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Protein

Cation-transporting ATPase

Gene

ATP13A4

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cation-transporting ATPaseUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:ATP13A4Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 3

Organism-specific databases

VGNCiVGNC:1742 ATP13A4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei268 – 287HelicalUniRule annotationAdd BLAST20
Transmembranei444 – 465HelicalUniRule annotationAdd BLAST22
Transmembranei477 – 500HelicalUniRule annotationAdd BLAST24
Transmembranei947 – 966HelicalUniRule annotationAdd BLAST20
Transmembranei972 – 993HelicalUniRule annotationAdd BLAST22
Transmembranei1014 – 1036HelicalUniRule annotationAdd BLAST23
Transmembranei1082 – 1100HelicalUniRule annotationAdd BLAST19
Transmembranei1112 – 1132HelicalUniRule annotationAdd BLAST21
Transmembranei1152 – 1173HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiH2QNZ7

Expressioni

Gene expression databases

BgeeiENSPTRG00000015750 Expressed in 4 organ(s), highest expression level in prefrontal cortex

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000027089

Structurei

3D structure databases

ProteinModelPortaliH2QNZ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 265Cation_ATPase_NInterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0208 Eukaryota
ENOG410XRCA LUCA
GeneTreeiENSGT00530000063001
InParanoidiH2QNZ7
OMAiWKLLIKE
OrthoDBiEOG091G01IL
TreeFamiTF300331

Family and domain databases

Gene3Di3.40.1110.10, 2 hits
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006544 P-type_TPase_V
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00690 Cation_ATPase_N, 1 hit
PF12409 P5-ATPase, 1 hit
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 3 hits
TIGR01657 P-ATPase-V, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H2QNZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGETFPEIR KSQLRSCGGS ESWSSSWKRL PGKVREEVWN NLFMGHFEKG
60 70 80 90 100
QHALLNEGEE NEMEIFGYRT QGCRKSLCLA GSIFSFGILP LVFYWRPAWH
110 120 130 140 150
VWAHCVPCSL QEADTVLLRT TDEFQIYSWK KVIWIYLSAL NSAFGLTPDH
160 170 180 190 200
PLMTDEEYII NRAIRKPDLK VRCIKVQKIR YVWNYLEGQF QKIGSLEDWL
210 220 230 240 250
SSAKIHQKFG SGLTREEQEI RRLICGPNTI DVEVTPIWKL LIKEVLNPFY
260 270 280 290 300
IFQLFSVCLW FSEDYKEYAF AIIIMSIISI SLTVYDLREQ SVKLHHLVES
310 320 330 340 350
HNSITVSVCG RKAGVQELES RVLVPGDLLI LTGNKVLMPC DAVLIEGSCV
360 370 380 390 400
VDEGMLTGES IPVTKTPLPK MDSSVPWKTQ SEADYKRHVL FCGTEVIQAK
410 420 430 440 450
AACSGTVRAV VLQTGFNTAK GDLVRSILYP KPVNFQLYRD AIRFLLCLVG
460 470 480 490 500
TATIGMIYTL CVYVLSGEPP EEVVRKALDV ITIAVPPALP AALTTGIIYA
510 520 530 540 550
QRRLKKRGIF CISPQRINVC GQLNLVCFDK TGTLTRDGLD LWGVVSCDRN
560 570 580 590 600
GFQEVHSFAS GQALPWGPLC AAMASCHSLI LLDGTIQGDP LDLKMFEATT
610 620 630 640 650
WEMAFSGDDF HIKGVPAHAM VVKPCRTASQ VPVEGIAILH QFPFSSALQR
660 670 680 690 700
MTVIVQEMGG DRLAFMKGAP ERVASFCQPE TVPTSFVSEL QIYTTQGFRV
710 720 730 740 750
IALAYKKLEN DHHATTLTRE TVESDLIFLG LLILENRLKE ETKPVLEELI
760 770 780 790 800
SARIRTVMIT GDNLQTAITV ARKSGMVSES QKVILIEANE TTGSSSASIS
810 820 830 840 850
WTLVEEKKHI TYGNQDNYIN IRDEVSDKGR EGSYHFALTG KSFHVISQHF
860 870 880 890 900
SSLLPKILIN GTIFARMSPG QKSSLVEEFQ KLDYFVGMCG DGANDCGALK
910 920 930 940 950
MAHVGISLSE QEASVASPFT SKTPNIECVP HLIKEGRAAL VTSFCMFKYM
960 970 980 990 1000
ALYSMIQYVG VLLLYWETNS LSNYQFLFQD LAITTLIGVT MNLNGAYPKL
1010 1020 1030 1040 1050
VPFRPAGRLI SPPLLLSVIF NILLSLAMHI AGFILVQRQP WYSVEIHSAC
1060 1070 1080 1090 1100
TVQNESISEL TMSPTAPEKM ESNSTFTSFE NTTIWFLGTI NCITVALVFS
1110 1120 1130 1140 1150
KGKPFRQPTY TNYIFVFVLI IQLGVCLFIL FADIPELYRR LDLLCTPVLW
1160 1170 1180 1190 1200
RASIVIMLSL NFIVSLVAEE AVIENRALWM MIKRRFGYQS KSQYRIWQRD
1210 1220 1230
LANDPSWPPL NQTSHSDMPE CGRGVSYSNP VFESNEEQL
Length:1,239
Mass (Da):138,997
Last modified:February 28, 2018 - v2
Checksum:iF4F21D22C2D7E5B7
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3T921A0A2I3T921_PANTR
Cation-transporting ATPase
ATP13A4
1,196Annotation score:
A0A2I3TMV6A0A2I3TMV6_PANTR
Cation-transporting ATPase
ATP13A4
1,210Annotation score:
A0A2I3SMF8A0A2I3SMF8_PANTR
Cation-transporting ATPase
ATP13A4
1,188Annotation score:
A0A2I3RCU9A0A2I3RCU9_PANTR
ATPase 13A4
ATP13A4
87Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04067360 Genomic DNA No translation available.
RefSeqiXP_016797999.1, XM_016942510.1

Genome annotation databases

EnsembliENSPTRT00000029347; ENSPTRP00000027089; ENSPTRG00000015750
GeneIDi460940

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04067360 Genomic DNA No translation available.
RefSeqiXP_016797999.1, XM_016942510.1

3D structure databases

ProteinModelPortaliH2QNZ7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000027089

Proteomic databases

PaxDbiH2QNZ7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000029347; ENSPTRP00000027089; ENSPTRG00000015750
GeneIDi460940

Organism-specific databases

CTDi84239
VGNCiVGNC:1742 ATP13A4

Phylogenomic databases

eggNOGiKOG0208 Eukaryota
ENOG410XRCA LUCA
GeneTreeiENSGT00530000063001
InParanoidiH2QNZ7
OMAiWKLLIKE
OrthoDBiEOG091G01IL
TreeFamiTF300331

Gene expression databases

BgeeiENSPTRG00000015750 Expressed in 4 organ(s), highest expression level in prefrontal cortex

Family and domain databases

Gene3Di3.40.1110.10, 2 hits
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006544 P-type_TPase_V
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00690 Cation_ATPase_N, 1 hit
PF12409 P5-ATPase, 1 hit
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 3 hits
TIGR01657 P-ATPase-V, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH2QNZ7_PANTR
AccessioniPrimary (citable) accession number: H2QNZ7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: September 12, 2018
This is version 47 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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