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Entry version 59 (13 Nov 2019)
Sequence version 1 (21 Mar 2012)
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Protein

UBX domain-containing protein 3

Gene

ubxn-3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ubiquitin-binding protein which acts as an adapter for ATPase cdc-48.1 and/or cdc-48.2, conferring substrate specificity (PubMed:20977550, PubMed:26842564, PubMed:28368371). Together with ubxn-1 and ubxn-2, plays a role in hermaphrodite spermatogenesis probably by promoting the degradation of sex determination terminal factor tra-1 (PubMed:20977550). During mitosis, ensures the degradation of DNA licensing factor cdt-1 and the disassembly of the DNA replication CMG helicase complex by promoting the dissociation from chromatin of several of its components including cdc-45 and sld-5 (PubMed:26842564, PubMed:28368371).3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Spermatogenesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-6798695 Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UBX domain-containing protein 3Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ubxn-3Imported
ORF Names:F48A11.5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
F48A11.5a ; CE46198 ; WBGene00018586 ; ubxn-3
F48A11.5b ; CE46277 ; WBGene00018586 ; ubxn-3
F48A11.5c ; CE50808 ; WBGene00018586 ; ubxn-3
F48A11.5d ; CE50868 ; WBGene00018586 ; ubxn-3
F48A11.5e ; CE50740 ; WBGene00018586 ; ubxn-3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Causes approximately 30 percent embryonic lethality (PubMed:26842564). RNAi-mediated knockdown does not cause any visible phenotype (PubMed:20977550). Cell division at the 3-cell stage is delayed. In a cdc-48.1 (tm544) mutant background, the delay in cell cycle progression is further enhanced and DNA replication is impaired resulting in the formation of DNA repair rad-51 foci (PubMed:26842564). In addition, cdt-1 degradation and disassembly of cdc-45 and sld-5 from the chromatin during mitosis is impaired (PubMed:26842564). Simultaneous RNAi-mediated knockdown of lrr-1, causes a failure to disassemble components of the CGM helicase complex psf-1, cdc-45 and spd-5 from the chromatin resulting in their abnormal association with chromatin during mitosis (PubMed:28368371). Simultaneous RNAi-mediated knockdown of ubxn-1 and ubxn-2, causes 50 percent embryonic lethality (PubMed:20977550). The surviving hermaphrodite progeny are sterile due to a lack of sperm (PubMed:20977550). Abnormal accumulation of sex determination terminal factor tra-1 (PubMed:20977550). Germline development is normal (PubMed:20977550). In males, sperm production is normal (PubMed:20977550).3 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi582 – 584FPK → NAA or SGG: Prevents interaction with cdc-48 without affecting the interaction with cdt-1 and ubiquitinated protein substrates. 1 Publication3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004443751 – 613UBX domain-containing protein 3Add BLAST613

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
H2L056

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
H2L056

PeptideAtlas

More...
PeptideAtlasi
H2L056

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the germline (at protein level) (PubMed:17498661, PubMed:20977550). Expressed in spermatocytes but not in mature sperm (at protein level) (PubMed:20977550). Expressed in the spermatheca and nerve cells (PubMed:17498661).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in embryos (at protein level) (PubMed:17498661, PubMed:26842564). Also expressed in L4 larvae and adults (PubMed:17498661). Expressed to a lesser extent between L1 and L3 larval stages (PubMed:17498661).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00018586 Expressed in 4 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a complex composed of ubxn-3, cdc-48.1, ufd-1 and npl-4.1 (PubMed:20977550).

Forms a complex composed of ubxn-3, cdc-48.1 and/or cdc-48.2 and substrate cdt-1 (PubMed:26842564).

Interacts (via FPK motif) with cdc-48.1 (via N-terminus) and cdc-48.2 (via N-terminus) (PubMed:20977550, PubMed:26842564).

Interacts (via N-terminus) with cdt-1 and ubiquitinated protein substrates; the interaction is cdc-48-independent (PubMed:26842564). May interact with npl-4.1 (PubMed:20977550).

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.F48A11.5a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
H2L056

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini531 – 610UBXPROSITE-ProRule annotationAdd BLAST80

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili452 – 517Sequence analysisAdd BLAST66

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi582 – 584Interaction with cdc-481 Publication3

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi212 – 216Poly-HisSequence analysis5

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IPG5 Eukaryota
ENOG410Z9BT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154831

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H2L056

KEGG Orthology (KO)

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KOi
K20703

Identification of Orthologs from Complete Genome Data

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OMAi
THRIWTS

Database of Orthologous Groups

More...
OrthoDBi
845154at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01771 UBX_UBXN3A, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.30.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033043 FAF1-like_UBX
IPR036249 Thioredoxin-like_sf
IPR006577 UAS
IPR029071 Ubiquitin-like_domsf
IPR001012 UBX_dom

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00594 UAS, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50033 UBX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform aImported (identifier: H2L056-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDLTASLEDD QREKLRQYTE FTHQQDYEVA IGTLASLNWN LEQAIEAHLM
60 70 80 90 100
QEDKNDDEDP EILETIPAAA SGRNAGASSS SRFEPEVINI EDDEMPATRG
110 120 130 140 150
RRRGRAVTPD ETTTVDNQVK RLRIDDGSSS SSNGAATHHR GAAIPRQKRG
160 170 180 190 200
QATEPTPSSS GSSSASFSSR RGTRANPVPP PNQEPAHPES ARQNGGILAS
210 220 230 240 250
RHNNHNNQQN NHHHHHQRIP INPRRVDVFN VDSDEDDDSM AIAYEDDDDG
260 270 280 290 300
VHEVHHSEVV ARGSGPPNGR IPMIPDGFSS VSDALRNFVA IFSDRFCSTP
310 320 330 340 350
QTQAFMPPFY TEPLPAAVKE AFDHPNSEHR RPLLFYINHD RSIAANIFAS
360 370 380 390 400
QVLCSETVST LIRHQYVLFP WDITSDSNLM LFLEYLQAAN MGDVRTIIQR
410 420 430 440 450
LAMSKIESFP LMAIVVKERN SYRLVDYCRG TDTSDQVMEK LLSGVSEYSD
460 470 480 490 500
IRMNEQSERR EREEREAIRN QQEAEYKASL AADKARMEAK QQEIEEQRLE
510 520 530 540 550
EERKLREEEE ECVRRQTVAS TVPEEPPASA PLAEIINVKF RLPEGGQDMR
560 570 580 590 600
RFRRLESIQT LINYLSSKGY SPDKFKYFNS DFPKKEITRH FDLSHNFADT
610
KWPAREQIFV EEI
Length:613
Mass (Da):69,673
Last modified:March 21, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i120DE35C1516E510
GO
Isoform bImported (identifier: H2L056-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     119-123: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:608
Mass (Da):69,020
Checksum:i80E71F9147C0244D
GO
Isoform cImported (identifier: H2L056-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-94: Missing.
     119-123: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:514
Mass (Da):58,427
Checksum:i73A46DD2217F6D16
GO
Isoform dImported (identifier: H2L056-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-379: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:234
Mass (Da):27,601
Checksum:iDB5C80D3F0741C07
GO
Isoform eImported (identifier: H2L056-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-94: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:519
Mass (Da):59,080
Checksum:i7C82BFAC5DB5A662
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0595921 – 379Missing in isoform d. CuratedAdd BLAST379
Alternative sequenceiVSP_0595931 – 94Missing in isoform c and isoform e. CuratedAdd BLAST94
Alternative sequenceiVSP_059594119 – 123Missing in isoform b and isoform c. Curated5

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CCD71486.1
BX284602 Genomic DNA Translation: CCD71487.1
BX284602 Genomic DNA Translation: CTQ86486.1
BX284602 Genomic DNA Translation: CTQ86487.1
BX284602 Genomic DNA Translation: CTQ86488.1

NCBI Reference Sequences

More...
RefSeqi
NP_001022180.2, NM_001027009.2 [H2L056-1]
NP_001022181.2, NM_001027010.3 [H2L056-2]
NP_001300547.1, NM_001313618.1 [H2L056-3]
NP_001300548.1, NM_001313619.1 [H2L056-4]
NP_001300549.1, NM_001313620.1 [H2L056-5]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F48A11.5a.1; F48A11.5a.1; WBGene00018586 [H2L056-1]
F48A11.5b.1; F48A11.5b.1; WBGene00018586 [H2L056-2]
F48A11.5b.2; F48A11.5b.2; WBGene00018586 [H2L056-2]
F48A11.5c.1; F48A11.5c.1; WBGene00018586 [H2L056-3]
F48A11.5d.1; F48A11.5d.1; WBGene00018586 [H2L056-4]
F48A11.5e.1; F48A11.5e.1; WBGene00018586 [H2L056-5]

Database of genes from NCBI RefSeq genomes

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GeneIDi
173407

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F48A11.5

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CCD71486.1
BX284602 Genomic DNA Translation: CCD71487.1
BX284602 Genomic DNA Translation: CTQ86486.1
BX284602 Genomic DNA Translation: CTQ86487.1
BX284602 Genomic DNA Translation: CTQ86488.1
RefSeqiNP_001022180.2, NM_001027009.2 [H2L056-1]
NP_001022181.2, NM_001027010.3 [H2L056-2]
NP_001300547.1, NM_001313618.1 [H2L056-3]
NP_001300548.1, NM_001313619.1 [H2L056-4]
NP_001300549.1, NM_001313620.1 [H2L056-5]

3D structure databases

SMRiH2L056
ModBaseiSearch...

Protein-protein interaction databases

STRINGi6239.F48A11.5a

Proteomic databases

EPDiH2L056
PaxDbiH2L056
PeptideAtlasiH2L056

Genome annotation databases

EnsemblMetazoaiF48A11.5a.1; F48A11.5a.1; WBGene00018586 [H2L056-1]
F48A11.5b.1; F48A11.5b.1; WBGene00018586 [H2L056-2]
F48A11.5b.2; F48A11.5b.2; WBGene00018586 [H2L056-2]
F48A11.5c.1; F48A11.5c.1; WBGene00018586 [H2L056-3]
F48A11.5d.1; F48A11.5d.1; WBGene00018586 [H2L056-4]
F48A11.5e.1; F48A11.5e.1; WBGene00018586 [H2L056-5]
GeneIDi173407
KEGGicel:CELE_F48A11.5

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
173407
WormBaseiF48A11.5a ; CE46198 ; WBGene00018586 ; ubxn-3
F48A11.5b ; CE46277 ; WBGene00018586 ; ubxn-3
F48A11.5c ; CE50808 ; WBGene00018586 ; ubxn-3
F48A11.5d ; CE50868 ; WBGene00018586 ; ubxn-3
F48A11.5e ; CE50740 ; WBGene00018586 ; ubxn-3

Phylogenomic databases

eggNOGiENOG410IPG5 Eukaryota
ENOG410Z9BT LUCA
GeneTreeiENSGT00940000154831
InParanoidiH2L056
KOiK20703
OMAiTHRIWTS
OrthoDBi845154at2759

Enzyme and pathway databases

ReactomeiR-CEL-6798695 Neutrophil degranulation

Gene expression databases

BgeeiWBGene00018586 Expressed in 4 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd01771 UBX_UBXN3A, 1 hit
Gene3Di3.40.30.10, 1 hit
InterProiView protein in InterPro
IPR033043 FAF1-like_UBX
IPR036249 Thioredoxin-like_sf
IPR006577 UAS
IPR029071 Ubiquitin-like_domsf
IPR001012 UBX_dom
SMARTiView protein in SMART
SM00594 UAS, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50033 UBX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBXN3_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H2L056
Secondary accession number(s): A0A0K3ARL0
, A0A0K3ATZ0, A0A0K3AWX1, Q6A589
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2018
Last sequence update: March 21, 2012
Last modified: November 13, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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