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Protein

Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Gene

C1GALT1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.UniRule annotation

Catalytic activityi

UDP-alpha-D-galactose + N-acetyl-alpha-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationImported, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1UniRule annotation (EC:2.4.1.122UniRule annotation)
Gene namesi
Name:C1GALT1Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 7

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSPTRG00000018925

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000032336

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG2246 Eukaryota
ENOG410YRJG LUCA
GeneTreeiENSGT00530000063264
KOiK00731
OMAiYQPTLPE
OrthoDBiEOG091G0BLV
TreeFamiTF317293

Family and domain databases

InterProiView protein in InterPro
IPR026842 C1GALT1
IPR003378 Fringe-like
PANTHERiPTHR23033:SF13 PTHR23033:SF13, 1 hit
PfamiView protein in Pfam
PF02434 Fringe, 1 hit

Sequencei

Sequence statusi: Complete.

H2QU65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEIHFREMA SKSWLNFLTF LCGSAIGFLL CSQLFSILLG EKGDTQPNVL
60 70 80 90 100
HNDPHARHSD DNGQNHLEGQ MNFNADSSQH KDENTDIAEN LYHKVRILCW
110 120 130 140 150
VMTGPQNLEK KAKHVKATWA QRCNKVLFMS SEENKDFPAV GLKTKEGRDQ
160 170 180 190 200
LYWKTIKAFQ YVHEHYLEDA DWFLKADDDT YVILDNLRWL LSKYDPEEPI
210 220 230 240 250
YFGRRFKPYV KQGYMSGGAG YVLSKEALKR FVDAFKTDKC THSSSIEDLA
260 270 280 290 300
LGRCMEIMNV EAGDSRDTIG KETFHPFVPE HHLIKGYLPR TFWYWNYNYY
310 320 330 340 350
PPVEGPGCCS DLAVSFHYVD STTMYELEYL VYHLRPYGYL YRYQPTLPEH
360 370
ILKEISQANK NEDTKVKLGN P
Length:371
Mass (Da):43,181
Last modified:February 28, 2018 - v2
Checksum:i6CD642C1A5ACC40D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC189686 Genomic DNA No translation available.
AC193185 Genomic DNA No translation available.
GABC01002636 mRNA Translation: JAA08702.1
GABF01006935 mRNA Translation: JAA15210.1
GABD01001993 mRNA Translation: JAA31107.1
GABD01001992 mRNA Translation: JAA31108.1
GABD01001991 mRNA Translation: JAA31109.1
GABE01006634 mRNA Translation: JAA38105.1
RefSeqiXP_001143970.1, XM_001143970.5
XP_009450909.1, XM_009452634.2
XP_009450910.1, XM_009452635.2

Genome annotation databases

EnsembliENSPTRT00000034990; ENSPTRP00000032336; ENSPTRG00000048932
GeneIDi472288
KEGGiptr:472288

Similar proteinsi

Entry informationi

Entry nameiH2QU65_PANTR
AccessioniPrimary (citable) accession number: H2QU65
Secondary accession number(s): K7DCS8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: April 25, 2018
This is version 39 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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