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Entry version 48 (02 Jun 2021)
Sequence version 2 (05 Dec 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene

zbed4

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:zbed4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001038 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 23

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8090.ENSORLP00000014542

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini191 – 248BED-typeInterPro annotationAdd BLAST58
Domaini359 – 416BED-typeInterPro annotationAdd BLAST58
Domaini531 – 587BED-typeInterPro annotationAdd BLAST57
Domaini631 – 688BED-typeInterPro annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni90 – 119DisorderedSequence analysisAdd BLAST30
Regioni266 – 310DisorderedSequence analysisAdd BLAST45
Regioni339 – 361DisorderedSequence analysisAdd BLAST23
Regioni582 – 610DisorderedSequence analysisAdd BLAST29
Regioni1109 – 1139DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi104 – 119Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi273 – 304Polar residuesSequence analysisAdd BLAST32

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1121, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161365

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006260_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H2M7T4

Database of Orthologous Groups

More...
OrthoDBi
223749at2759

TreeFam database of animal gene trees

More...
TreeFami
TF322818

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008906, HATC_C_dom
IPR012337, RNaseH-like_sf
IPR003656, Znf_BED
IPR036236, Znf_C2H2_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05699, Dimer_Tnp_hAT, 1 hit
PF02892, zf-BED, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098, SSF53098, 1 hit
SSF57667, SSF57667, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50808, ZF_BED, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H2M7T4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGEEEVPHM SEDLIIESNG LIESKKREAK ATCLKIEGQD GYVFKSYSIH
60 70 80 90 100
PHDDEDPKSL ACSSTLDKDI LPCFHFTSQM DKRLEIDLAC NTGPSSPNTD
110 120 130 140 150
TEGNAETEKY ENGNESSELA REDIEDANEM EDEPQDDERL AFGSSIGPFA
160 170 180 190 200
TKDVDDYSNL LSGYTSTLYD VAMDAVTQSL LSSIRGHANP RKKSPAWNHF
210 220 230 240 250
CISPRDCTKA ICLYCMKEFS RGKNEKDLST SCLMRHVRRA HPTVLLQDGA
260 270 280 290 300
DVSLSNLSSS LPSPFLPFPP SSPKNGDLTN SLFTPASKNS SPSTSSAENS
310 320 330 340 350
DPSSKETLPK VEPKLESCAN ADTVYGSLLP SHSIENNVEE LSDGGSERLP
360 370 380 390 400
GTPKGSNSRR RSAVWKHFYL SPADNSKAVC IHCMNEFSRG KNGKDLGTSC
410 420 430 440 450
LIRHMWRAHK EVVIEENGQG NHIPPPYTNP PSLLSRTQLL DSFEVKKESP
460 470 480 490 500
LLPSSPETIA DELPQSIEES MDIKEECEEV MQFSGQESSL NFFKAQEEDT
510 520 530 540 550
PLTSSPCELF DGPGLSQDHS VFQQNKKIMK RVKSEVWHHF IVSPVDQLKA
560 570 580 590 600
LCRYCPCVIS RGKRGDFGTS CLMRHLTRRH PDVLKNQKST DEKESPPHPY
610 620 630 640 650
NNLATTDTVS AKETEVPVTE AKAQPVPAFS KKTSKLWNHF SISPADPTKV
660 670 680 690 700
VCLHCNRTIS RGKKTTNLGT SCLFRHMQRF HGHVLESNNA ISGDAQDAEI
710 720 730 740 750
HVKQEVMETS VYETEQNCER FDEEHPVAKK ITKLVAEMLA LDLQPSAVVE
760 770 780 790 800
NAGLNRLLEY LKPQYSLPPS SYFTSTAIPD MYEKVKDVVL THLKEAEGGV
810 820 830 840 850
VHFTTSIWVS SQTREYLTLT AHWATYESSV RPQGQDFHCS ALLSVSQIDC
860 870 880 890 900
DQDMHDIPKQ LEYLWDSWIT SSGLKRGFTL TDNITIQHTL EEHGHPIMEC
910 920 930 940 950
FGHTIDLIVS EAIKSQRMVQ NLLSIARKIC ERVHRSAKAK EKLVELQRAH
960 970 980 990 1000
QLPENQLVQD VPSKWRTSFF MLERLVEQKN AIDEMSIECN FREIISCDQW
1010 1020 1030 1040 1050
EVMLSVCNAL KPFEVACREM SNHTATLGQV IPLIHILSRK IDLLFDETVG
1060 1070 1080 1090 1100
IDNMLRSLKE ALVSRMSATL HDQRYTWATM LDPRYKTSLF TEEEAEQCKQ
1110 1120 1130 1140 1150
DLIRELDSSS STSAEAKSLP PNGCSDDPAS HSSSHSNVDD LWSLMPDIRQ
1160 1170 1180 1190 1200
RTKNEEKPKS SEEAVLEYLE EDILDQSCDP LDYWNLKKFL WPDLAKVAAR
1210 1220 1230 1240 1250
YVGCPPSIVP AETLFSTASV NCALNQPRPM LDNIEGLLFL KVNLPLIYFQ

Y
Length:1,251
Mass (Da):140,517
Last modified:December 5, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73A6C12EBEF2F804
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_004082958.1, XM_004082910.2
XP_011489252.1, XM_011490950.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSORLT00000014543; ENSORLP00000014542; ENSORLG00000011603

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101172119

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ola:101172119

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_004082958.1, XM_004082910.2
XP_011489252.1, XM_011490950.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8090.ENSORLP00000014542

Genome annotation databases

EnsembliENSORLT00000014543; ENSORLP00000014542; ENSORLG00000011603
GeneIDi101172119
KEGGiola:101172119

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9889

Phylogenomic databases

eggNOGiKOG1121, Eukaryota
GeneTreeiENSGT00940000161365
HOGENOMiCLU_006260_0_0_1
InParanoidiH2M7T4
OrthoDBi223749at2759
TreeFamiTF322818

Family and domain databases

InterProiView protein in InterPro
IPR008906, HATC_C_dom
IPR012337, RNaseH-like_sf
IPR003656, Znf_BED
IPR036236, Znf_C2H2_sf
PfamiView protein in Pfam
PF05699, Dimer_Tnp_hAT, 1 hit
PF02892, zf-BED, 4 hits
SUPFAMiSSF53098, SSF53098, 1 hit
SSF57667, SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50808, ZF_BED, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH2M7T4_ORYLA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H2M7T4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: December 5, 2018
Last modified: June 2, 2021
This is version 48 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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