Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Acyl CoA DeHydrogenase

Gene

acdh-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

  • defense response to Gram-negative bacterium Source: WormBase
  • innate immune response Source: WormBase

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

ReactomeiR-CEL-70895 Branched-chain amino acid catabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Acyl CoA DeHydrogenaseImported
Gene namesi
Name:acdh-1Imported
ORF Names:C55B7.4Imported, CELE_C55B7.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC55B7.4a ; CE09015 ; WBGene00016943 ; acdh-1

PTM / Processingi

Proteomic databases

EPDiH2KZG6
PaxDbiH2KZG6
PeptideAtlasiH2KZG6

Expressioni

Gene expression databases

BgeeiWBGene00016943 Expressed in 5 organ(s), highest expression level in adult organism

Interactioni

Protein-protein interaction databases

IntActiH2KZG6, 3 interactors
STRINGi6239.C55B7.4a

Structurei

3D structure databases

ProteinModelPortaliH2KZG6
SMRiH2KZG6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 159Acyl-CoA_dh_NInterPro annotationAdd BLAST111
Domaini164 – 259Acyl-CoA_dh_MInterPro annotationAdd BLAST96
Domaini271 – 417Acyl-CoA_dh_1InterPro annotationAdd BLAST147

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili320 – 340Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0139 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00760000119007
InParanoidiH2KZG6
KOiK09478
OMAiFITNGTW
OrthoDBiEOG091G04BS
PhylomeDBiH2KZG6

Family and domain databases

Gene3Di1.10.540.10, 1 hit
InterProiView protein in InterPro
IPR006089 Acyl-CoA_DH_CS
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR013786 AcylCoA_DH/ox_N
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF00441 Acyl-CoA_dh_1, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PF02771 Acyl-CoA_dh_N, 1 hit
SUPFAMiSSF47203 SSF47203, 1 hit
SSF56645 SSF56645, 1 hit
PROSITEiView protein in PROSITE
PS00072 ACYL_COA_DH_1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

H2KZG6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTSTTKILK QAMNIISTIR SSYSTATAVS ISRHCEDFTG TPPPVNLLTE
60 70 80 90 100
NELFFADTVR KFSKDVVKPL VREMDKYSKM SPIVTQGVFE NGLMGVHVPE
110 120 130 140 150
EYGGSGSSFF NAMIVIEELA KTDPSVSAMV GIHNTLPVSM IIDYGTEEQK
160 170 180 190 200
LKYLPRLCSD SLASFCISES GAGSDAFALK TIAKRDGDHF LISGTKMWIT
210 220 230 240 250
NSGEAQVFVV FANADPSQKY KGITCFIVER SADGLTVDKE EDKLGIRASS
260 270 280 290 300
TCQVHFDNVR VHKSAILGEY GKGYKYAIEC LNAGRIAIGA QMIGLAQGCF
310 320 330 340 350
DQTIPYLQQR EQFGQRLIDF QGLQHQIAQA RTEIEAARLL VYNAARMKEY
360 370 380 390 400
GIPYVREAAM AKLFASQVAT STSAQCVKWL GGVGFTKEFP AEKFYRDAMI
410 420
GEIYEGTSNI QLNTIAKLID NEYKWKN
Length:427
Mass (Da):47,148
Last modified:March 21, 2012 - v1
Checksum:iF0C4FABAC9839EE2
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8IAB6Q8IAB6_CAEEL
Acyl CoA DeHydrogenase
acdh-1 C55B7.4, CELE_C55B7.4
252Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CCD68091.1
RefSeqiNP_491871.1, NM_059470.4
UniGeneiCel.5996

Genome annotation databases

EnsemblMetazoaiC55B7.4a; C55B7.4a; WBGene00016943
GeneIDi172358
KEGGicel:CELE_C55B7.4

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CCD68091.1
RefSeqiNP_491871.1, NM_059470.4
UniGeneiCel.5996

3D structure databases

ProteinModelPortaliH2KZG6
SMRiH2KZG6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiH2KZG6, 3 interactors
STRINGi6239.C55B7.4a

Proteomic databases

EPDiH2KZG6
PaxDbiH2KZG6
PeptideAtlasiH2KZG6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC55B7.4a; C55B7.4a; WBGene00016943
GeneIDi172358
KEGGicel:CELE_C55B7.4

Organism-specific databases

CTDi172358
WormBaseiC55B7.4a ; CE09015 ; WBGene00016943 ; acdh-1

Phylogenomic databases

eggNOGiKOG0139 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00760000119007
InParanoidiH2KZG6
KOiK09478
OMAiFITNGTW
OrthoDBiEOG091G04BS
PhylomeDBiH2KZG6

Enzyme and pathway databases

ReactomeiR-CEL-70895 Branched-chain amino acid catabolism

Gene expression databases

BgeeiWBGene00016943 Expressed in 5 organ(s), highest expression level in adult organism

Family and domain databases

Gene3Di1.10.540.10, 1 hit
InterProiView protein in InterPro
IPR006089 Acyl-CoA_DH_CS
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR013786 AcylCoA_DH/ox_N
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF00441 Acyl-CoA_dh_1, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PF02771 Acyl-CoA_dh_N, 1 hit
SUPFAMiSSF47203 SSF47203, 1 hit
SSF56645 SSF56645, 1 hit
PROSITEiView protein in PROSITE
PS00072 ACYL_COA_DH_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH2KZG6_CAEEL
AccessioniPrimary (citable) accession number: H2KZG6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2012
Last sequence update: March 21, 2012
Last modified: October 10, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again