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Protein
Submitted name:

3-hydroxymethyl-3-methylglutaryl-CoA lyase

Gene

HMGCL

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
3-hydroxymethyl-3-methylglutaryl-CoA lyaseImported
Submitted name:
HMGCL isoform 2Imported
Gene namesi
Name:HMGCLImported
ORF Names:CK820_G0041608Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:1261 HMGCL

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSPTRG00000000339

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000000589

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 300Pyruvate carboxyltransferaseInterPro annotationAdd BLAST268

Phylogenomic databases

eggNOGiKOG2368 Eukaryota
COG0119 LUCA
GeneTreeiENSGT00390000017690
KOiK01640
OMAiFGGCPMA
OrthoDBiEOG091G0DA9
TreeFamiTF105363

Family and domain databases

Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR000138 HMG_CoA_lyase_AS
IPR000891 PYR_CT
PfamiView protein in Pfam
PF00682 HMGL-like, 1 hit
PROSITEiView protein in PROSITE
PS01062 HMG_COA_LYASE, 1 hit
PS50991 PYR_CT, 1 hit

Sequencei

Sequence statusi: Complete.

H2PYB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAMRKALPR RLVGLASLRA VSTSSMGTLP KRVKIVEVGP RDGLQNEKNI
60 70 80 90 100
VSTPVKIKLV DMLSEAGLSV IETTSFVSPK WVPQMGDHTE VLKGIQKFPG
110 120 130 140 150
INYPVLTPNL KGFEAAVAAG AKEVVIFGAA SELFTKKNIN CSIEESFQRF
160 170 180 190 200
DAILKAAQSA NISVRGYVSC ALGCPYEGKI SPAKVAEVTK KFYSMGCYEI
210 220 230 240 250
SLGDTIGVGT PGIMKDMLSA VMQEVPLAAL AVHCHDTYGQ ALANTLMALQ
260 270 280 290 300
MGVSVVDSSV AGLGGCPYAQ GASGNLATED LVYMLEGLGI HTGVNLQKLL
310 320
EAGNFICQAL NRKTSSKVAQ ATCKL
Length:325
Mass (Da):34,346
Last modified:March 21, 2012 - v1
Checksum:iB82D7667A103A650
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC192160 Genomic DNA No translation available.
GABF01007958 mRNA Translation: JAA14187.1
GABD01009657 mRNA Translation: JAA23443.1
NBAG03000395 Genomic DNA Translation: PNI29722.1
RefSeqiXP_001166273.1, XM_001166273.4

Genome annotation databases

EnsembliENSPTRT00000000664; ENSPTRP00000000589; ENSPTRG00000000339
GeneIDi456624
KEGGiptr:456624

Similar proteinsi

Entry informationi

Entry nameiH2PYB3_PANTR
AccessioniPrimary (citable) accession number: H2PYB3
Secondary accession number(s): A0A2J8K423
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: May 23, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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