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Protein
Submitted name:

NAD(P)H quinone dehydrogenase 1

Gene

NQO1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
NAD(P)H quinone dehydrogenase 1Imported
Submitted name:
NQO1 isoform 1Imported
Gene namesi
Name:NQO1Imported
ORF Names:CK820_G0044569Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 16

Organism-specific databases

VGNCiVGNC:9094 NQO1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiH2QBF4

Expressioni

Gene expression databases

BgeeiENSPTRG00000008284 Expressed in 5 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014148

Structurei

3D structure databases

SMRiH2QBF4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 211Flavodoxin_2InterPro annotationAdd BLAST207

Phylogenomic databases

eggNOGiENOG410IKWF Eukaryota
COG2249 LUCA
GeneTreeiENSGT00440000033410
InParanoidiH2QBF4
KOiK00355
OMAiLFPIHHG
OrthoDBiEOG091G183R
TreeFamiTF300296

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR003680 Flavodoxin_fold
IPR029039 Flavoprotein-like_sf
PfamiView protein in Pfam
PF02525 Flavodoxin_2, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

H2QBF4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI
60 70 80 90 100
ISRKDITGKL KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF
110 120 130 140 150
QFPLQWFGVP AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG
160 170 180 190 200
GSGSMYSLQG IHGDMNVILW PIQSGILHFC GFQVLEPQLT YSIGHTPADA
210 220 230 240 250
RIQILEGWKK RLENIWDETP LYFAPSSLFD LNFQAGFLMK KEVQDEEKNK
260 270
KFGLSVGHHL GKSIPTDNQI KARK
Length:274
Mass (Da):30,868
Last modified:February 28, 2018 - v2
Checksum:iA4010462AD00F3FE
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3T0V6A0A2I3T0V6_PANTR
NAD(P)H quinone dehydrogenase 1
NQO1 CK820_G0044569
240Annotation score:
A0A2I3RJV8A0A2I3RJV8_PANTR
NAD(P)H quinone dehydrogenase 1
NQO1 CK820_G0044569
236Annotation score:
A0A2I3RSA8A0A2I3RSA8_PANTR
NAD(P)H quinone dehydrogenase 1
NQO1 CK820_G0044569
202Annotation score:
A0A2I3RHE4A0A2I3RHE4_PANTR
NAD(P)H quinone dehydrogenase 1
NQO1 CK820_G0044569
269Annotation score:
A0A2I3TIB8A0A2I3TIB8_PANTR
NAD(P)H quinone dehydrogenase 1
NQO1
273Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04051802 Genomic DNA No translation available.
NBAG03000083 Genomic DNA Translation: PNI90933.1
RefSeqiXP_016785579.1, XM_016930090.1

Genome annotation databases

EnsembliENSPTRT00000015279; ENSPTRP00000014148; ENSPTRG00000008284
GeneIDi468012
KEGGiptr:468012

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04051802 Genomic DNA No translation available.
NBAG03000083 Genomic DNA Translation: PNI90933.1
RefSeqiXP_016785579.1, XM_016930090.1

3D structure databases

SMRiH2QBF4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000014148

Proteomic databases

PaxDbiH2QBF4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000015279; ENSPTRP00000014148; ENSPTRG00000008284
GeneIDi468012
KEGGiptr:468012

Organism-specific databases

CTDi1728
VGNCiVGNC:9094 NQO1

Phylogenomic databases

eggNOGiENOG410IKWF Eukaryota
COG2249 LUCA
GeneTreeiENSGT00440000033410
InParanoidiH2QBF4
KOiK00355
OMAiLFPIHHG
OrthoDBiEOG091G183R
TreeFamiTF300296

Gene expression databases

BgeeiENSPTRG00000008284 Expressed in 5 organ(s), highest expression level in liver

Family and domain databases

Gene3Di3.40.50.360, 1 hit
InterProiView protein in InterPro
IPR003680 Flavodoxin_fold
IPR029039 Flavoprotein-like_sf
PfamiView protein in Pfam
PF02525 Flavodoxin_2, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH2QBF4_PANTR
AccessioniPrimary (citable) accession number: H2QBF4
Secondary accession number(s): A0A2J8Q3U1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: February 28, 2018
Last modified: September 12, 2018
This is version 37 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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