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Entry version 58 (16 Jan 2019)
Sequence version 1 (22 Feb 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Taeniopygia guttata (Zebra finch) (Poephila guttata)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi677 – 684ATPPROSITE-ProRule annotation8
Nucleotide bindingi1340 – 1347ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-TGU-382556 ABC-family proteins mediated transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTaeniopygia guttata (Zebra finch) (Poephila guttata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri59729 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePasseriformesPasseroideaEstrildidaeEstrildinaeTaeniopygia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007754 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei30 – 48HelicalSequence analysisAdd BLAST19
Transmembranei69 – 88HelicalSequence analysisAdd BLAST20
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Transmembranei164 – 187HelicalSequence analysisAdd BLAST24
Transmembranei326 – 345HelicalSequence analysisAdd BLAST20
Transmembranei365 – 383HelicalSequence analysisAdd BLAST19
Transmembranei439 – 462HelicalSequence analysisAdd BLAST24
Transmembranei468 – 487HelicalSequence analysisAdd BLAST20
Transmembranei550 – 573HelicalSequence analysisAdd BLAST24
Transmembranei593 – 613HelicalSequence analysisAdd BLAST21
Transmembranei976 – 999HelicalSequence analysisAdd BLAST24
Transmembranei1030 – 1052HelicalSequence analysisAdd BLAST23
Transmembranei1105 – 1122HelicalSequence analysisAdd BLAST18
Transmembranei1128 – 1148HelicalSequence analysisAdd BLAST21
Transmembranei1219 – 1239HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
59729.ENSTGUP00000009632

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini328 – 610ABC transmembrane type-1InterPro annotationAdd BLAST283
Domaini643 – 867ABC transporterInterPro annotationAdd BLAST225
Domaini986 – 1270ABC transmembrane type-1InterPro annotationAdd BLAST285
Domaini1306 – 1540ABC transporterInterPro annotationAdd BLAST235

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili254 – 274Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0054 Eukaryota
COG1132 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164383

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H0ZGC0

Identification of Orthologs from Complete Genome Data

More...
OMAi
NMKNKDK

TreeFam database of animal gene trees

More...
TreeFami
TF105199

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030247 ABCC2
IPR005292 Multidrug-R_assoc
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR24223:SF176 PTHR24223:SF176, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00957 MRP_assoc_pro, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H0ZGC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LEKFCGSVFW NDSYLARPDA DLPVCFQQTV LVWIPLGFFW ILAPWQLLPM
60 70 80 90 100
VEKLSPGHFP QMGCPLSPQV LAALLVLTAV AELALAFVDA EQGAVPAVQY
110 120 130 140 150
TNPSLYLATW IMVLLVQDAR RFCLRRDSGV LFCFWILTLL CGILPFQSLV
160 170 180 190 200
RKALQEPISD LPRFILFFIS YGLQLLLFLV SGFSDIAPET KEIGKKNPEV
210 220 230 240 250
TASFLSCVTF QWYSSMVFKG YRKPLEIEDV WELKDEDKTK ALYTAFEKNM
260 270 280 290 300
KTAMQKARAE LEKRKCKKRR QEGDPDHGNS MSKAQSQDIL VLRQPKKKKK
310 320 330 340 350
KKGDNEDSDY PKGWLMKTLA KTFQQNLLLA VAFKVVHDAL VFVSPQLLKL
360 370 380 390 400
LIAFVSDEDS FAWQGYLYAI LLFLAAVIQS LCLQQHFSLC FQLGINVRAS
410 420 430 440 450
LIAAIYKKSL TMSGATRKES TVGETVNLMS ADAQRFMDLA NFIHQLWSSP
460 470 480 490 500
LQIILSIVFL WGELGPSVLA GIATLLLLLP INAFLVAKAK TIQERNMKNK
510 520 530 540 550
DERMKIMTEI LNGIKILKLF AWEPSFEKRV NEIRAHELKN LVNFSYLQSV
560 570 580 590 600
SVFVFTCAPF LVSLPLFAVY VFVYENNILD AQKAFTAISL FNVLRFPMAT
610 620 630 640 650
LPMVISFLVQ ANVSTARLER YLSGEDLDTS AIHHNPIAGR RTSRLLPATF
660 670 680 690 700
AWEQDGNAAI RDVTLDIMPG SLVAVVGAVG SGKSSLVSAM LGEMENIKGH
710 720 730 740 750
INIQGSLAYV PQQAWIQNAT LKDNIIFGSE LDEARYQQVL KACALLPDLE
760 770 780 790 800
LLPAGDQTEI GEKGINLSGG QKQRVSLARA VYSNADIYIL DDPLSAVDAH
810 820 830 840 850
VGKYLFEHVL GPKGLLQKKT RILVTHSISF LPQVDNIVVL AAGAVSEHGS
860 870 880 890 900
YSTLLANKGA FSQFLNLYWE HSGAVGESVI RAGDEEEADE AVDPCTEERT
910 920 930 940 950
EDVVTMTLKR EASIHRRKLS RRLFSRGIHY HHLSKNSTSS QKKAQEEPPK
960 970 980 990 1000
KLKGQQLIEK EAVETGRVKF SMYLRYLRAV GLCFTFWIVM GYVGQYAAYV
1010 1020 1030 1040 1050
GSNLWLSDWT DDSVRYQNQT YPTQQRDLRI GVFGALGVSQ ALFLLFATML
1060 1070 1080 1090 1100
SARGTVRASR VMHQQLLSNI LRAPMSFFDT TPIGRIVNRF AKDIFTVDET
1110 1120 1130 1140 1150
IPMSFRSWIS CFMAIISTLI VICLATPFFA VVIIPLSIFY YFVLRFYVST
1160 1170 1180 1190 1200
SRQLRRLDSV TRSPIYSHFG ETVSGLSVIR AYGHQERFLK QNEITMDINQ
1210 1220 1230 1240 1250
KSVYSWIVSN RWLAIRLEFV GSLVVFFSAL LAVIAKGTLE GGIVGLSVSS
1260 1270 1280 1290 1300
ALNVTQTLNW LVRTSSELET NIVAVERVHE YMTVKNEAPW VTKKRPPHGW
1310 1320 1330 1340 1350
PSRGEIQFVD YKVRYRPELD LVLQGITCDI GSTEKVGVVG RTGAGKSSLT
1360 1370 1380 1390 1400
NCLFRVLEAA GGKIIIDDVD IATIGLHDLR KSLTIIPQDP VLFTGTLRMN
1410 1420 1430 1440 1450
LDPFDQYSDE EVWKALELAH LKTFVQGLPE RLLHLVSEAG ENLSVGQRQL
1460 1470 1480 1490 1500
VCLARALLRK AKILILDEAT AAVDLETDHL IQTTIRSAFA DCTVLTIAHR
1510 1520 1530 1540 1550
LHTIMDSNRV MVLHAGQIVE FDSPEQLLMK QGIFSAMAKD AGITAAESTA

L
Length:1,551
Mass (Da):173,539
Last modified:February 22, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAAB5AEDFF07B7421
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ABQF01027216 Genomic DNA No translation available.
ABQF01027217 Genomic DNA No translation available.
ABQF01027218 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSTGUT00000009735; ENSTGUP00000009632; ENSTGUG00000009186

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABQF01027216 Genomic DNA No translation available.
ABQF01027217 Genomic DNA No translation available.
ABQF01027218 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi59729.ENSTGUP00000009632

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTGUT00000009735; ENSTGUP00000009632; ENSTGUG00000009186

Phylogenomic databases

eggNOGiKOG0054 Eukaryota
COG1132 LUCA
GeneTreeiENSGT00940000164383
InParanoidiH0ZGC0
OMAiNMKNKDK
TreeFamiTF105199

Enzyme and pathway databases

ReactomeiR-TGU-382556 ABC-family proteins mediated transport

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030247 ABCC2
IPR005292 Multidrug-R_assoc
IPR027417 P-loop_NTPase
PANTHERiPTHR24223:SF176 PTHR24223:SF176, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
TIGRFAMsiTIGR00957 MRP_assoc_pro, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0ZGC0_TAEGU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0ZGC0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 16, 2019
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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