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Protein
Submitted name:

CTSG isoform 2

Gene

CTSG

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPSiS01.133

Names & Taxonomyi

Protein namesi
Submitted name:
CTSG isoform 2Imported
Submitted name:
Cathepsin GImported
Gene namesi
Name:CTSGImported
ORF Names:CK820_G0029735Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 14

Organism-specific databases

VGNCiVGNC:3447 CTSG

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501509252919 – 255Sequence analysisAdd BLAST237

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiH2Q839

Expressioni

Gene expression databases

BgeeiENSPTRG00000006224 Expressed in 5 organ(s), highest expression level in liver

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000010565

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 243Peptidase S1InterPro annotationAdd BLAST223

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118895
InParanoidiH2Q839
KOiK01319
OMAiYPYMAYL
OrthoDBiEOG091G0G5F
TreeFamiTF333630

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

H2Q839-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQPLLLLLAF LLPTGAEAGE IIGGQESRPH SRPYMAYLQI QSPAGQSRCG
60 70 80 90 100
GFLVREDFVL TAAHCWGSNI NVTLGAHNVQ RRENTQQHIT ARRAIRHPQY
110 120 130 140 150
NQRTIQNDIM LLQLSRRVRR NRNVNPVALP RAQEGLRPGT RCTVAGWGRV
160 170 180 190 200
SLRRGTDTLR EVQLRVQRDS QCLRIFDSYD PRRQICVGDR RERKSAFKGD
210 220 230 240 250
SGGPLLCNNV AHGIVSYGKS SGVPPEVFTR VSSFLPWIRR TMRSFKLLDQ

METPL
Length:255
Mass (Da):28,880
Last modified:March 21, 2012 - v1
Checksum:i8E9AF2DBDCFCD8E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04059404 Genomic DNA No translation available.
NBAG03000032 Genomic DNA Translation: PNI96893.1
RefSeqiXP_522810.1, XM_522810.5

Genome annotation databases

EnsembliENSPTRT00000011419; ENSPTRP00000010565; ENSPTRG00000006224
GeneIDi467413
KEGGiptr:467413

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04059404 Genomic DNA No translation available.
NBAG03000032 Genomic DNA Translation: PNI96893.1
RefSeqiXP_522810.1, XM_522810.5

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000010565

Protein family/group databases

MEROPSiS01.133

Proteomic databases

PaxDbiH2Q839

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000011419; ENSPTRP00000010565; ENSPTRG00000006224
GeneIDi467413
KEGGiptr:467413

Organism-specific databases

CTDi1511
VGNCiVGNC:3447 CTSG

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118895
InParanoidiH2Q839
KOiK01319
OMAiYPYMAYL
OrthoDBiEOG091G0G5F
TreeFamiTF333630

Gene expression databases

BgeeiENSPTRG00000006224 Expressed in 5 organ(s), highest expression level in liver

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH2Q839_PANTR
AccessioniPrimary (citable) accession number: H2Q839
Secondary accession number(s): A0A2J8QKU1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: November 7, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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