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Protein

Sulfhydryl oxidase

Gene

QSOX2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Sulfhydryl oxidaseUniRule annotation (EC:1.8.3.2UniRule annotation)
Gene namesi
Name:QSOX2Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 9

Organism-specific databases

VGNCiVGNC:4842 QSOX2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei665 – 682HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiH2QY61

Expressioni

Gene expression databases

BgeeiENSPTRG00000021547

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000036896

Structurei

3D structure databases

ProteinModelPortaliH2QY61
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 178ThioredoxinInterPro annotationAdd BLAST145
Domaini421 – 530ERV/ALR sulfhydryl oxidaseInterPro annotationAdd BLAST110

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1731 Eukaryota
ENOG410XVJT LUCA
GeneTreeiENSGT00390000008045
InParanoidiH2QY61
KOiK10758
OMAiLQTMRRY
OrthoDBiEOG091G038J
TreeFamiTF316749

Family and domain databases

Gene3Di1.20.120.310, 1 hit
InterProiView protein in InterPro
IPR036774 ERV/ALR_sulphydryl_oxid_sf
IPR017905 ERV/ALR_sulphydryl_oxidase
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain
PfamiView protein in Pfam
PF04777 Evr1_Alr, 1 hit
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
SSF69000 SSF69000, 1 hit
PROSITEiView protein in PROSITE
PS51324 ERV_ALR, 1 hit
PS51352 THIOREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

H2QY61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAGAAVAR SPGIGAGPAL RARRSPPPRA ARLPRLLVLL AAAAVGPGAG
60 70 80 90 100
GAARLYRAGE DAVWVLDSGS VRGATANSSA AWLVQFYSSW CGHCIGYAPT
110 120 130 140 150
WRALAGDVRD WASAIRVAAL DCMEEKNQAV CHDYDIHFYP TFRYFKAFTK
160 170 180 190 200
EFTTGENFKG PDRELRTVRQ TMIDFLQNHT EGSRPPACPR LDPIQPSDVL
210 220 230 240 250
SLLDNRGSHY VAIVFESNSS YLGREVILDL IPYESIVVTR ALDGDKAFLE
260 270 280 290 300
KLGVSSVPSC YLIYPNGSHG LINVVKPLRA FFSSYLKSLP DVRKKSLPLP
310 320 330 340 350
EKPHKEENSE IVVWREFDKS KLYTADLESG LHYLLRVELA AHKSLAGAEL
360 370 380 390 400
KTLKDFVTVL AKLFPGRPPV KKLLEMLQEW LASLPLDRIP YNAVLDLVNN
410 420 430 440 450
KMRISGIFLT NHIKWVGCQG SRSELRGYPC SLWKLFHTLT VEASTHPDAL
460 470 480 490 500
VGTGFEDDPQ AVLQTMRRYI HTFFGCKECG EHFEEMAKES MDSVKTPDQA
510 520 530 540 550
ILWLWKKHNM VNGRLAGHLS EDPRFPKLQW PTPDLCPACH EEIKGLASWD
560 570 580 590 600
EGHVLTLLKQ HYGRDNLLDT YSADQGDSSE GGTLARGEEE EKRLTPPEVS
610 620 630 640 650
HGDRDTQSVR PPGALGPRPA LPESLHHSLD GKLQSLDGPG AHKEVGGAAP
660 670 680 690
FLGVDFSSLD MSLCVVLYVA SSLFLMVMYF FFRVRSRRWK VKHHHPAV
Length:698
Mass (Da):77,481
Last modified:February 28, 2018 - v2
Checksum:iFB2B22D09DA19F8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04057940 Genomic DNA No translation available.
GABC01010229 mRNA Translation: JAA01109.1
RefSeqiXP_016817577.1, XM_016962088.1

Genome annotation databases

EnsembliENSPTRT00000039927; ENSPTRP00000036896; ENSPTRG00000021547
GeneIDi464853
KEGGiptr:464853

Similar proteinsi

Entry informationi

Entry nameiH2QY61_PANTR
AccessioniPrimary (citable) accession number: H2QY61
Secondary accession number(s): K7AHU3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 39 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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