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Entry version 52 (12 Aug 2020)
Sequence version 2 (17 Jun 2020)
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Protein
Submitted name:

Arginine-glutamic acid dipeptide repeats

Gene

RERE

Organism
Taeniopygia guttata (Zebra finch) (Poephila guttata)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Arginine-glutamic acid dipeptide repeatsImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:REREImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTaeniopygia guttata (Zebra finch) (Poephila guttata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri59729 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePasseriformesPasseroideaEstrildidaeEstrildinaeTaeniopygia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007754 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

AcetylationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini103 – 270BAHInterPro annotationAdd BLAST168
Domaini271 – 374ELM2InterPro annotationAdd BLAST104
Domaini378 – 430SANTInterPro annotationAdd BLAST53

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 90DisorderedSequence analysisAdd BLAST90
Regioni451 – 481DisorderedSequence analysisAdd BLAST31
Regioni529 – 1095DisorderedSequence analysisAdd BLAST567
Regioni1144 – 1214DisorderedSequence analysisAdd BLAST71

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 38PolyampholyteSequence analysisAdd BLAST38
Compositional biasi50 – 75PolyampholyteSequence analysisAdd BLAST26
Compositional biasi451 – 473PolarSequence analysisAdd BLAST23
Compositional biasi543 – 558PolyampholyteSequence analysisAdd BLAST16
Compositional biasi593 – 613PolarSequence analysisAdd BLAST21
Compositional biasi614 – 657PolyampholyteSequence analysisAdd BLAST44
Compositional biasi658 – 672PolarSequence analysisAdd BLAST15
Compositional biasi673 – 696PolyampholyteSequence analysisAdd BLAST24
Compositional biasi697 – 738PolarSequence analysisAdd BLAST42
Compositional biasi745 – 781Pro-richSequence analysisAdd BLAST37
Compositional biasi790 – 807Pro-richSequence analysisAdd BLAST18
Compositional biasi840 – 881PolarSequence analysisAdd BLAST42
Compositional biasi882 – 919Pro-richSequence analysisAdd BLAST38
Compositional biasi962 – 977PolarSequence analysisAdd BLAST16
Compositional biasi1005 – 1033Pro-richSequence analysisAdd BLAST29
Compositional biasi1034 – 1051PolarSequence analysisAdd BLAST18
Compositional biasi1144 – 1178PolyampholyteSequence analysisAdd BLAST35

Keywords - Domaini

Zinc-fingerARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153615

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005292_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H0Z0G7

Identification of Orthologs from Complete Genome Data

More...
OMAi
PCRRLNS

TreeFam database of animal gene trees

More...
TreeFami
TF328554

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00202, ZnF_GATA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.490, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002951, Atrophin-like
IPR001025, BAH_dom
IPR043151, BAH_sf
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03154, Atrophin-1, 1 hit
PF01426, BAH, 1 hit
PF01448, ELM2, 1 hit
PF00320, GATA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00439, BAH, 1 hit
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51038, BAH, 1 hit
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

H0Z0G7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTADKEKDKD KEKDRDRDRD KERDKRDKAR ESENSRPRRS CTLEGGAKNY
60 70 80 90 100
AESEHSEDED NDNNSATTEE STKKSKKKPP KKKSRYERTD NGEITSFITE
110 120 130 140 150
DDVVYRPGDC VYIESRRPNT PYFICSIQDF KLVRNIFTSP PFPAPGSRVG
160 170 180 190 200
IFLSSSEVVL QSKRDHLLMN VKWYYRQSEV PDSVYQHLVQ DRHNENDSGR
210 220 230 240 250
ELVITDPVIK NRELFISDYV DTYHAAALRG KCNISHFSDI FAAREFKARV
260 270 280 290 300
DSFFYILGYN PETRRLNSTQ GEIRVGPSHQ AKLPDLQPFP SPDGDTVTQH
310 320 330 340 350
EELVWMPGVN DCDLLMYLRA ARSMAAFAGM CDGGSTEDGC VAASRDDTTL
360 370 380 390 400
NALNTLHESN YDAGKALQRL VKKPVPKLIE KCWTEDEVKR FIKGLRQYGK
410 420 430 440 450
NFFRIRKELL PNKETGELIT FYYYWKKTPE AASSRAHRRH RRQAVFRRIK
460 470 480 490 500
TRTASTPVNT PSRPPSSEFL DLSSASEDDF DSEDSEQELK GYACRHCFTT
510 520 530 540 550
TSKDWHHGGR ENILLCTDCR IHFKKYGELP PIEKPVDPPP FMFKPVKEED
560 570 580 590 600
DGLSGKHSMR TRRSRGSMST LRSGRKKQAA SPDGRASPIA EDVRSSGRNS
610 620 630 640 650
PSAASTSSND SKAESVKKST KKIKEEVSSP LKNSKRQREK AASDTEEPDR
660 670 680 690 700
SNAKKSKTQE ISRPNSPSEG EGEGESSDSR SVNDEGSSDP KDIDQDNRST
710 720 730 740 750
SPSIPSPQDN ESDSDSSAQQ QVLQAQPQAL QAPSGGSAQA AAATPPVPAP
760 770 780 790 800
LPAPSAAPAP AQASPPASQP SGQPQPPAPL SHIQQAPALH PPRLPSPHPP
810 820 830 840 850
LQPLSPHAQP PLHGTAAPAP HGLQAQPLLP HAGPAQPFSL PAQPAQSQVP
860 870 880 890 900
LQTQAPSHPH SGLQVTQPVL PSGASLQQAQ PPREQPLPPA PMAMPHIKPP
910 920 930 940 950
PTTPIPQLPA APAHKHPPHL SGPSPFSMNS NLPPPPALKP LSSLSTHHPP
960 970 980 990 1000
SAHPPPLQLM PQSQPLQSSQ AQPPVLTQSQ SLPPPASHPP SALHQVSSQP
1010 1020 1030 1040 1050
PFSQHPFVPG GPPSITPPSC PSTSTPPTVP GIPLQTPIST SAASSGTVPV
1060 1070 1080 1090 1100
VTACTLPPIQ IKEEVPDEAE EPESPPPPPR SPSPEPTVVD IPSHASQSAR
1110 1120 1130 1140 1150
FYKHLDRGYN SCSRADLYFM PLAGSKLAKK REEAIEKAKR EAEQKAREER
1160 1170 1180 1190 1200
EREKEKEKER EREREREREA ERAAKVSSSS HEGRLGESQL SGPAHMRPSF
1210 1220 1230 1240 1250
EPPPTTIAAV PPYIGPDTPA LRTLSEYARP HVMSPTNRNH PFFVPLNPTD
1260 1270 1280 1290 1300
PLLAYHMPGL YNVDPTIRER ELREREIRER EIRERELRER MKPGFEVKPP
1310 1320 1330 1340 1350
ELDALHPATN PMEHFARHGA LTIPPTAGPH PFASFHPGLN PLERERLALA
1360 1370 1380 1390 1400
GPQLRPEMSY PDRLAAERIH AERMASLTND PLARLQMFNV TPHHHQHSHI
1410 1420 1430 1440 1450
HSHLHLHQQD PLHQGSAGPV HPLVDPLAAG PHLARFPYPP GTIPNPLLGQ
1460 1470 1480 1490 1500
PPHEHEMLRH PVFGTPYPRD LPGAIPPPMS AAHQLQAMHA QSAELQRLAM
1510 1520 1530
EQQWLHGHPH MHGGHLPSQE DYYSRLKKEG DKQL
Length:1,534
Mass (Da):169,698
Last modified:June 17, 2020 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i46AC4D924F1425F9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A674GB21A0A674GB21_TAEGU
Arginine-glutamic acid dipeptide re...
RERE
1,546Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A674GDD7A0A674GDD7_TAEGU
Arginine-glutamic acid dipeptide re...
RERE
1,532Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A674GF62A0A674GF62_TAEGU
Arginine-glutamic acid dipeptide re...
RERE
1,287Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A674HFQ7A0A674HFQ7_TAEGU
Arginine-glutamic acid dipeptide re...
RERE
559Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A674HNM0A0A674HNM0_TAEGU
Arginine-glutamic acid dipeptide re...
RERE
1,224Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSTGUT00000004099; ENSTGUP00000004054; ENSTGUG00000003924

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSTGUT00000004099; ENSTGUP00000004054; ENSTGUG00000003924

Phylogenomic databases

GeneTreeiENSGT00940000153615
HOGENOMiCLU_005292_1_0_1
InParanoidiH0Z0G7
OMAiPCRRLNS
TreeFamiTF328554

Family and domain databases

CDDicd00202, ZnF_GATA, 1 hit
Gene3Di2.30.30.490, 1 hit
InterProiView protein in InterPro
IPR002951, Atrophin-like
IPR001025, BAH_dom
IPR043151, BAH_sf
IPR000949, ELM2_dom
IPR009057, Homeobox-like_sf
IPR001005, SANT/Myb
IPR017884, SANT_dom
IPR000679, Znf_GATA
PfamiView protein in Pfam
PF03154, Atrophin-1, 1 hit
PF01426, BAH, 1 hit
PF01448, ELM2, 1 hit
PF00320, GATA, 1 hit
SMARTiView protein in SMART
SM00439, BAH, 1 hit
SM01189, ELM2, 1 hit
SM00717, SANT, 1 hit
SM00401, ZnF_GATA, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51038, BAH, 1 hit
PS51156, ELM2, 1 hit
PS51293, SANT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0Z0G7_TAEGU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0Z0G7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: June 17, 2020
Last modified: August 12, 2020
This is version 52 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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