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Protein
Submitted name:

KCNQ4 isoform 1

Gene

KCNQ4

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
KCNQ4 isoform 1Imported
Submitted name:
Potassium voltage-gated channel subfamily Q member 4Imported
Gene namesi
Name:KCNQ4Imported
ORF Names:CK820_G0025479Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:8060 KCNQ4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei99 – 121HelicalSequence analysisAdd BLAST23
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Transmembranei174 – 199HelicalSequence analysisAdd BLAST26
Transmembranei239 – 258HelicalSequence analysisAdd BLAST20
Transmembranei299 – 324HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiH2PYS7

Expressioni

Gene expression databases

BgeeiENSPTRG00000000597

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000001033

Structurei

3D structure databases

ProteinModelPortaliH2PYS7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 324Ion_transInterPro annotationAdd BLAST225
Domaini464 – 646KCNQ_channelInterPro annotationAdd BLAST183

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1419 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00550000074513
InParanoidiH2PYS7
OMAiWAFVYHV
OrthoDBiEOG091G02ZT
TreeFamiTF315186

Family and domain databases

InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR003937 K_chnl_volt-dep_KCNQ
IPR013821 K_chnl_volt-dep_KCNQ_C
IPR015573 KCQN4
IPR028325 VG_K_chnl
PANTHERiPTHR11537 PTHR11537, 1 hit
PTHR11537:SF4 PTHR11537:SF4, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
PF03520 KCNQ_channel, 1 hit
PRINTSiPR00169 KCHANNEL
PR01459 KCNQCHANNEL

Sequencei

Sequence statusi: Complete.

H2PYS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEAPPRRLG LGPPPGDAPR AELVALTAVQ SEQGEAGGGG SPRRLGLLGS
60 70 80 90 100
PLPPGAPLPG PGSGSGSACG QRSSAAHKRY RRLQNWVYNV LERPRGWAFV
110 120 130 140 150
YHVFIFLLVF SCLVLSVLST IQEHQELANE CLLILEFVMI VVFGLEYIVR
160 170 180 190 200
VWSAGCCCRY RGWQGRFRFA RKPFCVIDFI VFVASVAVIA AGTQGNIFAT
210 220 230 240 250
SALRSMRFLQ ILRMVRMDRR GGTWKLLGSV VYAHSKELIT AWYIGFLVLI
260 270 280 290 300
FASFLVYLAE KDANSDFSSY ADSLWWGTIT LTTIGYGDKT PHTWLGRVLA
310 320 330 340 350
AGFALLGISF FALPAGILGS GFALKVQEQH RQKHFEKRRM PAANLIQAAW
360 370 380 390 400
RLYSTDMSRA YLTATWYYYD SILPSFRELA LLFEHVQRAR NGGLRPLEVR
410 420 430 440 450
RAPVPDGAPS RYPPVATCHR PGSTSFCPGE SSRMGIKDRI RMGSSQRRTG
460 470 480 490 500
PSKQHLAPPT MPTSPSSEQV GEATSPTKVQ KSWSFNDRTR FRASLRLKPR
510 520 530 540 550
TSAEDAPSEE VAEEKSYQCE LTVDDIMPAV KTVIRSVRIL KFLVAKRKFK
560 570 580 590 600
ETLRPYDVKD VIEQYSAGHL DMLGRIKSLQ TRVDQIVGRG PGDRKAREKG
610 620 630 640 650
DKGPSDAEVV DEISMMGRVV KVEKQVQSIE HKLDLLLGFY SRCLRSGTSA
660 670 680 690
SLGAVQVPLF DPDITSDYHS PVDHEDISVS AQTLSISRSV STNMD
Length:695
Mass (Da):77,087
Last modified:March 21, 2012 - v1
Checksum:iEB8234CE1350F78E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04033013 Genomic DNA No translation available.
NBAG03000275 Genomic DNA Translation: PNI52525.1
RefSeqiXP_513360.2, XM_513360.4

Genome annotation databases

EnsembliENSPTRT00000001143; ENSPTRP00000001033; ENSPTRG00000000597
GeneIDi456800

Similar proteinsi

Entry informationi

Entry nameiH2PYS7_PANTR
AccessioniPrimary (citable) accession number: H2PYS7
Secondary accession number(s): A0A2J8LZ10
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 23, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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