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Protein
Submitted name:

Bone morphogenetic protein 4

Gene

bmp4

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGrowth factorUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Bone morphogenetic protein 4Imported
Gene namesi
Name:bmp4Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500357454020 – 402Sequence analysisAdd BLAST383

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000037164

Structurei

3D structure databases

ProteinModelPortaliH2UJP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini286 – 402TGF_BETA_2InterPro annotationAdd BLAST117

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3900 Eukaryota
ENOG410XT8Z LUCA
GeneTreeiENSGT00760000118883
InParanoidiH2UJP3
KOiK04662
OMAiQGFHRIN
OrthoDBiEOG091G0K7Z
TreeFamiTF351789

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR001839 TGF-b_C
IPR001111 TGF-b_propeptide
IPR015615 TGF-beta-rel
IPR017948 TGFb_CS
PANTHERiPTHR11848 PTHR11848, 1 hit
PfamiView protein in Pfam
PF00019 TGF_beta, 1 hit
PF00688 TGFb_propeptide, 1 hit
SMARTiView protein in SMART
SM00204 TGFB, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS00250 TGF_BETA_1, 1 hit
PS51362 TGF_BETA_2, 1 hit

Sequencei

Sequence statusi: Complete.

H2UJP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPGNRMLMV ILICQVLLGE NNHASLIPEE GKKKVPGLQG RSATQSHELL
60 70 80 90 100
RDFEATLLHM FGLKRRPRPS RSTAVPQYLL DLYRLQSGEA EEAEGQDIAF
110 120 130 140 150
EYPERAASRA NTVRGFHHEE HMERVHELGA AESTSLRFLF NLSSIPEDEL
160 170 180 190 200
LSSAELRLYR HQINEDNVTL SADHGLHRIN VYEVLKLPRQ GQLITQLLDT
210 220 230 240 250
RLVRHNTSSW ESFDVSPAVL RWTREGLPNY GLAVEVLHLN QTPRHQGRHV
260 270 280 290 300
RVSRSLHQEP GEDWEQIRPL LVTFSHDGKG HPLIRRSKRS PKQRGRKRNR
310 320 330 340 350
NCRRHSLYVD FSDVGWNDWI VAPPGYQAYY CHGDCPFPLA DHLNSTNHAI
360 370 380 390 400
VQTLVNSVNS NIPKACCVPT ELSAISMLYL DEHDKVVLKN YNEMVVEGCG

CR
Length:402
Mass (Da):45,937
Last modified:March 21, 2012 - v1
Checksum:i2656FAF40EE51285
GO

Sequence databases

RefSeqiXP_003962570.1, XM_003962521.2

Genome annotation databases

EnsembliENSTRUT00000037298; ENSTRUP00000037164; ENSTRUG00000014535
GeneIDi101061931
KEGGitru:101061931

Similar proteinsi

Entry informationi

Entry nameiH2UJP3_TAKRU
AccessioniPrimary (citable) accession number: H2UJP3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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