UniProtKB - H2PRQ3 (H2PRQ3_PONAB)
Protein
Submitted name:
Uncharacterized protein
Gene
PAX5
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: Ensembl
GO - Biological processi
- adult behavior Source: Ensembl
- aging Source: Ensembl
- cerebral cortex development Source: Ensembl
- embryonic cranial skeleton morphogenesis Source: Ensembl
- lateral ventricle development Source: Ensembl
- negative regulation of histone H3-K9 methylation Source: Ensembl
- negative regulation of transcription by RNA polymerase II Source: Ensembl
- skeletal muscle cell differentiation Source: Ensembl
Keywordsi
Molecular function | Developmental proteinARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:PAX5Imported |
Organismi | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported |
Taxonomic identifieri | 9601 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Cytosol
- cytosol Source: Ensembl
Nucleus
- fibrillar center Source: Ensembl
- nucleoplasm Source: Ensembl
Keywords - Cellular componenti
NucleusARBA annotationFamily & Domainsi
Keywords - Domaini
Paired boxARBA annotationPhylogenomic databases
eggNOGi | KOG3862, Eukaryota |
GeneTreei | ENSGT00940000159636 |
HOGENOMi | CLU_019281_4_0_1 |
InParanoidi | H2PRQ3 |
OMAi | QPSCPIQ |
OrthoDBi | 592933at2759 |
TreeFami | TF315397 |
Family and domain databases
CDDi | cd00131, PAX, 1 hit |
Gene3Di | 1.10.10.10, 2 hits |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR043182, PAIRED_DNA_bd_dom IPR001523, Paired_dom IPR022130, Pax2_C IPR043565, PAX_fam IPR036388, WH-like_DNA-bd_sf |
PANTHERi | PTHR45636, PTHR45636, 1 hit |
Pfami | View protein in Pfam PF00292, PAX, 1 hit PF12403, Pax2_C, 1 hit |
PRINTSi | PR00027, PAIREDBOX |
SMARTi | View protein in SMART SM00351, PAX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00034, PAIRED_1, 1 hit PS51057, PAIRED_2, 1 hit |
i Sequence
Sequence statusi: Complete.
H2PRQ3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDLEKNYPTP RTSRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR
60 70 80 90 100
PCDISRQLRV SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA
110 120 130 140 150
EYKRQNPTMF AWEIRDRLLA ERVCDNDTVP SVSSINRIIR TKVQQPPNQP
160 170 180 190 200
VPASSHSIVS TGSVTQVSSV STDSAGSSYS ISGILGITSP SADTNKRKRD
210 220 230 240 250
EGIQESPVPN GHSLPGRDFL RKQMRGDLFT QQQLEVLDRV FERQHYSDIF
260 270 280 290 300
TTTEPIKPEQ TTEYSAMASL AGGLDDMKAN LASPTPADIG SSVPGPQSYP
310 320 330 340 350
IVTGRDLAST TLPGYPPHVP PAGQGSYSAP TLTGMVPGSE FSGTPYSHPQ
360 370 380 390
YSSYNDSWRF PNPGLLGSPY YYSAAARGAA PPAAATAYDR H
Sequence databases
RefSeqi | XP_002819659.1, XM_002819613.3 |
Genome annotation databases
Ensembli | ENSPPYT00000022226; ENSPPYP00000021364; ENSPPYG00000019064 |
GeneIDi | 100457719 |
KEGGi | pon:100457719 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_002819659.1, XM_002819613.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9601.ENSPPYP00000021364 |
Genome annotation databases
Ensembli | ENSPPYT00000022226; ENSPPYP00000021364; ENSPPYG00000019064 |
GeneIDi | 100457719 |
KEGGi | pon:100457719 |
Organism-specific databases
CTDi | 5079 |
Phylogenomic databases
eggNOGi | KOG3862, Eukaryota |
GeneTreei | ENSGT00940000159636 |
HOGENOMi | CLU_019281_4_0_1 |
InParanoidi | H2PRQ3 |
OMAi | QPSCPIQ |
OrthoDBi | 592933at2759 |
TreeFami | TF315397 |
Family and domain databases
CDDi | cd00131, PAX, 1 hit |
Gene3Di | 1.10.10.10, 2 hits |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR043182, PAIRED_DNA_bd_dom IPR001523, Paired_dom IPR022130, Pax2_C IPR043565, PAX_fam IPR036388, WH-like_DNA-bd_sf |
PANTHERi | PTHR45636, PTHR45636, 1 hit |
Pfami | View protein in Pfam PF00292, PAX, 1 hit PF12403, Pax2_C, 1 hit |
PRINTSi | PR00027, PAIREDBOX |
SMARTi | View protein in SMART SM00351, PAX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00034, PAIRED_1, 1 hit PS51057, PAIRED_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H2PRQ3_PONAB | |
Accessioni | H2PRQ3Primary (citable) accession number: H2PRQ3 Secondary accession number(s): A0A2J8T051 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 21, 2012 |
Last sequence update: | March 21, 2012 | |
Last modified: | December 2, 2020 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |