UniProtKB - H2RRN6 (H2RRN6_TAKRU)
Protein
BHLH domain-containing protein
Gene
myog
Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Functioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
GO - Biological processi
- myoblast differentiation involved in skeletal muscle regeneration Source: Ensembl
- myoblast proliferation involved in skeletal muscle regeneration Source: Ensembl
- positive regulation of myoblast fusion Source: Ensembl
- regulation of transcription, DNA-templated Source: InterPro
- response to activity Source: Ensembl
- skeletal muscle tissue development Source: Ensembl
Keywordsi
Molecular function | Developmental proteinARBA annotation, DNA-bindingARBA annotation |
Biological process | DifferentiationARBA annotation, MyogenesisARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: BHLH domain-containing proteinInterPro annotation |
Gene namesi | Name:myogImported |
Organismi | Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)Imported |
Taxonomic identifieri | 31033 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Eupercaria › Tetraodontiformes › Tetradontoidea › Tetraodontidae › Takifugu |
Proteomesi |
|
Subcellular locationi
Keywords - Cellular componenti
NucleusARBA annotationInteractioni
Subunit structurei
Efficient DNA binding requires dimerization with another bHLH protein.
ARBA annotationGO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 31033.ENSTRUP00000002802 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 98 – 149 | BHLHInterPro annotationAdd BLAST | 52 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 163 – 205 | DisorderedSequence analysisAdd BLAST | 43 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG3960, Eukaryota |
GeneTreei | ENSGT00950000182959 |
HOGENOMi | CLU_100258_0_0_1 |
InParanoidi | H2RRN6 |
OrthoDBi | 1471470at2759 |
TreeFami | TF316344 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR002546, MyoD_N IPR039704, Myogenic_factor |
PANTHERi | PTHR11534, PTHR11534, 1 hit |
Pfami | View protein in Pfam PF01586, Basic, 1 hit PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00520, BASIC, 1 hit SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
H2RRN6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MELFETNPYF FPDQRFYEGG DTYFPSRLPG SYDQGTYQDR NTMMGLCGSL
60 70 80 90 100
SGGVDVGVTG TEDKASPSSL SPHSEPHCPG QCLPWACKLC KRKTVTMDRR
110 120 130 140 150
RAATLREKRR LKKVNEAFDA LKRSTLMNPN QRLPKVEILR SAIQYIEKLQ
160 170 180 190 200
ALVSSLNQQD TETGQQGLHF RTSAVQPRVS SSSEPSSGST CCSSPEWSST
210 220 230 240 250
PDQCTQSYSS EDLLSAADSP DQGSMRTLTA IVDSISAADA AVAFSMDIPK
Sequence databases
RefSeqi | XP_003973654.1, XM_003973605.2 |
Genome annotation databases
Ensembli | ENSTRUT00000002818; ENSTRUP00000002802; ENSTRUG00000001200 |
GeneIDi | 446037 |
KEGGi | tru:446037 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003973654.1, XM_003973605.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 31033.ENSTRUP00000002802 |
Genome annotation databases
Ensembli | ENSTRUT00000002818; ENSTRUP00000002802; ENSTRUG00000001200 |
GeneIDi | 446037 |
KEGGi | tru:446037 |
Organism-specific databases
CTDi | 4656 |
Phylogenomic databases
eggNOGi | KOG3960, Eukaryota |
GeneTreei | ENSGT00950000182959 |
HOGENOMi | CLU_100258_0_0_1 |
InParanoidi | H2RRN6 |
OrthoDBi | 1471470at2759 |
TreeFami | TF316344 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR002546, MyoD_N IPR039704, Myogenic_factor |
PANTHERi | PTHR11534, PTHR11534, 1 hit |
Pfami | View protein in Pfam PF01586, Basic, 1 hit PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00520, BASIC, 1 hit SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H2RRN6_TAKRU | |
Accessioni | H2RRN6Primary (citable) accession number: H2RRN6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 21, 2012 |
Last sequence update: | December 5, 2018 | |
Last modified: | December 2, 2020 | |
This is version 55 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |