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Entry version 51 (11 Dec 2019)
Sequence version 1 (21 Mar 2012)
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Protein

ARID domain-containing protein

Gene
N/A
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ARID domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001595 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9601.ENSPPYP00000019176

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini591 – 682ARIDInterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 405DisorderedSequence analysisAdd BLAST405
Regioni417 – 465DisorderedSequence analysisAdd BLAST49
Regioni486 – 580DisorderedSequence analysisAdd BLAST95
Regioni685 – 789DisorderedSequence analysisAdd BLAST105
Regioni804 – 898DisorderedSequence analysisAdd BLAST95
Regioni930 – 1102DisorderedSequence analysisAdd BLAST173
Regioni1237 – 1307DisorderedSequence analysisAdd BLAST71
Regioni1359 – 1396DisorderedSequence analysisAdd BLAST38
Regioni1409 – 1428DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi17 – 31PolarSequence analysisAdd BLAST15
Compositional biasi58 – 89PolarSequence analysisAdd BLAST32
Compositional biasi101 – 125PolarSequence analysisAdd BLAST25
Compositional biasi161 – 198PolarSequence analysisAdd BLAST38
Compositional biasi213 – 231PolarSequence analysisAdd BLAST19
Compositional biasi241 – 257PolarSequence analysisAdd BLAST17
Compositional biasi267 – 290PolarSequence analysisAdd BLAST24
Compositional biasi298 – 334PolarSequence analysisAdd BLAST37
Compositional biasi346 – 360PolarSequence analysisAdd BLAST15
Compositional biasi380 – 399PolarSequence analysisAdd BLAST20
Compositional biasi425 – 465PolarSequence analysisAdd BLAST41
Compositional biasi514 – 529PolarSequence analysisAdd BLAST16
Compositional biasi539 – 580PolarSequence analysisAdd BLAST42
Compositional biasi697 – 729PolarSequence analysisAdd BLAST33
Compositional biasi745 – 787PolarSequence analysisAdd BLAST43
Compositional biasi818 – 852PolarSequence analysisAdd BLAST35
Compositional biasi974 – 989PolarSequence analysisAdd BLAST16
Compositional biasi1032 – 1060PolarSequence analysisAdd BLAST29
Compositional biasi1069 – 1100PolarSequence analysisAdd BLAST32
Compositional biasi1251 – 1280AcidicSequence analysisAdd BLAST30
Compositional biasi1380 – 1396PolyampholyteSequence analysisAdd BLAST17

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2510 Eukaryota
ENOG410Y034 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155634

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H2PKP8

Identification of Orthologs from Complete Genome Data

More...
OMAi
GQMQQHG

TreeFam database of animal gene trees

More...
TreeFami
TF320364

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038040 ARID1B
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR021906 BAF250/Osa
IPR033388 BAF250_C

The PANTHER Classification System

More...
PANTHERi
PTHR12656 PTHR12656, 1 hit
PTHR12656:SF11 PTHR12656:SF11, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388 ARID, 1 hit
PF12031 BAF250_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501 BRIGHT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774 SSF46774, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011 ARID, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H2PKP8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GSPMDPMVMK RPQLYGMGSN PHSQPQQSSP YPGGSYGPPG PQRYPIGIQG
60 70 80 90 100
RTPGAMGGMQ YPQQQMPPQY GQQGVSGYCQ QGQQPYYSQQ PQPPHLPPQA
110 120 130 140 150
QYLPSQSQQR YQPQQDMSQE GYGTRTQPPL APGKPNHEDL NLIQQERPSS
160 170 180 190 200
LPDLSGSIDD LPTGTEATLS SAVSASGSTS SQGDQSNPAQ SPFSPHASPH
210 220 230 240 250
LSSIPGGPSP SPVGSPVGSN QSRSGPISPA SIPGSQMPPQ PPGSQSESSS
260 270 280 290 300
HPALSQSPMP QERGFMAGTQ RNPQMAQYGP QQTGPSMSPH PSPGGQMHAG
310 320 330 340 350
ISSFQQSNSS GTYGPQMSQY GPQGNYSRPP AYSGVPSASY SGPGPGMGIS
360 370 380 390 400
ANNQMHGQGP SQPCGAVPLG RMPSAGMQNR PFPGNMSSMT PSSPGMSQQG
410 420 430 440 450
GPGMGPPMPT VNRKAQEAAA AVMQAAANSA QSRQGSFPGM NQSGLMASSS
460 470 480 490 500
PYSQPMNNSS SLMNTQAPPY SMAPAMVNSS AASMGLADMM SPGESKLPLP
510 520 530 540 550
LKADGKEGTP QPESKSKDSY SSQGISQPPT PGNLPVPSPM SPSSASISSF
560 570 580 590 600
HGDESDSISS PGWPKTPSSP KSSSSTTTGE KITKVYELGN EPERKLWVDR
610 620 630 640 650
YLTFMEERGS PVSSLPAVGK KPLDLFRLYV CVKEIGGLAQ VNKNKKWREL
660 670 680 690 700
ATNLNVGTSS SAASSLKKQY IQYLFAFECK IERGEEPPPE VFSTGDTKKQ
710 720 730 740 750
PKLQPPSPAN SGSLQGPQTP QSTGSNSMAE VPGDLKPPTP ASTPHGQMTP
760 770 780 790 800
MQGGRSSTIS VHDPFSDVSD SSFPKRNSMT PNAPYQQGMS MPDVMGRMPY
810 820 830 840 850
EPNKDPFGGM RKVPGSSEPF MTQGQMPNSS MQDMYNQSPS GAMSNLGMGQ
860 870 880 890 900
RQQFPYGASY DRRHEPYGQQ YPGQGPPSGQ PPYGGHQPGL YPQQPNYKRH
910 920 930 940 950
MDGMYGPPAK RHEGDMYNMQ YSSQQQEMYN QYGGSYSGPD RRPIQGQYPY
960 970 980 990 1000
PYSRERMQGP GQIQTHGIPP QMMGGPLQSS SSEGPQQNMW AARNDMPYPY
1010 1020 1030 1040 1050
QNRQGPGGPT QAPPYPGMNR TDDMMVPDQR INHESQWPSH VSQRQPYMSS
1060 1070 1080 1090 1100
SASMQPITRP PQPSYQTPPS LPNHISRAPS PASFQRSLEN RMSPSKSPFL
1110 1120 1130 1140 1150
PSMKMQKVMP TVPTSQVTGP PPQPPPIRRE ITFPPGSVEA SQPVLKQRRK
1160 1170 1180 1190 1200
ITSKDIVTPE AWRVMMSLKS GLLAESTWAL DTINILLYDD STVATFNLSQ
1210 1220 1230 1240 1250
LSGFLELLVE YFRKCLIDIF GILTEYEVGD PSQKALDHNA ARKDDSQSLA
1260 1270 1280 1290 1300
DDSGKEEEDA ECIDDDEEDE EDEEEDSEKT ESDEKSSIAL TAPDAAADPK
1310 1320 1330 1340 1350
EKPKQASKFD KLPIKIVKKN NLFVVDRSDK LGRVQEFSSG LLHWQLGGGD
1360 1370 1380 1390 1400
TTEHIQTHFE SKMEIPPRRR PPPPLSSAGR KKEQEGKGDS EEQQEKSIIA
1410 1420 1430 1440 1450
TIDDVLSARP GALPEDANPG PQTESSKFPF GIQQAKSHRN IKLLEDEPRS
1460 1470 1480 1490 1500
RDETPLCTIA HWQDSLAKRC ICVSNIVRSL SFVPGNDAEM SKHPGLVLIL
1510 1520 1530 1540 1550
GKLILLHHEH PERKRAPQTY EKEEDEDKGV ACSKDEWWWD CLEVLRDNTL
1560 1570 1580 1590 1600
VTLANISGQL DLSAYTESIC LPILDGLLHW MVCPSAEAQD PFPTVGPNSV
1610 1620 1630 1640 1650
LSPQRLVLET LCKLSIQDNN VDLILATPPF SRQEKFYATL VRYVGDRKNP
1660 1670 1680 1690 1700
VCREMSMALL SNLAQGDALA ARAIAVQKGS IGNLISFLED GVTMAQYQQS
1710 1720 1730 1740 1750
QHNLMHMQPP PLEPPSVDMM CRAAKALLAM ARVDENRSEF LLHEGRLLDI
1760 1770
SISAVLNSLV ASVICDVLFQ IGQL
Length:1,774
Mass (Da):192,417
Last modified:March 21, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8A6B6EC017168C99
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ABGA01010929 Genomic DNA No translation available.
ABGA01010930 Genomic DNA No translation available.
ABGA01010931 Genomic DNA No translation available.
ABGA01010932 Genomic DNA No translation available.
ABGA01010933 Genomic DNA No translation available.
ABGA01010934 Genomic DNA No translation available.
ABGA01010935 Genomic DNA No translation available.
ABGA01010936 Genomic DNA No translation available.
ABGA01010937 Genomic DNA No translation available.
ABGA01010938 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPPYT00000019931; ENSPPYP00000019176; ENSPPYG00000017126

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01010929 Genomic DNA No translation available.
ABGA01010930 Genomic DNA No translation available.
ABGA01010931 Genomic DNA No translation available.
ABGA01010932 Genomic DNA No translation available.
ABGA01010933 Genomic DNA No translation available.
ABGA01010934 Genomic DNA No translation available.
ABGA01010935 Genomic DNA No translation available.
ABGA01010936 Genomic DNA No translation available.
ABGA01010937 Genomic DNA No translation available.
ABGA01010938 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000019176

Genome annotation databases

EnsembliENSPPYT00000019931; ENSPPYP00000019176; ENSPPYG00000017126

Phylogenomic databases

eggNOGiKOG2510 Eukaryota
ENOG410Y034 LUCA
GeneTreeiENSGT00940000155634
InParanoidiH2PKP8
OMAiGQMQQHG
TreeFamiTF320364

Family and domain databases

Gene3Di1.10.150.60, 1 hit
InterProiView protein in InterPro
IPR038040 ARID1B
IPR001606 ARID_dom
IPR036431 ARID_dom_sf
IPR021906 BAF250/Osa
IPR033388 BAF250_C
PANTHERiPTHR12656 PTHR12656, 1 hit
PTHR12656:SF11 PTHR12656:SF11, 1 hit
PfamiView protein in Pfam
PF01388 ARID, 1 hit
PF12031 BAF250_C, 1 hit
SMARTiView protein in SMART
SM00501 BRIGHT, 1 hit
SUPFAMiSSF46774 SSF46774, 1 hit
PROSITEiView protein in PROSITE
PS51011 ARID, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH2PKP8_PONAB
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H2PKP8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: December 11, 2019
This is version 51 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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