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Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi600 – 674Nuclear receptorPROSITE-ProRule annotationAdd BLAST75

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000016883

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini600 – 674Nuclear receptorInterPro annotationAdd BLAST75
Domaini725 – 961NR LBDInterPro annotationAdd BLAST237

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
InParanoidiH2PEG7
OMAiSKICLVC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

H2PEG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKGYHSLP EGLDMERRWG QVSQAVEHSS LGPTERTDEN NYMEIVNVSC
60 70 80 90 100
VSGAIPNNST QGSSKEKHEL LPCLQQDNNR PGILTSDIKT ELESKELSAT
110 120 130 140 150
VAESMGLYMD SVRDADYSYE QQNQQGSMSP AKIYQNVEQL VKFYKGNGHR
160 170 180 190 200
PSTLSCVNRP LRSFMSDSGS SVNGGVMRAI VKSPIMCHEK SPSVCSPLNM
210 220 230 240 250
TSSVCSPAGI NSVSSTTASF GSFPVHSPIT QGTPLTCSPN VENRGSRSHS
260 270 280 290 300
PAHASNVGSP LSSPLSSMKS SISSPPSHCS VKSPVSSPNN VTLRSSVSSP
310 320 330 340 350
ANINNSRCSV SSPSNTNNRS TLSSPAASTV GSICSPVNNA FSYTASGPSA
360 370 380 390 400
GSSTSRDVVP SPDTQEKGAQ EVPFPKTEEV ESAISNGVTG QLNIVQYIKP
410 420 430 440 450
EPDGAFSSSC LGGNSKINSD SSFSVPIKQE STKHSCSGTS FKGNPTVNPF
460 470 480 490 500
PFMDGSYFSF MDDKDYYSLS GILGPPVPGF DGNCEGSGFP VGIKQEPDDG
510 520 530 540 550
SYYPEASIPS SAIVGVNSGG QSFHYRIGAQ GTISLSRSAR DQSFQHLSSF
560 570 580 590 600
SPVNTLVESW KSHGDLSSRR SDGYPVLEYI PENVSSSTLR SVSTGSSRPS
610 620 630 640 650
KICLVCGDEA SGCHYGVVTC GSCKVFFKRA VEGQHNYLCA GRNDCIDKIR
660 670 680 690 700
RKICPACRLQ KCLQAGMNLG ARKSKKLGKL KGIHEEQPQQ QQPPPPPPPP
710 720 730 740 750
QSPEEGTTYI APAKEPSVNT ALVPQLSTIS RALTPSPVMV LENIEPEIVY
760 770 780 790 800
AGYDSSKPDT AENLLSTLNR LAGKQMIQVV KWAKVLPGFK NLPLEDQITL
810 820 830 840 850
IQYSWMCLSS FALSWRSYKH TNSQFLYFAP DLVFNEEKMH QSAMELQGMH
860 870 880 890 900
QISFQFVRLQ LTFEEYXXIK FLLLLSTIPK DGLKSQAAFE EMRTNYIKEL
910 920 930 940 950
RKMVTKCPNN SGQSWQRFYQ LTKLLDSMHD LVSDLLEFCF YTFRESHALK
960 970 980
VEFPAMLVEI ISDQLPKVES GNAKPLYFHR K
Length:981
Mass (Da):106,792
Last modified:March 21, 2012 - v1
Checksum:iD96C0137EDC9982C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01319249 Genomic DNA No translation available.
ABGA01319250 Genomic DNA No translation available.
ABGA01319251 Genomic DNA No translation available.
ABGA01319252 Genomic DNA No translation available.
ABGA01319253 Genomic DNA No translation available.
ABGA01319254 Genomic DNA No translation available.
ABGA01319255 Genomic DNA No translation available.
ABGA01319256 Genomic DNA No translation available.
ABGA01319257 Genomic DNA No translation available.
ABGA01319258 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSPPYT00000017564; ENSPPYP00000016883; ENSPPYG00000015113

Similar proteinsi

Entry informationi

Entry nameiH2PEG7_PONAB
AccessioniPrimary (citable) accession number: H2PEG7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: June 20, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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