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Protein
Submitted name:

Rho guanine nucleotide exchange factor 40

Gene

ARHGEF40

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 40Imported
Gene namesi
Name:ARHGEF40Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 14

Organism-specific databases

VGNCiVGNC:3481 ARHGEF40

PTM / Processingi

Proteomic databases

PaxDbiH2R3U5

Expressioni

Gene expression databases

BgeeiENSPTRG00000006113

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000046092

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1085 – 1253DHInterPro annotationAdd BLAST169
Domaini1265 – 1372PHInterPro annotationAdd BLAST108

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0689 Eukaryota
ENOG410XSWY LUCA
GeneTreeiENSGT00920000149030
InParanoidiH2R3U5
OMAiVEEEAWD
OrthoDBiEOG091G016I
TreeFamiTF334329

Family and domain databases

Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

H2R3U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPEPVEDCV QSTLAALYPP FEATAPTLLG QVFQVVERTY REDALRYTLD
60 70 80 90 100
FLVPAKHLLA KVQQEACAQY SGFLFFHEGW PLCLHEQVVV QLAALPWQLL
110 120 130 140 150
RPGDFYLQVV PSAAQAPRLA LKCLAPGGGR VQEVPVPNEA CAYLFTPEWL
160 170 180 190 200
QGINKDRPTG RLSTCLLSAP SGIHRLPWAE LICPRFVHKE GLMVGHQPST
210 220 230 240 250
LPPELPSGPP GLPSPPLPEE ALGTRSPGDG HNAPVEGPEG EYVELLEVTL
260 270 280 290 300
PVRGSPTDAE GSPGLSRVRT VPTRKGAGGK GRHRRHRAWM HQKGLGPRDQ
310 320 330 340 350
DGARPPGEGS STGASPESPP GAEAVPEAAV FEVSEPPAEA VGEASESCPL
360 370 380 390 400
RPGELRGGGG GGQGAEGPPG TPRRTGKGNR RKKRAAGRGA LSRGGDSAPL
410 420 430 440 450
SPGDKEDASH QEALGNLPSP SEHKLPECHL VKEEYEGSGK PESEPKELKT
460 470 480 490 500
AGEKEPQPSE ACGPTEEGAG ERELEGPGLL CMAGHTGPEG LLSDTPTPPL
510 520 530 540 550
ETVQEGKGDN IPEEALAVSV SDHRDVAWDL MASGFLILTG GVDQSGRALL
560 570 580 590 600
TITPPCPPEE PPPSRDTLNT TLHYLHSLLR PDLQTLGLSV LLDLRQAPPL
610 620 630 640 650
PPALIPVLSQ LQDSGDPPLV QRLLILIHHD LPTELCGFQG AEVLSENDLK
660 670 680 690 700
RVAKPEELQW ELGGHRDPSP SHWVEIHQEV VRLCRLCQGV LGSVRQAIEE
710 720 730 740 750
LEGAAEPEEE EAVGMPKPLQ KVLADPRLTA LQRDGGAILM RLRSTPSSKL
760 770 780 790 800
EGQGPATLYQ EVDEAIHQLV RLSNLHVQQQ EQRQCLRRLQ QVLQWLSGPG
810 820 830 840 850
EEQLASFALP GDTLSALQET ELRFRAFSAE VQERLAQARE ALALEENATS
860 870 880 890 900
QKVLDIFEQR LEQVESGLHR ALRLQRFFQQ AHEWVDEGFA RLAGAGPGRE
910 920 930 940 950
AVLAALALRR APEPSAGTFQ EMRALALDLG SPAALREWGR CRARCQELER
960 970 980 990 1000
RIQQHLGEEA SPRGYRRRRA DSASSGGAQW GPRSPSPSLS SLLLPSSPGP
1010 1020 1030 1040 1050
WPAPSHCSLA PCGEDYEEEG PELAPEAEGR PPRAVLIRGL EVTSTEVVDR
1060 1070 1080 1090 1100
TCSPREHVLL GRAGGPDGPW GVGTPRMERK RSISAQQRLV SELIACEQDY
1110 1120 1130 1140 1150
VAALSEPVPP PGPELTPELR GTWAAALSAR ERLHSFHRTH FLRELQGCAT
1160 1170 1180 1190 1200
HPLRIGACFL RHGDQFSLYA QYVKHRHKLE NGLAALSPSS KGSMEAGPYL
1210 1220 1230 1240 1250
PRALQQPLEQ LTRYGRLLEE LLREAGPELS SERQALGAAV QLLREQEARG
1260 1270 1280 1290 1300
RDLLAVEAVR GCEIDLKEQG QLLHRDPFTV ICGRKKCLRH VFLFEHLLLF
1310 1320 1330 1340 1350
SKLKGPEGGS ETFVYKQAFK TADMGLTENI GDSGLCFELW FRRRRAREAY
1360 1370 1380 1390 1400
TLQATSPEIK LKWTSSIAQL LWRQAAHNKE LRVQQMVSMG IGNKPFLDIK
1410 1420 1430 1440 1450
ALGERTLSAL LTGRAARTRA SVAVSSFEHA GPSLPGLSPG ACSLPARVEE
1460 1470 1480 1490 1500
EAWDLDVKQI SLAPETLDSS GDVSPGPRNS PSLQPPHPGS STPTLASRGI
1510
LGLSRQSHAR ALSDPTTPL
Length:1,519
Mass (Da):164,845
Last modified:February 28, 2018 - v2
Checksum:i46D626476EE88BAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04052403 Genomic DNA No translation available.
RefSeqiXP_016781324.1, XM_016925835.1

Genome annotation databases

EnsembliENSPTRT00000011212; ENSPTRP00000046092; ENSPTRG00000006113
GeneIDi473328

Similar proteinsi

Entry informationi

Entry nameiH2R3U5_PANTR
AccessioniPrimary (citable) accession number: H2R3U5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: June 20, 2018
This is version 38 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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