGPAIRALCR ITDTTMLQAI ERYMKQAIVD
160 170 180 190 200
KVPSVSSSAL VSSLHMVKMS YDVVKRWVNE AQEAASSDNI MVQYHALGLL
210 220 230 240 250
YHLRKNDRLA VTKMLNKFTK SGLKSPFAYC MLIRIASKLL DETEAGHDSP
260 270 280 290 300
LFDFIESCLR NKNEMVVYEA ASAIVHMPNC TARELAPAVS VLQLFCSSPK
310 320 330 340 350
AALRYAAVRT LNKVAMKHPS AVTACNLDLE NLITDSNRSI ATLAITTLLK
360 370 380 390 400
TGSESSVDRL MKQISSFVSE ISDEFKVVVV QAISALCQKY PRKHSVMMNF
410 420 430 440 450
LSNMLRDDGG FEYKRAIVDC IISIIEENPE SKETGLAHLC EFIEDCEHTV
460 470 480 490 500
LATKILHLLG KEGPRTPQPS KYIRFIFNRV VLESEAVRAA AVSALAKFGA
510 520 530 540 550
QNDDLLPSVL VLMQRCMMDS DDEVRDRATF YMNVLQQKQK ALNAAYIFNG
560 570 580 590 600
LSVSIPGLEK SLHQYTLEPS EKPFDMKSVP LATTPITEQK TEIAPAATSK
610 620 630 640 650
LPEKLAPSRQ DIYQEQLAAI PEFQGLGPLF KSSDPVQLTE AETEYVVRCI
660 670 680 690 700
KHTFARHMVF QFDCTNTLND QLLQKVLVQM EPSEAYEVIH YIPAPSLPYS
710 720 730 740 750
QPGSCYSLVR LPDDDPTAVS CTFSCTMKYL VRDCDPNTGE PDDDGYDDEY
760 770 780 790 800
VLEDLEVTVA DHIQKVLKPN FGAAWEEVGD EFEKEETFAL ASVRTLDEAV
810 820 830 840 850
GNIISFLGMQ PCERSDKVPE NKNSHVLFLA GVFRGGHDVL VRARLALADG
860 870
VTMQVTVRSS EETVVDVILA SVG
Length:873
Mass (Da):97,472
Last modified:March 21, 2012 - v1
Checksum:i619E0CCDA3A67F83
GO

Sequence databases

RefSeqiXP_003972850.1, XM_003972801.2

Genome annotation databases

EnsembliENSTRUT00000040527; ENSTRUP00000040385; ENSTRUG00000015806
GeneIDi101065921
KEGGitru:101065921

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_003972850.1, XM_003972801.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiH2UTW1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTRUT00000040527; ENSTRUP00000040385; ENSTRUG00000015806
GeneIDi101065921
KEGGitru:101065921

Organism-specific databases

CTDi26958

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
GeneTreeiENSGT00390000016313
InParanoidiH2UTW1
KOiK17267
OMAiISFLGMQ
OrthoDBiEOG091G0HWQ
TreeFamiTF300324

Family and domain databases

Gene3Di1.25.10.10, 2 hits
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH2UTW1_TAKRU
AccessioniPrimary (citable) accession number: H2UTW1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: November 7, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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