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Entry version 50 (07 Oct 2020)
Sequence version 1 (21 Mar 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001595 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi325 ↔ 352PROSITE-ProRule annotation
Disulfide bondi701 ↔ 728PROSITE-ProRule annotation
Disulfide bondi1781 ↔ 1808PROSITE-ProRule annotation
Disulfide bondi1839 ↔ 1866PROSITE-ProRule annotation
Disulfide bondi1897 ↔ 1924PROSITE-ProRule annotation
Disulfide bondi1960 ↔ 1987PROSITE-ProRule annotation
Disulfide bondi2018 ↔ 2045PROSITE-ProRule annotation
Disulfide bondi2079 ↔ 2106PROSITE-ProRule annotation
Disulfide bondi2138 ↔ 2165PROSITE-ProRule annotation
Disulfide bondi2256 ↔ 2283PROSITE-ProRule annotation
Disulfide bondi2314 ↔ 2341PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9601.ENSPPYP00000020508

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 118CUBInterPro annotationAdd BLAST109
Domaini121 – 182SushiInterPro annotationAdd BLAST62
Domaini184 – 292CUBInterPro annotationAdd BLAST109
Domaini297 – 354SushiInterPro annotationAdd BLAST58
Domaini356 – 466CUBInterPro annotationAdd BLAST111
Domaini469 – 526SushiInterPro annotationAdd BLAST58
Domaini528 – 636CUBInterPro annotationAdd BLAST109
Domaini639 – 699SushiInterPro annotationAdd BLAST61
Domaini701 – 810CUBInterPro annotationAdd BLAST110
Domaini813 – 873SushiInterPro annotationAdd BLAST61
Domaini875 – 983CUBInterPro annotationAdd BLAST109
Domaini986 – 1047SushiInterPro annotationAdd BLAST62
Domaini1049 – 1157CUBInterPro annotationAdd BLAST109
Domaini1195 – 1254SushiInterPro annotationAdd BLAST60
Domaini1256 – 1364CUBInterPro annotationAdd BLAST109
Domaini1367 – 1426SushiInterPro annotationAdd BLAST60
Domaini1429 – 1464SushiInterPro annotationAdd BLAST36
Domaini1466 – 1562CUBInterPro annotationAdd BLAST97
Domaini1563 – 1625SushiInterPro annotationAdd BLAST63
Domaini1626 – 1687SushiInterPro annotationAdd BLAST62
Domaini1688 – 1752SushiInterPro annotationAdd BLAST65
Domaini1753 – 1810SushiInterPro annotationAdd BLAST58
Domaini1811 – 1868SushiInterPro annotationAdd BLAST58
Domaini1869 – 1926SushiInterPro annotationAdd BLAST58
Domaini1927 – 1989SushiInterPro annotationAdd BLAST63
Domaini1990 – 2047SushiInterPro annotationAdd BLAST58
Domaini2051 – 2108SushiInterPro annotationAdd BLAST58
Domaini2109 – 2167SushiInterPro annotationAdd BLAST59
Domaini2168 – 2227SushiInterPro annotationAdd BLAST60
Domaini2228 – 2285SushiInterPro annotationAdd BLAST58
Domaini2286 – 2343SushiInterPro annotationAdd BLAST58
Domaini2368 – 2427SushiInterPro annotationAdd BLAST60

Keywords - Domaini

SushiPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4297, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155701

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000277_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H2PPD9

Identification of Orthologs from Complete Genome Data

More...
OMAi
SPGFCGD

TreeFam database of animal gene trees

More...
TreeFami
TF316872

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00033, CCP, 22 hits
cd00041, CUB, 9 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.290, 10 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00431, CUB, 9 hits
PF00084, Sushi, 23 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00032, CCP, 23 hits
SM00042, CUB, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49854, SSF49854, 10 hits
SSF57535, SSF57535, 23 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01180, CUB, 9 hits
PS50923, SUSHI, 23 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H2PPD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PGFNAIYQSC FFNFTASSGI ILSPNYPEEY GNNMNCVWLI ISEPGSRIHL
60 70 80 90 100
IFNDFDVEPQ FDFLAVKDDG ISDITVLGTF SGNEVPSQLA SSGHIVRLEF
110 120 130 140 150
QSDHSTTGRG FNITYTTFGQ NECHDPGIPI NGRRFGDRFL LGSSVSFHCD
160 170 180 190 200
DGFVKTQGSE SITCILQDGN VVWSSTVPRC EAPCGGHLTA SSGVILPPGW
210 220 230 240 250
PGYYKDSLNC EWIIEAKPGH SIKITFDRFQ TEVNYDTLEV RDGPASSSPL
260 270 280 290 300
IGEYHGTQAP QFLISTGNFM YLLFTTDNSR SSIGFLIHYE SVTLESDSCL
310 320 330 340 350
DPGIPVNGHR QGGDFGIRST VTFSCDPGYT LSDDEPLICE RNHQWNHALP
360 370 380 390 400
SCDALCGGYI QGKSGTVLSP GFPDFYPNSL NCTWTIEVSH GKGVQMIFHT
410 420 430 440 450
FHLESSHDYL LITEDGSFSE PVARLTGSVL PHTIKAGLFG NFTAQLRFIS
460 470 480 490 500
DFSISYEGFN ITFSEYDLEP CDDPGVASRR IGFHFGVGDS LTFSCFPGYR
510 520 530 540 550
LEGATKLTCL GGGRRVWSAP LPRCVAECGA SVKGNEGTLL SPNFPSNYDN
560 570 580 590 600
NHECIYKIET EAGKGIHLRA RSFQLFEGDT LKVYDGKDSS SRPLGTFTKN
610 620 630 640 650
ELLGLILNST SNHLWLEFNT NGSDTNQGFQ LTYTSFDLVK CEDPGIPNYG
660 670 680 690 700
YRIRDEGHFT DTVVLYSCNP GYAMHGSNTL TCLSGDRRVW DKPLPSCIAE
710 720 730 740 750
CGGQIHAATS GRILSPGYPA PYDNNLHCTW IIEADPGKTI SLHFIVFDTE
760 770 780 790 800
MAHDILKVWD GPVDSDILLK EWSGSALPED IHSTFNSLTL QFDSDFFISK
810 820 830 840 850
SGFSIQFSTS IAATCNDPGM PQNGTRYGDS REAGDTVTFQ CDPGYQLQGQ
860 870 880 890 900
AKITCVQLNN RFFWQPDPPT CIAACGGNLT GPAGVILSPN YPQPYPPGKE
910 920 930 940 950
CDWRVKVNPD FVIALIFKSF NMEPSYDFLH IYEGEDSNSP LIGSYQGSQA
960 970 980 990 1000
PERIESSGNS LFLAFRSDAS VGLSGFAIEF KEKPREACFD PGNIMNGTRI
1010 1020 1030 1040 1050
GTDFKLGSTI TYQCDSGYKI VDPSSITCVI GVDGKPSWDQ VLPSCNAPCG
1060 1070 1080 1090 1100
GQYMGSEGVV LSPNYPHNYT AGQICLYSIT VPKEFVVFGQ FAYFQTALND
1110 1120 1130 1140 1150
LAELFDGTHA QARLLSSLSG SHSGETLPLA TSNQILLRFS AKSGASARGF
1160 1170 1180 1190 1200
HFVYQGTTVP ALLNSTSNQL YLHFQSDISV AAAGFHLEYK TVGLAACQEP
1210 1220 1230 1240 1250
ALPSNSIKIG DRYMVNDVLS FQCEPGYTLQ GRSHISCMPG TVRRWNYPSP
1260 1270 1280 1290 1300
LCIATCGGTL STLGGVILSP GFPGSYPNNL DCTWRISLPI GYGAHIQFLN
1310 1320 1330 1340 1350
FSTEANHDFL EIQNGPYHTS PMIGQFSGTD LPVALLSTTH ETLVHFYSDH
1360 1370 1380 1390 1400
SQNRQGFKLA YQAYELQNCP DPPPFQNGYM VNSDYSVGQS ISFECYPGYI
1410 1420 1430 1440 1450
LIGHPVLTCQ HGINRNWNYP FPRCDGDFVK YQCHPGYTLV GTDTLTCKLS
1460 1470 1480 1490 1500
SQLQFEGSLP TCEAQCPANE VRTGSSGVIL SPGYPGNYFN SQTCSWSIKV
1510 1520 1530 1540 1550
EPNYNITIFV DTFQSEKQFD ALEVFDVPSG QSPLLVVLSG NHTEQSNFTS
1560 1570 1580 1590 1600
RSNQLYLRWS TDPYCSLTHP LKNGGILNRT AGAVGSKVHY FCKPGYRMVG
1610 1620 1630 1640 1650
HSNATCRRNP LGMYQWDSPT PLCQAVSCGI PESPGNGSFT GNEFTLDSKV
1660 1670 1680 1690 1700
VYECHEGFKL ESSQQATAVC QEDGLWSNKG KPPTCKPVAC PSIEAQLSEH
1710 1720 1730 1740 1750
VIWRLVSGSL NEYGAQVLLS CSPGYYLEGR RLMQCQANGT WNIGDERPSC
1760 1770 1780 1790 1800
RVISCGSLSF PPNGNKIGTL TVYGATAIFT CNTGYTLVGS HVRECLANGL
1810 1820 1830 1840 1850
WSGTETRCLA GHCGSPDPIV NGHISGDGFS YRDTVVYQCN PGFRLVGTSV
1860 1870 1880 1890 1900
RICLQDHKWS GQTPVCVSIT CGHPGNPAHG FTNGSEFNLN DVVNFTCNTG
1910 1920 1930 1940 1950
YLLQGASRAQ CRSNGQWSSP LPTCRVVNCS DPGFVENAIR HGQQNFPESF
1960 1970 1980 1990 2000
EYGMSVLYHC KKGFYLLGSS ALTCMANGLW DRSLPKCLAI SCGHPGVPAN
2010 2020 2030 2040 2050
AILTGELFTY GAVVHYSCRG SQSLVGNDTR VCQEGSHWSG ALPHCTGNNP
2060 2070 2080 2090 2100
GFCGDPGTPA HGSRLGDEFK TKSLLRFSCE MGYQLRGSPE RTCLLNGSWS
2110 2120 2130 2140 2150
GLQPVCEAVS CGNPGTPTNG MIVSSDGILF SSSVIYACWE GYKTSGLMTR
2160 2170 2180 2190 2200
HCTANGTWTG TAPDCTIISC GDPGTLANGI QFGTDFTFNK TVSYQCNPGY
2210 2220 2230 2240 2250
LMEPVTSATI RCTKDGTWNQ SKPVCKAVLC PQPPPVQNGT VEGTDFRWGS
2260 2270 2280 2290 2300
SISYSCMDGY QLSHSTILSC EGPGVWKGEI PQCLPVFCGD PGIPAEGRLS
2310 2320 2330 2340 2350
GKSFTYKSEV FFQCKSPFIL VGSSRRICQA DGTWSGIQPT CIDPAHNTCP
2360 2370 2380 2390 2400
DPGTPHFGIQ NSSRGYEHAC RQPETPAHAD VRAIDLPTFG YTLVYTCHPG
2410 2420 2430 2440 2450
FFLAGGSEHR TCKADMKWTG KSPLCKTRPK VQYNGYAGHE NSNGQASFEN
2460 2470
PMYDTNLKPT EAKAVRFDTT LNTVCTVV
Length:2,478
Mass (Da):269,851
Last modified:March 21, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5FDA4BCDB9E89217
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPPYT00000021332; ENSPPYP00000020508; ENSPPYG00000018313

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000020508

Genome annotation databases

EnsembliENSPPYT00000021332; ENSPPYP00000020508; ENSPPYG00000018313

Phylogenomic databases

eggNOGiKOG4297, Eukaryota
GeneTreeiENSGT00940000155701
HOGENOMiCLU_000277_0_0_1
InParanoidiH2PPD9
OMAiSPGFCGD
TreeFamiTF316872

Family and domain databases

CDDicd00033, CCP, 22 hits
cd00041, CUB, 9 hits
Gene3Di2.60.120.290, 10 hits
InterProiView protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00431, CUB, 9 hits
PF00084, Sushi, 23 hits
SMARTiView protein in SMART
SM00032, CCP, 23 hits
SM00042, CUB, 9 hits
SUPFAMiSSF49854, SSF49854, 10 hits
SSF57535, SSF57535, 23 hits
PROSITEiView protein in PROSITE
PS01180, CUB, 9 hits
PS50923, SUSHI, 23 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH2PPD9_PONAB
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H2PPD9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 7, 2020
This is version 50 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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