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Protein
Submitted name:

BRCA1 interacting protein C-terminal helicase 1

Gene
N/A
Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1 interacting protein C-terminal helicase 1Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000019270

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 435Helicase ATP-bindingInterPro annotationAdd BLAST425

Phylogenomic databases

eggNOGiKOG1132 Eukaryota
COG1199 LUCA
GeneTreeiENSGT00530000063199
InParanoidiH2T3N2
OMAiTNNDMNQ
OrthoDBiEOG091G00LK
TreeFamiTF329449

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 7 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

H2T3N2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPASPLEYTI GGVKIQFPRK AYPSQLAMMN SIIRGLNTGQ HCLLESPTGS
60 70 80 90 100
GKSLALLCST LGWQQAQYVC LSQSQRRCLG YSCRHTCCCR PDCVTLQRVN
110 120 130 140 150
PATSCSSSRT KYVAAGSSSR RPSSEGTQAK KPSLASRLSQ KFQVFRKSAP
160 170 180 190 200
EEDDDFQPDR KRLRTPEQKK KRWKLFCVVL QQEHADLKPS SAALIGLISS
210 220 230 240 250
FASIFSFSFD KAAGPCTQCS CASKDGAKDQ NSNRRVPKIF FGTRTHKQIT
260 270 280 290 300
QVAHELRRTV YSKVPMTILS SRDHTCVNPE VAPHSKRNEL CKERLEAKDG
310 320 330 340 350
RSCRYYHGVQ KMGEQYLLQQ VHGVSEAWDI EDLVSLGKRL RSCSYFAARE
360 370 380 390 400
LMAEAVIIFC PYNYLLDPLI RESMDINLSG QILVLDEAHN IEDCARESAS
410 420 430 440 450
FTVNYDSLLA SRDELESMVK NKIREAKHEP LQNFCYSLIN WIQESQSLMS
460 470 480 490 500
ERGYESASKV WSGRDIVGIF HTLGITDATF NMLKANLAAV LEKEERLGFV
510 520 530 540 550
NGKEDVVQIP TISSATSAVL KGLFMVLDYL FRDKCRFAED YRVALQRSYA
560 570 580 590 600
WTNQVPPDAP DAQGFFVRPR QRQRQSIRVK AEMLTLSFWC LNPAVAFSDL
610 620 630 640 650
SNSLKSIVLT SGTLSPMGSF SSELGVKFSI QLEANHVINK SQVWVGTVGA
660 670 680 690 700
GPHGRKLCAT FQHAETYTFQ DEVGALLLHV CQVMAKGVLC FLPSYKMLDK
710 720 730 740 750
LRDRWSNTGL WEKLEQQKTV ITEPRGGGKG DFDELLQTYY EAIKGCQERD
760 770 780 790 800
GALLIAVCRG KVSEGLDFTD DNARAVVTIG IPFPNIKDLQ VELKMKYNDQ
810 820 830 840 850
HAKSRGLLSG HRWYEIQAYR ALNQALGRCI RHRNDWGALI LVDDRYKNNP
860 870 880 890
NKYITGLSKW VRQLVQHHDT FSNAMQSLGA FSREQQKVAL IPADARTS
Length:898
Mass (Da):100,998
Last modified:March 21, 2012 - v1
Checksum:i5911656A7A8D6382
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H2T3N4H2T3N4_TAKRU
BRCA1 interacting protein C-termina...
813Annotation score:
H2T3N3H2T3N3_TAKRU
BRCA1 interacting protein C-termina...
887Annotation score:
H2T3N5H2T3N5_TAKRU
BRCA1 interacting protein C-termina...
896Annotation score:

Genome annotation databases

EnsembliENSTRUT00000019348; ENSTRUP00000019270; ENSTRUG00000007748

Similar proteinsi

Entry informationi

Entry nameiH2T3N2_TAKRU
AccessioniPrimary (citable) accession number: H2T3N2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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