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Protein
Submitted name:

Erythropoietin receptor

Gene

LOC101071352

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Erythropoietin receptorImported
Gene namesi
Name:LOC101071352Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500357313524 – 533Sequence analysisAdd BLAST510

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi48 ↔ 58UniRule annotation
Disulfide bondi87 ↔ 103UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000021404

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini140 – 238Fibronectin type-IIIInterPro annotationAdd BLAST99

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili408 – 428Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IFGH Eukaryota
ENOG4111PGS LUCA
GeneTreeiENSGT00920000149107
InParanoidiH2T9R4
KOiK05079
OMAiKDFTCFW
OrthoDBiEOG091G0AK8
TreeFamiTF336573

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR009167 Erythropoietin_rcpt
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR015152 Growth/epo_recpt_lig-bind
IPR013783 Ig-like_fold
IPR003528 Long_hematopoietin_rcpt_CS
PANTHERiPTHR23037:SF28 PTHR23037:SF28, 1 hit
PfamiView protein in Pfam
PF09067 EpoR_lig-bind, 1 hit
PF00041 fn3, 1 hit
PIRSFiPIRSF001959 EPO_receptor, 2 hits
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SUPFAMiSSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit
PS01352 HEMATOPO_REC_L_F1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

H2T9R4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MITHHLNQLL LLTVIFSATQ TSASVQGARD FSKKVSIMLK EDPKTPKCFA
60 70 80 90 100
EGRKDFTCFW EEDEERAESL DQYSFKYTYQ NENSSRCPLR SIPAAHGKRL
110 120 130 140 150
FICHLNQPKM FVQMDMQVHR KGMLIYNRSL LVEMVFLLDP PANVTVTSTT
160 170 180 190 200
KQGQLNVTWV PPPLKYMDDS MVYEVSYSTV DSHMWQVEMV QASSELILRG
210 220 230 240 250
LQPGTKYKVR VRVKLDGISY SGYWSAWSES VLIETLPAEL DPLILSLVLI
260 270 280 290 300
IFFVLIGLFF TTLMSHRRYL VKKIWPKIPT PDSKFHGLFT IYGGEFQLWL
310 320 330 340 350
EQTIGLWVIP VFFNSEELSS SLEVLSELYN CPSRSSQLLT KDTNFLATHN
360 370 380 390 400
CVMNSMVERE NCEGAHSTLP EDWKTTTNNE MPMDSWRAAQ HNAVPCSKSS
410 420 430 440 450
FMEAQDAYVT LSTNNHREEE NLDNILEETL PLETNFASRK QICESHSDLG
460 470 480 490 500
SMQQSSGLSH LSSQSSFEYP NYAWMSKVYT YMAAVDSGVS VDYSPMHRVD
510 520 530
AIGKMIHTNE YKNGIDAQKR PFLVKTNPVH DES
Length:533
Mass (Da):60,953
Last modified:March 21, 2012 - v1
Checksum:i07C44E4D29B5382A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H2T9R5H2T9R5_TAKRU
Erythropoietin receptor
LOC101071352
461Annotation score:

Sequence databases

RefSeqiXP_003966434.1, XM_003966385.2

Genome annotation databases

EnsembliENSTRUT00000021492; ENSTRUP00000021404; ENSTRUG00000008544
GeneIDi101071352
KEGGitru:101071352

Similar proteinsi

Entry informationi

Entry nameiH2T9R4_TAKRU
AccessioniPrimary (citable) accession number: H2T9R4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: June 20, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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