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Protein
Submitted name:

Chromodomain helicase DNA binding protein 4

Gene

CHD4

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Chromodomain helicase DNA binding protein 4Imported
Gene namesi
Name:CHD4Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 12

Organism-specific databases

VGNCiVGNC:51251 CHD4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiH2QZP6

Expressioni

Gene expression databases

BgeeiENSPTRG00000004580 Expressed in 6 organ(s), highest expression level in heart

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000039322

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini350 – 397PHD-typeInterPro annotationAdd BLAST48
Domaini429 – 476PHD-typeInterPro annotationAdd BLAST48
Domaini509 – 566ChromoInterPro annotationAdd BLAST58
Domaini602 – 637ChromoInterPro annotationAdd BLAST36
Domaini718 – 902Helicase ATP-bindingInterPro annotationAdd BLAST185
Domaini1034 – 1183Helicase C-terminalInterPro annotationAdd BLAST150

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1268 – 1288Sequence analysisAdd BLAST21
Coiled coili1636 – 1657Sequence analysisAdd BLAST22
Coiled coili1827 – 1847Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0383 Eukaryota
COG0553 LUCA
GeneTreeiENSGT00760000119067
InParanoidiH2QZP6
OMAiITIDMAI
OrthoDBiEOG091G00G4
TreeFamiTF106448

Family and domain databases

CDDicd00024 CHROMO, 2 hits
cd00079 HELICc, 1 hit
Gene3Di3.30.40.10, 2 hits
3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR012957 CHD_C2
IPR012958 CHD_N
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR009462 DUF1086
IPR009463 DUF1087
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF08074 CHDCT2, 1 hit
PF08073 CHDNT, 1 hit
PF00385 Chromo, 1 hit
PF06461 DUF1086, 1 hit
PF06465 DUF1087, 1 hit
PF00271 Helicase_C, 1 hit
PF00628 PHD, 2 hits
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 2 hits
SM00487 DEXDc, 1 hit
SM01146 DUF1086, 1 hit
SM01147 DUF1087, 1 hit
SM00490 HELICc, 1 hit
SM00249 PHD, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF54160 SSF54160, 3 hits
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50013 CHROMO_2, 2 hits
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS01359 ZF_PHD_1, 2 hits
PS50016 ZF_PHD_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

H2QZP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASGLGSPSP CSAGSEEEDM DALLNNSLPP PHPGNIFPKA CVCLSPSSPL
60 70 80 90 100
ALLQRMLLCR QLGDSSGEGP EFVEEEEEVA LRSDSEGSDY TPGKKKKKKL
110 120 130 140 150
GPKKEKKSKS KRKEEEEEDD DDDDSKEPKS SAQLLEDWGM EDIDHVFSEE
160 170 180 190 200
DYRTLTNYKA FSQFVRPLIA AKNPKIAVSK MMMVLGAKWR EFSTNNPFKG
210 220 230 240 250
SSGASVAAAA AAAVAVVESM VTATEVAPPP PPVEVPIRKA KTKEGKGPNA
260 270 280 290 300
RRKPKGSPRV PDAKKPKPKK VAPLKIKLGG FGSKRKRSSS EDDDLDVESD
310 320 330 340 350
FDDASINSYS VSDGSTSRSS RSRKKLRTTK KKKKGEEEVT AVDGYETDHQ
360 370 380 390 400
DYCEVCQQGG EIILCDTCPR AYHMVCLDPD MEKAPEGKWS CPHCEKEGIQ
410 420 430 440 450
WEAKEDNSEG EEILEEVGGD LEEEDDHHME FCRVCKDGGE LLCCDTCPSS
460 470 480 490 500
YHIHCLNPPL PEIPNGEWLC PRCTCPALKG KVQKILIWKW GQPPSPTPVP
510 520 530 540 550
RPPDADPNTP SPKPLEGRPE RQFFVKWQGM SYWHCSWVSE LQLELHCQVM
560 570 580 590 600
FRNYQRKNDM DEPPSGDFGG DEEKSRKRKN KDPKFAEMEE RFYRYGIKPE
610 620 630 640 650
WMMIHRILNH SVDKKGHVHY LIKWRDLPYD QASWESEDVE IQDYDLFKQS
660 670 680 690 700
YWNHRELMRG EEGRPGKKLK KVKLRKLERP PETPTVDPTV KYERQPEYLD
710 720 730 740 750
ATGGTLHPYQ MEGLNWLRFS WAQGTDTILA DEMGLGKTVQ TAVFLYSLYK
760 770 780 790 800
EGHSKGPFLV SAPLSTIINW EREFEMWAPD MYVVTYVGDK DSRAIIRENE
810 820 830 840 850
FSFEDNAIRG GKKASRMKKE ASVKFHVLLT SYELITIDMA ILGSIDWACL
860 870 880 890 900
IVDEAHRLKN NQSKFFRVLN GYSLQHKLLL TGTPLQNNLE ELFHLLNFLT
910 920 930 940 950
PERFHNLEGF LEEFADIAKE DQIKKLHDML GPHMLRRLKA DVFKNMPSKT
960 970 980 990 1000
ELIVRVELSP MQKKYYKYIL TRNFEALNAR GGGNQVSLLN VVMDLKKCCN
1010 1020 1030 1040 1050
HPYLFPVAAM EAPKMPNGMY DGSALIRASG KLLLLQKMLK NLKEGGHRVL
1060 1070 1080 1090 1100
IFSQMTKMLD LLEDFLEHEG YKYERIDGGI TGNMRQEAID RFNAPGAQQF
1110 1120 1130 1140 1150
CFLLSTRAGG LGINLATADT VIIYDSDWNP HNDIQAFSRA HRIGQNKKVM
1160 1170 1180 1190 1200
IYRFVTRASV EERITQVAKK KMMLTHLVVR PGLGSKTGSM SKQELDDILK
1210 1220 1230 1240 1250
FGTEELFKDE ATDGGGDNKE GEDSSVIHYD DKAIERLLDR NQDETEDTEL
1260 1270 1280 1290 1300
QGMNEYLSSF KVAQYVVREE EMGEEEEVER EIIKQEESVD PDYWEKLLRH
1310 1320 1330 1340 1350
HYEQQQEDLA RNLGKGKRIR KQVNYNDGSQ EDRDWQDDQS DNQSDYSVAS
1360 1370 1380 1390 1400
EEGDEDFDER SEAPRRPSRK GLRNDKDKPL PPLLARVGGN IEVLGFNARQ
1410 1420 1430 1440 1450
RKAFLNAIMR YGMPPQDAFT TQWLVRDLRG KSEKEFKAYV SLFMRHLCEP
1460 1470 1480 1490 1500
GADGAETFAD GVPREGLSRQ HVLTRIGVMS LIRKKVQEFE HVNGRWSMPE
1510 1520 1530 1540 1550
LAEVEENKKM SQPGSPSPKT PTPSTPGDTQ PNTPAPVPPA EDGIKIEENS
1560 1570 1580 1590 1600
LKEEESIEGE KEVKSTAPET AIECTQAPAP ASEDEKVVVE PPEGEEKVEK
1610 1620 1630 1640 1650
AEVKERTEEP METEPKGAAD VEKVEEKSAI DLTPIVVEDK EEKKEEEEKK
1660 1670 1680 1690 1700
EVMLQNGETP KDLNDEKQKK NIKQRFMFNI ADGGFTELHS LWQNEERAAT
1710 1720 1730 1740 1750
VTKKTYEIWH RRHDYWLLAG IINHGYARWQ DIQNDPRYAI LNEPFKGEMN
1760 1770 1780 1790 1800
RGNFLEIKNK FLARRFKLLE QALVIEEQLR RAAYLNMSED PSHPSMALNT
1810 1820 1830 1840 1850
RFAEVECLAE SHQHLSKESM AGNKPANAVL HKVLKQLEEL LSDMKADVTR
1860 1870 1880 1890
LPATIARIPP VAVRLQMSER NILSRLANRA PEPTPQQVAQ QQ
Length:1,892
Mass (Da):215,234
Last modified:February 28, 2018 - v2
Checksum:iCFFEEB8223C13BFC
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7B9Z5K7B9Z5_PANTR
CHD4 isoform 3
CHD4 CK820_G0048153
1,912Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04028163 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSPTRT00000042594; ENSPTRP00000039322; ENSPTRG00000004580

Similar proteinsi

Entry informationi

Entry nameiH2QZP6_PANTR
AccessioniPrimary (citable) accession number: H2QZP6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: September 12, 2018
This is version 47 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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