UniProtKB - H2R7P3 (H2R7P3_PANTR)
Protein
Submitted name:
Forkhead box F2
Gene
FOXF2
Organism
Pan troglodytes (Chimpanzee)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 97 – 191 | Fork-headPROSITE-ProRule annotationAdd BLAST | 95 |
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- transcription factor binding Source: Ensembl
GO - Biological processi
- animal organ morphogenesis Source: GO_Central
- embryonic camera-type eye morphogenesis Source: Ensembl
- embryonic digestive tract development Source: Ensembl
- establishment of planar polarity of embryonic epithelium Source: Ensembl
- extracellular matrix organization Source: Ensembl
- genitalia development Source: Ensembl
- negative regulation of transcription, DNA-templated Source: Ensembl
- regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
- regulation of protein polyubiquitination Source: Ensembl
- regulation of transcription by RNA polymerase II Source: GO_Central
- roof of mouth development Source: Ensembl
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Forkhead box F2Imported |
Gene namesi | Name:FOXF2Imported |
Organismi | Pan troglodytes (Chimpanzee)Imported |
Taxonomic identifieri | 9598 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pan |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:11081, FOXF2 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationARBA annotation
Nucleus
- nucleus Source: GO_Central
Other locations
- transcription regulator complex Source: Ensembl
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationExpressioni
Gene expression databases
Bgeei | ENSPTRG00000017662, Expressed in prefrontal cortex and 7 other tissues |
Interactioni
GO - Molecular functioni
- transcription factor binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 9598.ENSPTRP00000050645 |
Family & Domainsi
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000162527 |
HOGENOMi | CLU_039845_1_0_1 |
InParanoidi | H2R7P3 |
OMAi | TLACHSN |
OrthoDBi | 1120805at2759 |
TreeFami | TF351598 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
i Sequence
Sequence statusi: Complete.
H2R7P3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTEGGPPPA PLRRACSPVP GALQAALMSP PPAAAAAALE TTSSSSSSSS
60 70 80 90 100
ASCASSSSSS NSASAPSAAC KSTGGGGAGA GSGGAKKASS GLRRPEKPPY
110 120 130 140 150
SYIALIVMAI QSSPSKRLTL SEIYQFLQAR FPFFRGAYQG WKNSVRHNLS
160 170 180 190 200
LNECFIKLPK GLGRPGKGHY WTIDPASEFM FEEGSFRRRP RGFRRKCQAL
210 220 230 240 250
KPMYHRVVSG LGFGASLLPQ GFDFQAPPSA PLGCHSQGGY GGLDMMPAGY
260 270 280 290 300
DAGAGAPSHA HPHHHHHHHV PHMSPNPGST YMASCPVPAG PGGVGAAGGG
310 320 330 340 350
GGGGGGDYGP DSSSSPVPSS PAMASAIECH SPYTSPAAHW SSPGASPYLK
360 370 380 390 400
QPPALTPSSN PAASAGLHSS MSSYSLEQSY LHQNAREDLS VGLPRYQHHS
410 420 430 440
TPVCDRKDFV LNFNGISSFH PSASGSYYHH HHQSVCQDIK PCVM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AACZ04065990 Genomic DNA No translation available. |
RefSeqi | XP_001174677.2, XM_001174677.4 |
Genome annotation databases
Ensembli | ENSPTRT00000032651; ENSPTRP00000050645; ENSPTRG00000017662 |
GeneIDi | 750558 |
KEGGi | ptr:750558 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AACZ04065990 Genomic DNA No translation available. |
RefSeqi | XP_001174677.2, XM_001174677.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9598.ENSPTRP00000050645 |
Proteomic databases
PaxDbi | H2R7P3 |
Genome annotation databases
Ensembli | ENSPTRT00000032651; ENSPTRP00000050645; ENSPTRG00000017662 |
GeneIDi | 750558 |
KEGGi | ptr:750558 |
Organism-specific databases
CTDi | 2295 |
VGNCi | VGNC:11081, FOXF2 |
Phylogenomic databases
eggNOGi | KOG2294, Eukaryota |
GeneTreei | ENSGT00940000162527 |
HOGENOMi | CLU_039845_1_0_1 |
InParanoidi | H2R7P3 |
OMAi | TLACHSN |
OrthoDBi | 1120805at2759 |
TreeFami | TF351598 |
Gene expression databases
Bgeei | ENSPTRG00000017662, Expressed in prefrontal cortex and 7 other tissues |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H2R7P3_PANTR | |
Accessioni | H2R7P3Primary (citable) accession number: H2R7P3 Secondary accession number(s): A0A2J8MU48 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 21, 2012 |
Last sequence update: | February 28, 2018 | |
Last modified: | April 7, 2021 | |
This is version 64 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |