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Protein
Submitted name:

DNA polymerase eta

Gene

POLH

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase etaImported
Submitted name:
POLH isoform 1Imported
Submitted name:
Polymerase (DNA directed), etaImported
Gene namesi
Name:POLHImported
ORF Names:CK820_G0007276Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 6

Organism-specific databases

VGNCiVGNC:13033 POLH

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSPTRG00000018205 Expressed in 6 organ(s), highest expression level in testis

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000031111

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 259UmuCInterPro annotationAdd BLAST251

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili345 – 365Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2095 Eukaryota
COG0389 LUCA
GeneTreeiENSGT00530000062942
OMAiYAMCRGI
OrthoDBiEOG091G04Z9
TreeFamiTF103010

Family and domain databases

Gene3Di3.30.1490.100, 1 hit
InterProiView protein in InterPro
IPR017061 DNA_pol_eta/kappa/iota/IV
IPR036775 DNA_pol_Y-fam_lit_finger_sf
IPR017961 DNA_pol_Y-fam_little_finger
IPR001126 UmuC
PfamiView protein in Pfam
PF00817 IMS, 1 hit
PF11799 IMS_C, 1 hit
PIRSFiPIRSF036603 DPol_eta, 1 hit
SUPFAMiSSF100879 SSF100879, 1 hit
PROSITEiView protein in PROSITE
PS50173 UMUC, 1 hit

Sequencei

Sequence statusi: Complete.

H2QT29-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATGQDRVVA LVDMDCFFVQ VEQRQNPHLR NKPCAVVQYK SWKGGGIIAV
60 70 80 90 100
SYEARAFGVT RSMWADDAKK LCPDLLLAQV RESRGKANLT KYREASVEVM
110 120 130 140 150
EIMSRFAVIE RASIDEAYVD LTSAVQERLQ KLQGQPISAD LLPSTYIEGL
160 170 180 190 200
PQGPTTAEET VQKEGMRKQG LFQWLDSLQI DNLTSPDLQL TVGAVIVEEM
210 220 230 240 250
RAAIERETGF QCSAGISHNK VLAKLACGLN KPNRQTLVSH GSVPQLFSQM
260 270 280 290 300
PIRKIRSLGG KLGASVIEIL GIEYMGELTQ FTESQLQSHF GEKNGSWLYA
310 320 330 340 350
MCRGIEHDPV KPRQLPKTIG CSKNFPGKTA LATREQVQWW LLQLAQELEE
360 370 380 390 400
RLTKDRNDND RVATQLVVSI RVQGDKRLSS LRRCCALTRY DAHKMSHDAF
410 420 430 440 450
TVIKNCNTSG IQTEWSPPLT MLFLCATKFS ASAPSSSTDI TSFLSSDPSS
460 470 480 490 500
LPKVPVTSSE AKTQGSGPAV TATKKATTSL ESFFQKAAER QKVKEASLSS
510 520 530 540 550
LTAPTQAPMS NSPSKPSLPF QTSQSTGTEP FFKQKSLLLK QKQLNNSSVS
560 570 580 590 600
SPQQNPWSNC KALPNSLPTE YPGCVPVCEG VSKLEESSKA TPAEMDLAHN
610 620 630 640 650
SQSMHASSAS KSALEVTQKA TPTPSLLAAE DQVPCEKCGS LVPVWDMPEH
660 670 680 690 700
MDYHFALELQ KSFLQPHSSN PQVVSAVSHQ GKRNPKSPLA CTNKRPRPEG
710
MQTLESFFKP LTH
Length:713
Mass (Da):78,372
Last modified:March 21, 2012 - v1
Checksum:i1CD59F21F0317A72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04022883 Genomic DNA No translation available.
GABC01008341 mRNA Translation: JAA02997.1
GABF01003009 mRNA Translation: JAA19136.1
GABD01003355 mRNA Translation: JAA29745.1
GABE01010341 mRNA Translation: JAA34398.1
GABE01010340 mRNA Translation: JAA34399.1
GABE01010339 mRNA Translation: JAA34400.1
GABE01010338 mRNA Translation: JAA34401.1
NBAG03000221 Genomic DNA Translation: PNI77460.1
RefSeqiXP_518497.1, XM_518497.6

Genome annotation databases

EnsembliENSPTRT00000033666; ENSPTRP00000031111; ENSPTRG00000018205
GeneIDi462720

Similar proteinsi

Entry informationi

Entry nameiH2QT29_PANTR
AccessioniPrimary (citable) accession number: H2QT29
Secondary accession number(s): A0A2J8P0D0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: September 12, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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