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UniProtKB - H2PPD9 (H2PPD9_PONAB)

Entry version 50 (07 Oct 2020)
Sequence version 1 (21 Mar 2012)
Previous versions | rss
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001595 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi325 ↔ 352PROSITE-ProRule annotation
Disulfide bondi701 ↔ 728PROSITE-ProRule annotation
Disulfide bondi1781 ↔ 1808PROSITE-ProRule annotation
Disulfide bondi1839 ↔ 1866PROSITE-ProRule annotation
Disulfide bondi1897 ↔ 1924PROSITE-ProRule annotation
Disulfide bondi1960 ↔ 1987PROSITE-ProRule annotation
Disulfide bondi2018 ↔ 2045PROSITE-ProRule annotation
Disulfide bondi2079 ↔ 2106PROSITE-ProRule annotation
Disulfide bondi2138 ↔ 2165PROSITE-ProRule annotation
Disulfide bondi2256 ↔ 2283PROSITE-ProRule annotation
Disulfide bondi2314 ↔ 2341PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9601.ENSPPYP00000020508

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 118CUBInterPro annotationAdd BLAST109
Domaini121 – 182SushiInterPro annotationAdd BLAST62
Domaini184 – 292CUBInterPro annotationAdd BLAST109
Domaini297 – 354SushiInterPro annotationAdd BLAST58
Domaini356 – 466CUBInterPro annotationAdd BLAST111
Domaini469 – 526SushiInterPro annotationAdd BLAST58
Domaini528 – 636CUBInterPro annotationAdd BLAST109
Domaini639 – 699SushiInterPro annotationAdd BLAST61
Domaini701 – 810CUBInterPro annotationAdd BLAST110
Domaini813 – 873SushiInterPro annotationAdd BLAST61
Domaini875 – 983CUBInterPro annotationAdd BLAST109
Domaini986 – 1047SushiInterPro annotationAdd BLAST62
Domaini1049 – 1157CUBInterPro annotationAdd BLAST109
Domaini1195 – 1254SushiInterPro annotationAdd BLAST60
Domaini1256 – 1364CUBInterPro annotationAdd BLAST109
Domaini1367 – 1426SushiInterPro annotationAdd BLAST60
Domaini1429 – 1464SushiInterPro annotationAdd BLAST36
Domaini1466 – 1562CUBInterPro annotationAdd BLAST97
Domaini1563 – 1625SushiInterPro annotationAdd BLAST63
Domaini1626 – 1687SushiInterPro annotationAdd BLAST62
Domaini1688 – 1752SushiInterPro annotationAdd BLAST65
Domaini1753 – 1810SushiInterPro annotationAdd BLAST58
Domaini1811 – 1868SushiInterPro annotationAdd BLAST58
Domaini1869 – 1926SushiInterPro annotationAdd BLAST58
Domaini1927 – 1989SushiInterPro annotationAdd BLAST63
Domaini1990 – 2047SushiInterPro annotationAdd BLAST58
Domaini2051 – 2108SushiInterPro annotationAdd BLAST58
Domaini2109 – 2167SushiInterPro annotationAdd BLAST59
Domaini2168 – 2227SushiInterPro annotationAdd BLAST60
Domaini2228 – 2285SushiInterPro annotationAdd BLAST58
Domaini2286 – 2343SushiInterPro annotationAdd BLAST58
Domaini2368 – 2427SushiInterPro annotationAdd BLAST60

Keywords - Domaini

SushiPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4297, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155701

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000277_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H2PPD9

Identification of Orthologs from Complete Genome Data

More...OMAi		SPGFCGD

TreeFam database of animal gene trees

More...TreeFami		TF316872

Family and domain databases

Conserved Domains Database

More...CDDi		cd00033, CCP, 22 hits
cd00041, CUB, 9 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.290, 10 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00431, CUB, 9 hits
PF00084, Sushi, 23 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00032, CCP, 23 hits
SM00042, CUB, 9 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49854, SSF49854, 10 hits
SSF57535, SSF57535, 23 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01180, CUB, 9 hits
PS50923, SUSHI, 23 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H2PPD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PGFNAIYQSC FFNFTASSGI ILSPNYPEEY GNNMNCVWLI ISEPGSRIHL 
        60         70         80         90        100
IFNDFDVEPQ FDFLAVKDDG ISDITVLGTF SGNEVPSQLA SSGHIVRLEF 
       110        120        130        140        150
QSDHSTTGRG FNITYTTFGQ NECHDPGIPI NGRRFGDRFL LGSSVSFHCD 
       160        170        180        190        200
DGFVKTQGSE SITCILQDGN VVWSSTVPRC EAPCGGHLTA SSGVILPPGW 
       210        220        230        240        250
PGYYKDSLNC EWIIEAKPGH SIKITFDRFQ TEVNYDTLEV RDGPASSSPL 
       260        270        280        290        300
IGEYHGTQAP QFLISTGNFM YLLFTTDNSR SSIGFLIHYE SVTLESDSCL 
       310        320        330        340        350
DPGIPVNGHR QGGDFGIRST VTFSCDPGYT LSDDEPLICE RNHQWNHALP 
       360        370        380        390        400
SCDALCGGYI QGKSGTVLSP GFPDFYPNSL NCTWTIEVSH GKGVQMIFHT 
       410        420        430        440        450
FHLESSHDYL LITEDGSFSE PVARLTGSVL PHTIKAGLFG NFTAQLRFIS 
       460        470        480        490        500
DFSISYEGFN ITFSEYDLEP CDDPGVASRR IGFHFGVGDS LTFSCFPGYR 
       510        520        530        540        550
LEGATKLTCL GGGRRVWSAP LPRCVAECGA SVKGNEGTLL SPNFPSNYDN 
       560        570        580        590        600
NHECIYKIET EAGKGIHLRA RSFQLFEGDT LKVYDGKDSS SRPLGTFTKN 
       610        620        630        640        650
ELLGLILNST SNHLWLEFNT NGSDTNQGFQ LTYTSFDLVK CEDPGIPNYG 
       660        670        680        690        700
YRIRDEGHFT DTVVLYSCNP GYAMHGSNTL TCLSGDRRVW DKPLPSCIAE 
       710        720        730        740        750
CGGQIHAATS GRILSPGYPA PYDNNLHCTW IIEADPGKTI SLHFIVFDTE 
       760        770        780        790        800
MAHDILKVWD GPVDSDILLK EWSGSALPED IHSTFNSLTL QFDSDFFISK 
       810        820        830        840        850
SGFSIQFSTS IAATCNDPGM PQNGTRYGDS REAGDTVTFQ CDPGYQLQGQ 
       860        870        880        890        900
AKITCVQLNN RFFWQPDPPT CIAACGGNLT GPAGVILSPN YPQPYPPGKE 
       910        920        930        940        950
CDWRVKVNPD FVIALIFKSF NMEPSYDFLH IYEGEDSNSP LIGSYQGSQA 
       960        970        980        990       1000
PERIESSGNS LFLAFRSDAS VGLSGFAIEF KEKPREACFD PGNIMNGTRI 
      1010       1020       1030       1040       1050
GTDFKLGSTI TYQCDSGYKI VDPSSITCVI GVDGKPSWDQ VLPSCNAPCG 
      1060       1070       1080       1090       1100
GQYMGSEGVV LSPNYPHNYT AGQICLYSIT VPKEFVVFGQ FAYFQTALND 
      1110       1120       1130       1140       1150
LAELFDGTHA QARLLSSLSG SHSGETLPLA TSNQILLRFS AKSGASARGF 
      1160       1170       1180       1190       1200
HFVYQGTTVP ALLNSTSNQL YLHFQSDISV AAAGFHLEYK TVGLAACQEP 
      1210       1220       1230       1240       1250
ALPSNSIKIG DRYMVNDVLS FQCEPGYTLQ GRSHISCMPG TVRRWNYPSP 
      1260       1270       1280       1290       1300
LCIATCGGTL STLGGVILSP GFPGSYPNNL DCTWRISLPI GYGAHIQFLN 
      1310       1320       1330       1340       1350
FSTEANHDFL EIQNGPYHTS PMIGQFSGTD LPVALLSTTH ETLVHFYSDH 
      1360       1370       1380       1390       1400
SQNRQGFKLA YQAYELQNCP DPPPFQNGYM VNSDYSVGQS ISFECYPGYI 
      1410       1420       1430       1440       1450
LIGHPVLTCQ HGINRNWNYP FPRCDGDFVK YQCHPGYTLV GTDTLTCKLS 
      1460       1470       1480       1490       1500
SQLQFEGSLP TCEAQCPANE VRTGSSGVIL SPGYPGNYFN SQTCSWSIKV 
      1510       1520       1530       1540       1550
EPNYNITIFV DTFQSEKQFD ALEVFDVPSG QSPLLVVLSG NHTEQSNFTS 
      1560       1570       1580       1590       1600
RSNQLYLRWS TDPYCSLTHP LKNGGILNRT AGAVGSKVHY FCKPGYRMVG 
      1610       1620       1630       1640       1650
HSNATCRRNP LGMYQWDSPT PLCQAVSCGI PESPGNGSFT GNEFTLDSKV 
      1660       1670       1680       1690       1700
VYECHEGFKL ESSQQATAVC QEDGLWSNKG KPPTCKPVAC PSIEAQLSEH 
      1710       1720       1730       1740       1750
VIWRLVSGSL NEYGAQVLLS CSPGYYLEGR RLMQCQANGT WNIGDERPSC 
      1760       1770       1780       1790       1800
RVISCGSLSF PPNGNKIGTL TVYGATAIFT CNTGYTLVGS HVRECLANGL 
      1810       1820       1830       1840       1850
WSGTETRCLA GHCGSPDPIV NGHISGDGFS YRDTVVYQCN PGFRLVGTSV 
      1860       1870       1880       1890       1900
RICLQDHKWS GQTPVCVSIT CGHPGNPAHG FTNGSEFNLN DVVNFTCNTG 
      1910       1920       1930       1940       1950
YLLQGASRAQ CRSNGQWSSP LPTCRVVNCS DPGFVENAIR HGQQNFPESF 
      1960       1970       1980       1990       2000
EYGMSVLYHC KKGFYLLGSS ALTCMANGLW DRSLPKCLAI SCGHPGVPAN 
      2010       2020       2030       2040       2050
AILTGELFTY GAVVHYSCRG SQSLVGNDTR VCQEGSHWSG ALPHCTGNNP 
      2060       2070       2080       2090       2100
GFCGDPGTPA HGSRLGDEFK TKSLLRFSCE MGYQLRGSPE RTCLLNGSWS 
      2110       2120       2130       2140       2150
GLQPVCEAVS CGNPGTPTNG MIVSSDGILF SSSVIYACWE GYKTSGLMTR 
      2160       2170       2180       2190       2200
HCTANGTWTG TAPDCTIISC GDPGTLANGI QFGTDFTFNK TVSYQCNPGY 
      2210       2220       2230       2240       2250
LMEPVTSATI RCTKDGTWNQ SKPVCKAVLC PQPPPVQNGT VEGTDFRWGS 
      2260       2270       2280       2290       2300
SISYSCMDGY QLSHSTILSC EGPGVWKGEI PQCLPVFCGD PGIPAEGRLS 
      2310       2320       2330       2340       2350
GKSFTYKSEV FFQCKSPFIL VGSSRRICQA DGTWSGIQPT CIDPAHNTCP 
      2360       2370       2380       2390       2400
DPGTPHFGIQ NSSRGYEHAC RQPETPAHAD VRAIDLPTFG YTLVYTCHPG 
      2410       2420       2430       2440       2450
FFLAGGSEHR TCKADMKWTG KSPLCKTRPK VQYNGYAGHE NSNGQASFEN 
      2460       2470 
PMYDTNLKPT EAKAVRFDTT LNTVCTVV
Length:2,478
Mass (Da):269,851
Last modified:March 21, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5FDA4BCDB9E89217
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSPPYT00000021332; ENSPPYP00000020508; ENSPPYG00000018313

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000020508

Genome annotation databases

EnsembliENSPPYT00000021332; ENSPPYP00000020508; ENSPPYG00000018313

Phylogenomic databases

eggNOGiKOG4297, Eukaryota
GeneTreeiENSGT00940000155701
HOGENOMiCLU_000277_0_0_1
InParanoidiH2PPD9
OMAiSPGFCGD
TreeFamiTF316872

Family and domain databases

CDDicd00033, CCP, 22 hits
cd00041, CUB, 9 hits
Gene3Di2.60.120.290, 10 hits
InterProiView protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00431, CUB, 9 hits
PF00084, Sushi, 23 hits
SMARTiView protein in SMART
SM00032, CCP, 23 hits
SM00042, CUB, 9 hits
SUPFAMiSSF49854, SSF49854, 10 hits
SSF57535, SSF57535, 23 hits
PROSITEiView protein in PROSITE
PS01180, CUB, 9 hits
PS50923, SUSHI, 23 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH2PPD9_PONAB
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H2PPD9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 7, 2020
This is version 50 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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