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UniProtKB - H2P1Y0 (H2P1Y0_PONAB)

Entry version 71 (10 Feb 2021)
Sequence version 2 (09 Jan 2013)
Previous versions | rss
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Protein

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma

Gene

PLCG1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+ARBA annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi131 – 142PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseUniRule annotationARBA annotation, TransducerUniRule annotationARBA annotation
Biological processLipid degradationUniRule annotationARBA annotation, Lipid metabolism
LigandCalciumPROSITE-ProRule annotationARBA annotation, Metal-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gammaUniRule annotation (EC:3.1.4.11UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PLCG1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001595 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1188PhosphoserineUniRule annotation1
Modified residuei1215PhosphoserineUniRule annotation1

Keywords - PTMi

PhosphoproteinARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9601.ENSPPYP00000012298

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 108PHInterPro annotationAdd BLAST108
Domaini118 – 153EF-handInterPro annotationAdd BLAST36
Domaini516 – 623SH2InterPro annotationAdd BLAST108
Domaini634 – 722SH2InterPro annotationAdd BLAST89
Domaini757 – 817SH3InterPro annotationAdd BLAST61
Domaini861 – 897PHInterPro annotationAdd BLAST37
Domaini919 – 1036PI-PLC Y-boxInterPro annotationAdd BLAST118
Domaini1041 – 1143C2InterPro annotationAdd BLAST103

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni488 – 510DisorderedSequence analysisAdd BLAST23
Regioni1237 – 1257DisorderedSequence analysisAdd BLAST21

Keywords - Domaini

RepeatARBA annotation, SH2 domainPROSITE-ProRule annotationARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1264, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158901

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002738_5_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H2P1Y0

Identification of Orthologs from Complete Genome Data

More...OMAi		YGGKKQH

Database of Orthologous Groups

More...OrthoDBi		368239at2759

TreeFam database of animal gene trees

More...TreeFami		TF313216

Family and domain databases

Conserved Domains Database

More...CDDi		cd09932, SH2_C-SH2_PLC_gamma_like, 1 hit
cd10341, SH2_N-SH2_PLC_gamma_like, 1 hit
cd11970, SH3_PLCgamma1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.29.30, 1 hit
2.60.40.150, 1 hit
3.20.20.190, 2 hits
3.30.505.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR001192, PI-PLC_fam
IPR016279, PLC-gamma
IPR028380, PLC-gamma1
IPR035023, PLC-gamma_C-SH2
IPR035024, PLC-gamma_N-SH2
IPR017946, PLC-like_Pdiesterase_TIM-brl
IPR035724, PLCgamma1_SH3
IPR000909, PLipase_C_PInositol-sp_X_dom
IPR001711, PLipase_C_Pinositol-sp_Y
IPR000980, SH2
IPR036860, SH2_dom_sf
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain

The PANTHER Classification System

More...PANTHERi		PTHR10336, PTHR10336, 1 hit
PTHR10336:SF173, PTHR10336:SF173, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00168, C2, 1 hit
PF00388, PI-PLC-X, 1 hit
PF00387, PI-PLC-Y, 1 hit
PF00017, SH2, 2 hits
PF00018, SH3_1, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF000952, PLC-gamma, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00390, PHPHLIPASEC
PR00401, SH2DOMAIN
PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00239, C2, 1 hit
SM00233, PH, 3 hits
SM00148, PLCXc, 1 hit
SM00149, PLCYc, 1 hit
SM00252, SH2, 2 hits
SM00326, SH3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47473, SSF47473, 1 hit
SSF50044, SSF50044, 1 hit
SSF51695, SSF51695, 1 hit
SSF55550, SSF55550, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50004, C2, 1 hit
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 1 hit
PS50003, PH_DOMAIN, 2 hits
PS50008, PIPLC_Y_DOMAIN, 1 hit
PS50001, SH2, 2 hits
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H2P1Y0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLFYSKKSQ RPERKTFQVK LETRQITWSR GADKIEGAID IREIKEIRPG 
        60         70         80         90        100
KTSRDFDRYQ EDPAFRPDQS HCFVILYGME FRLKTLSLQA TSEDEVNMWI 
       110        120        130        140        150
KGLTWLMEDT LQAPTPLQIE RWLRKQFYSV DRNREDRISA KDLKNMLSQV 
       160        170        180        190        200
NYRVPNMRFL RERLTDLEQR SGDITYGQFA QLYRSLMYSA QKTMDLPFLE 
       210        220        230        240        250
ASTLRAGERP ELCRVSLPEF QQFLLDYQGE LWAVDRLQVQ EFMLSFLRDP 
       260        270        280        290        300
LREIEEPYFF LDEFVTFLFS KENSVWNSQL DAVCPDTMNN PLSHYWISSS 
       310        320        330        340        350
HNTYLTGDQF SSESSLEAYA RCLRMGCRCI ELDCWDGPDG MPVIYHGHTL 
       360        370        380        390        400
TTKIKFSDVL HTIKEHAFVA SEYPVILSIE DHCSIAQQRN MAQYFKKVLG 
       410        420        430        440        450
DTLLTKPVEI SADGLPSPNQ LKRKILIKHK KLAEGSAYEE VPTSMMYSEN 
       460        470        480        490        500
DISNSIKNGI LYLEDPVNHE WYPHYFVLTS SKIYYSEETS SDQGNEDEEE 
       510        520        530        540        550
PKEVSSSTEL HSNEKWFHGK LGAGRDGRHI AERLLTEYCI ETGAPDGSFL 
       560        570        580        590        600
VRESETFVGD YTLSFWRNGK VQHCRIHSRQ DAGTPKFFLT DNLVFDSLYD 
       610        620        630        640        650
LITHYQQVPL RCNEFEMRLS EPVPQTNAHE SKEWYHASLT RAQAEHMLMR 
       660        670        680        690        700
VPRDGAFLVR KRNEPNSYAI SFRAEGKIKH CRVQQEGQTV MLGNSEFDSL 
       710        720        730        740        750
VDLISYYEKH PLYRKMKLRY PINEEALEKI GTAEPDYGAL YEGRNPGFYV 
       760        770        780        790        800
EANPMPTFKC AVKALFDYKA QREDELTFTK SAIIQNVEKQ EGGWWRGDYG 
       810        820        830        840        850
GKKQLWFPSN YVEEMVNPVA LEPEREHLDE NSPLGDLLRG VLDVPACQIA 
       860        870        880        890        900
IRPEGKNNRL FVFSISMASV AHWSLDVAAD SQEELQDWVK KIREVAQTAD 
       910        920        930        940        950
ARLTEGKIME RRKKIALELS ELVVYCRPVP FDEEKIGTER ACYRDMSSFP 
       960        970        980        990       1000
ETKAEKYVNK VKGKKFLQYN RLQLSRIYPK GQRLDSSNYD PLPMWICGSQ 
      1010       1020       1030       1040       1050
LVALNFQTPD KPMQMNQALF MTGRHCGYVL QPSTMRDEAF DPFDKSSLRG 
      1060       1070       1080       1090       1100
LEPCAISVEV LGARHLPKNG RGIVCPFVEI EVAGAEYDST KQKTEFVVDN 
      1110       1120       1130       1140       1150
GLNPVWPAKP FHFQIINPEF AFLRFVVYEE DMFSDQNFLA QATFPVKGLK 
      1160       1170       1180       1190       1200
TGYRAVPLKN NYSEDLELAS LLIKIDIFPA KQENGDLSPF SGTSLRERGS 
      1210       1220       1230       1240       1250
DASGQLFHGR AREGSFESRY QQPFEDFRIS QEHLTDHFDS RERRAPRRTR 

VNGDNRL
Length:1,257
Mass (Da):145,495
Last modified:January 9, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4CE019BE57A9B7A
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_009231862.1, XM_009233587.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSPPYT00000012779; ENSPPYP00000012298; ENSPPYG00000011011

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100450941

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pon:100450941

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_009231862.1, XM_009233587.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000012298

Genome annotation databases

EnsembliENSPPYT00000012779; ENSPPYP00000012298; ENSPPYG00000011011
GeneIDi100450941
KEGGipon:100450941

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		5335

Phylogenomic databases

eggNOGiKOG1264, Eukaryota
GeneTreeiENSGT00940000158901
HOGENOMiCLU_002738_5_0_1
InParanoidiH2P1Y0
OMAiYGGKKQH
OrthoDBi368239at2759
TreeFamiTF313216

Family and domain databases

CDDicd09932, SH2_C-SH2_PLC_gamma_like, 1 hit
cd10341, SH2_N-SH2_PLC_gamma_like, 1 hit
cd11970, SH3_PLCgamma1, 1 hit
Gene3Di2.30.29.30, 1 hit
2.60.40.150, 1 hit
3.20.20.190, 2 hits
3.30.505.10, 2 hits
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR001192, PI-PLC_fam
IPR016279, PLC-gamma
IPR028380, PLC-gamma1
IPR035023, PLC-gamma_C-SH2
IPR035024, PLC-gamma_N-SH2
IPR017946, PLC-like_Pdiesterase_TIM-brl
IPR035724, PLCgamma1_SH3
IPR000909, PLipase_C_PInositol-sp_X_dom
IPR001711, PLipase_C_Pinositol-sp_Y
IPR000980, SH2
IPR036860, SH2_dom_sf
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
PANTHERiPTHR10336, PTHR10336, 1 hit
PTHR10336:SF173, PTHR10336:SF173, 1 hit
PfamiView protein in Pfam
PF00168, C2, 1 hit
PF00388, PI-PLC-X, 1 hit
PF00387, PI-PLC-Y, 1 hit
PF00017, SH2, 2 hits
PF00018, SH3_1, 1 hit
PIRSFiPIRSF000952, PLC-gamma, 1 hit
PRINTSiPR00390, PHPHLIPASEC
PR00401, SH2DOMAIN
PR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00239, C2, 1 hit
SM00233, PH, 3 hits
SM00148, PLCXc, 1 hit
SM00149, PLCYc, 1 hit
SM00252, SH2, 2 hits
SM00326, SH3, 1 hit
SUPFAMiSSF47473, SSF47473, 1 hit
SSF50044, SSF50044, 1 hit
SSF51695, SSF51695, 1 hit
SSF55550, SSF55550, 2 hits
PROSITEiView protein in PROSITE
PS50004, C2, 1 hit
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 1 hit
PS50003, PH_DOMAIN, 2 hits
PS50008, PIPLC_Y_DOMAIN, 1 hit
PS50001, SH2, 2 hits
PS50002, SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH2P1Y0_PONAB
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H2P1Y0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: January 9, 2013
Last modified: February 10, 2021
This is version 71 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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