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UniProtKB - H0ZLT1 (H0ZLT1_TAEGU)

Entry version 56 (07 Oct 2020)
Sequence version 2 (17 Jun 2020)
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Protein
Submitted name:

Uncharacterized protein

Gene

MIDEAS

Organism
Taeniopygia guttata (Zebra finch) (Poephila guttata)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MIDEASImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTaeniopygia guttata (Zebra finch) (Poephila guttata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri59729 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Passeriformes › Passeroidea › Estrildidae › Estrildinae › Taeniopygia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007754 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini733 – 825ELM2InterPro annotationAdd BLAST93
Domaini840 – 891SANTInterPro annotationAdd BLAST52
Domaini1040 – 1067C2H2-typeInterPro annotationAdd BLAST28

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni414 – 461DisorderedSequence analysisAdd BLAST48
Regioni550 – 624DisorderedSequence analysisAdd BLAST75
Regioni938 – 1041DisorderedSequence analysisAdd BLAST104
Regioni1054 – 1115DisorderedSequence analysisAdd BLAST62

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili162 – 182Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi423 – 438PolyampholyteSequence analysisAdd BLAST16
Compositional biasi439 – 456PolarSequence analysisAdd BLAST18
Compositional biasi550 – 580PolyampholyteSequence analysisAdd BLAST31
Compositional biasi596 – 617PolyampholyteSequence analysisAdd BLAST22
Compositional biasi941 – 956AcidicSequence analysisAdd BLAST16
Compositional biasi957 – 971PolyampholyteSequence analysisAdd BLAST15
Compositional biasi977 – 992PolarSequence analysisAdd BLAST16
Compositional biasi993 – 1007PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1057 – 1074PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1087 – 1115PolarSequence analysisAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157459

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		H0ZLT1

Identification of Orthologs from Complete Genome Data

More...OMAi		FHVAKKP

TreeFam database of animal gene trees

More...TreeFami		TF106431

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01448, ELM2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46689, SSF46689, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H0ZLT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLQAQQKSS SKRTGKRVAY FNEQDIAVPS KEPQQQLKEG QYYGHGGNIP 
        60         70         80         90        100
VSQTMEISHP GGLTSAPNNV ALMNSVYNQD RGESVMMPQS VTAVKWQNSL 
       110        120        130        140        150
MGNRLPERGD SHWQSPPSMW NHSMVFGGNP KGPHSNAGAP GFYGHPEALK 
       160        170        180        190        200
RNQEKGVFVS QLDLYGDAVQ QMMSQKAQLE QQALVRQQAQ MNSFHQMQKQ 
       210        220        230        240        250
QQQNQTLPLQ PFQLAFGHQG QKQGLPELLH VFQEAPTSSS PAFTAQQKQQ 
       260        270        280        290        300
ALPQLQLFEN FYPQQQQQHQ QQTATQAFGL QQTTSIAQPH VAAAAPQHHM 
       310        320        330        340        350
MPHQFQQAER NQELFKALTE QNQQAVLPQT QIPFPRRSRR LSKEGGLLTS 
       360        370        380        390        400
AGEVLTSKQA EQPPSNLFLH HWQTHQQEVP LQQTPESLAH SKSGYLHPKR 
       410        420        430        440        450
LDLGQKDVLV NSEQCQKETD RQAAAQNGRD EEKQAAAPEE NTQRTNDFQS 
       460        470        480        490        500
VRGGVIQSTR RRRRVSQEAN LLTLAQKAVE LASLQNVKEL DNSEEKKSVL 
       510        520        530        540        550
VTAPGPTAAS KSVVEFAGSS PAPKKAREDN SLVPLIIPVS VPVRKIDLQS 
       560        570        580        590        600
LEKEKSEDGK LQRGQANDRA PCERKPSVIV TRRRSNRNNM ETSSQHEDAV 
       610        620        630        640        650
PKDEAEGFAR KPKQRPRPEP LFIPPKAGTF IAPPVYSNIT PYQSHLRSPV 
       660        670        680        690        700
RLADHPSDRN FELPPYTPPP ILSPVREGSG LYFNAILSSS GHSVAPPMTP 
       710        720        730        740        750
KSGHRTLLRS NSSEVTPPIL TVVGEATPVS IEPRINVGTR FQAEIPSLQD 
       760        770        780        790        800
RSLAEADEHK AELVWQPWGD LETNKVTQEN VENLLAAACS SIFPGAGTNQ 
       810        820        830        840        850
ELALHFLHEE KGSILGALTK LLLKKPVRPP SHPLADYHYT GSDKWKVGEK 
       860        870        880        890        900
KLFNKGIAIY KKDFFLVQKL IKTKTVAQCV EFYYTYKKQV KIGRNGTLIF 
       910        920        930        940        950
GDIDGASERS MKDEAEVDIK SSHRFARVLP LRRDIFSEEH GHVEEEEEEE 
       960        970        980        990       1000
EEEEAEEGLD NRKRSADALK DEQTLQDGVM ASDTNMRSHE STVTGRTGRK 
      1010       1020       1030       1040       1050
PRETTMKPRK PITAPVQRKK RKQKMKPDAT SKTQNTENTF PCKKCGRVFY 
      1060       1070       1080       1090       1100
KVKSRSAHMK SHAEQEKKAA ALKQQEKEAA AAAAARSQAQ QEESSDSGSS 
      1110 
SSGSSSASSD EDGEI
Length:1,115
Mass (Da):124,169
Last modified:June 17, 2020 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0ED20C733D4BFC1B
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_012429341.1, XM_012573887.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSTGUT00000011679; ENSTGUP00000011554; ENSTGUG00000011205

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100223903

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_012429341.1, XM_012573887.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSTGUT00000011679; ENSTGUP00000011554; ENSTGUG00000011205
GeneIDi100223903

Phylogenomic databases

GeneTreeiENSGT00940000157459
InParanoidiH0ZLT1
OMAiFHVAKKP
TreeFamiTF106431

Family and domain databases

InterProiView protein in InterPro
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01448, ELM2, 1 hit
SMARTiView protein in SMART
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0ZLT1_TAEGU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0ZLT1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: June 17, 2020
Last modified: October 7, 2020
This is version 56 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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