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Protein
Submitted name:

RBPJ isoform 10

Gene

RBPJ

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
RBPJ isoform 10Imported
Submitted name:
Recombination signal binding protein for immunoglobulin kappa J regionImported
Gene namesi
Name:RBPJImported
ORF Names:CK820_G0007571Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 4

Organism-specific databases

VGNCiVGNC:675 RBPJ

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiH2R2Q6

Expressioni

Gene expression databases

BgeeiENSPTRG00000015968 Expressed in 6 organ(s), highest expression level in heart

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000044315

Structurei

3D structure databases

ProteinModelPortaliH2R2Q6
SMRiH2R2Q6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 163LAG1_DNAbindInterPro annotationAdd BLAST132
Domaini164 – 313BTDInterPro annotationAdd BLAST150

Phylogenomic databases

eggNOGiKOG3743 Eukaryota
ENOG410XV7K LUCA
GeneTreeiENSGT00390000005197
InParanoidiH2R2Q6
OMAiDMPHFGL
OrthoDBiEOG091G057S
TreeFamiTF314117

Family and domain databases

CDDicd01176 IPT_RBP-Jkappa, 1 hit
Gene3Di2.60.40.10, 1 hit
2.60.40.1450, 1 hit
InterProiView protein in InterPro
IPR015350 Beta-trefoil_DNA-bd_dom
IPR036358 BTD_sf
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR008967 p53-like_TF_DNA-bd
IPR015351 RBP-J/Cbf11/Cbf12_DNA-bd
IPR037095 RBP-J/Cbf11/Cbf12_DNA-bd_sf
IPR038007 RBP-Jkappa_IPT
PfamiView protein in Pfam
PF09270 BTD, 1 hit
PF09271 LAG1-DNAbind, 1 hit
SMARTiView protein in SMART
SM01268 BTD, 1 hit
SM01267 LAG1_DNAbind, 1 hit
SUPFAMiSSF110217 SSF110217, 1 hit
SSF49417 SSF49417, 1 hit
SSF81296 SSF81296, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H2R2Q6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGCRKFGER PPPKRLTREA MRNYLKERGD QTVLILHAKV AQKSYGNEKR
60 70 80 90 100
FFCPPPCVYL MGSGWKKKKE QMERDGCSEQ ESQPCAFIGI GNSDQEMQQL
110 120 130 140 150
NLEGKNYCTA KTLYISDSDK RKHFMLSVKM FYGNSDDIGV FLSKRIKVIS
160 170 180 190 200
KPSKKKQSLK NADLCIASGT KVALFNRLRS QTVSTRYLHV EGGNFHASSQ
210 220 230 240 250
QWGAFFIHLL DDDESEGEEF TVRDGYIHYG QTVKLVCSVT GMALPRLIIR
260 270 280 290 300
KVDKQTALLD ADDPVSQLHK CAFYLKDTER MYLCLSQERI IQFQATPCPK
310 320 330 340 350
EPNKEMINDG ASWTIISTDK AEYTFYEGMG PVLAPVTPVP VVESLQLNGG
360 370 380 390 400
GDVAMLELTG QNFTPNLRVW FGDVEAETMY RCGESMLCVV PDISAFREGW
410 420 430 440 450
RWVRQPVQVP VTLVRNDGII YSTSLTFTYT PEPGPRPHCS AAGAILRANS
460 470 480
SQVPPNESNT NSEGSYTNAS TNSTSVTSST ATVVS
Length:485
Mass (Da):54,146
Last modified:February 28, 2018 - v2
Checksum:iF0907B0A36490025
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2J8NVW7A0A2J8NVW7_PANTR
RBPJ isoform 12
RBPJ CK820_G0007571
500Annotation score:
A0A2J8NVV9A0A2J8NVV9_PANTR
RBPJ isoform 1
RBPJ CK820_G0007571
486Annotation score:
A0A2I3TEY3A0A2I3TEY3_PANTR
Recombination signal binding protei...
RBPJ
483Annotation score:
A0A2I3RF34A0A2I3RF34_PANTR
RBPJ isoform 9
RBPJ CK820_G0007571
382Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04033734 Genomic DNA No translation available.
AACZ04033735 Genomic DNA No translation available.
NBAG03000222 Genomic DNA Translation: PNI75909.1

Genome annotation databases

EnsembliENSPTRT00000048176; ENSPTRP00000044315; ENSPTRG00000015968

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04033734 Genomic DNA No translation available.
AACZ04033735 Genomic DNA No translation available.
NBAG03000222 Genomic DNA Translation: PNI75909.1

3D structure databases

ProteinModelPortaliH2R2Q6
SMRiH2R2Q6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000044315

Proteomic databases

PaxDbiH2R2Q6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000048176; ENSPTRP00000044315; ENSPTRG00000015968

Organism-specific databases

VGNCiVGNC:675 RBPJ

Phylogenomic databases

eggNOGiKOG3743 Eukaryota
ENOG410XV7K LUCA
GeneTreeiENSGT00390000005197
InParanoidiH2R2Q6
OMAiDMPHFGL
OrthoDBiEOG091G057S
TreeFamiTF314117

Gene expression databases

BgeeiENSPTRG00000015968 Expressed in 6 organ(s), highest expression level in heart

Family and domain databases

CDDicd01176 IPT_RBP-Jkappa, 1 hit
Gene3Di2.60.40.10, 1 hit
2.60.40.1450, 1 hit
InterProiView protein in InterPro
IPR015350 Beta-trefoil_DNA-bd_dom
IPR036358 BTD_sf
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR008967 p53-like_TF_DNA-bd
IPR015351 RBP-J/Cbf11/Cbf12_DNA-bd
IPR037095 RBP-J/Cbf11/Cbf12_DNA-bd_sf
IPR038007 RBP-Jkappa_IPT
PfamiView protein in Pfam
PF09270 BTD, 1 hit
PF09271 LAG1-DNAbind, 1 hit
SMARTiView protein in SMART
SM01268 BTD, 1 hit
SM01267 LAG1_DNAbind, 1 hit
SUPFAMiSSF110217 SSF110217, 1 hit
SSF49417 SSF49417, 1 hit
SSF81296 SSF81296, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH2R2Q6_PANTR
AccessioniPrimary (citable) accession number: H2R2Q6
Secondary accession number(s): A0A2J8NVX1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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