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Protein
Submitted name:

TBC1 domain family member 8B

Gene

TBC1D8B

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
TBC1 domain family member 8BImported
Gene namesi
Name:TBC1D8BImported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome X

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000023063

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini545 – 732Rab-GAP TBCInterPro annotationAdd BLAST188
Domaini916 – 951EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG4347 Eukaryota
COG5210 LUCA
GeneTreeiENSGT00760000119137
InParanoidiH2PWE5
OMAiEITKHWD
OrthoDBiEOG091G00RI
TreeFamiTF313145

Family and domain databases

CDDicd13350 PH-GRAM1_TBC1D8B, 1 hit
cd13352 PH-GRAM2_TBC1D8B, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR004182 GRAM
IPR011993 PH-like_dom_sf
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR036012 TBC1D8B_PH-GRAM1
IPR036015 TBC1D8B_PH-GRAM2
PfamiView protein in Pfam
PF02893 GRAM, 2 hits
PF00566 RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00568 GRAM, 2 hits
SM00164 TBC, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF47923 SSF47923, 2 hits
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
PS50086 TBC_RABGAP, 1 hit

Sequencei

Sequence statusi: Complete.

H2PWE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SLPTWERREG WGKCGKPEPE LLSPEEDLVG GEAEGKRRVE SEVRRASRSL
60 70 80 90 100
FPVGTKFAMW LKPEEVLLKN ALKLWLMERS NDYFVLQRRR GYGEEGGGGL
110 120 130 140 150
TGLLVGTLDS VLDSTAKVAP FRILHQTPDS QVYLSIACGA NREEITKHWD
160 170 180 190 200
WLEQNIMKTL SVFDSNEDIT NFVQGKIRGL IAEEGKHCFA KEDDPEKFRE
210 220 230 240 250
ALLKFEKCFG LPEKEKLVTY YSCSYWKGRV PCQGWLYLST NFLSFYSFLL
260 270 280 290 300
GSEIKLIISW DEVSKLEKTS NVILTESVHV CSQGENHYFS MFLHINQTYL
310 320 330 340 350
LMEQLANYAI RRLFDKETFD NDPVLYNPLQ ITKRGLENRA HSEQFNAFFR
360 370 380 390 400
LPKGESLKEV HECSLWVPFS HFNTHGKMCI SENYICFASQ DGNQCSVIIP
410 420 430 440 450
LREVLAIDKT NDSSKSVIIS IKGKTAFRFH EVKDFEQLVA KLRLRCGAAS
460 470 480 490 500
TQYHDISTEL AISSESTETS DNFEVQSLTS QRECSKTVNT EALMMVFHPQ
510 520 530 540 550
NLETLNSKML KEKMKEQSWK ILFAECGRGV SMFRTKKTRD LVVRGIPETL
560 570 580 590 600
RGELWMLFSG AVNDMATNPG YYTEVVEQSL GTCNLATEEI ERDLRRSLPE
610 620 630 640 650
HPAFQSDTGI SALRRVLTAY AYRNPKIGYC QAMNILTSVL LLYAKEEEAF
660 670 680 690 700
WLLVAVCERM LPDYFNRRII GALVDQAVFE ELIRDHLPQL TEHMTDMTFF
710 720 730 740 750
SSVSLSWFLT LFISVLPIES AVNVVDCFFY DGIKAILQLG LAILDYNLDK
760 770 780 790 800
LLTCKDDAEA VTALNRFFDN VTNKDSPLPS NVQQGSNVSD EKTSHTRVDI
810 820 830 840 850
TDLIRESNEK YGNIRYEDIH SMRCRNRLYV IQTLEETTKQ NVLRVVSQDV
860 870 880 890 900
KLSLHELDQL YVIFKKELFL SCYWCLGCPV LKHHDPSLPY LEQYQIDCQQ
910 920 930 940 950
FRALYHLLCP WAHSANRDSL ALWTFRLLDE NSDCLINFKE FSSAIDIMYN
960 970 980 990 1000
GSFTEKLKLL FKLHIPPAYT EVKSKDASKG DELSKEELLY FSQLRVSKPA
1010 1020 1030 1040 1050
NEKEAQSAKH SPEKGKGKID IQAYLSQWQD ELFKKEENIK DLPRMNQSQF
1060 1070 1080 1090 1100
IQFSKTLYNL FHEDPEEESL YQAIAVVTSL LLRMEEVGRK LHSPTSSAKG
1110 1120 1130 1140 1150
FSGTVCGSGG PSEEKTGSHL EKDPCSFREE PQWSFAFEQI LASLLNEPAL
1160 1170
VRFFEKPIDV KAKLENAKIS QLRSRTKM
Length:1,178
Mass (Da):135,133
Last modified:March 21, 2012 - v1
Checksum:iB2C10702C123BB0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01206444 Genomic DNA No translation available.
ABGA01206445 Genomic DNA No translation available.
ABGA01206446 Genomic DNA No translation available.
ABGA01206447 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSPPYT00000024033; ENSPPYP00000023063; ENSPPYG00000020605

Similar proteinsi

Entry informationi

Entry nameiH2PWE5_PONAB
AccessioniPrimary (citable) accession number: H2PWE5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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