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Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Taeniopygia guttata (Zebra finch) (Poephila guttata)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi593 – 668Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-TGU-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR)
R-TGU-383280 Nuclear Receptor transcription pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiTaeniopygia guttata (Zebra finch) (Poephila guttata)Imported
Taxonomic identifieri59729 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePasseriformesPasseroideaEstrildidaeEstrildinaeTaeniopygia
Proteomesi
  • UP000007754 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi59729.ENSTGUP00000002663

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini593 – 668Nuclear receptorInterPro annotationAdd BLAST76
Domaini718 – 952NR LBDInterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
InParanoidiH0YWJ0
OMAiSKICLVC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

H0YWJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKGYHSYP EGLDMERRWG QVSQSVEYSS IGAGEQTDDS NYMEIVNVSC
60 70 80 90 100
AAGTFTNSSA QGNSKEKPEL LSCLQQDTAS CLLRSDITET ESKELVRQRW
110 120 130 140 150
PESMELAGSH FRHYSGSPGK IYQNVEQLVK LYKENGHCSS PLHSSSRPLR
160 170 180 190 200
SLMSDSGSTV NGGAMHTIVK SPIMCQEKSP SGCSPQNMAS SVCSPAGVNS
210 220 230 240 250
MSSTTASFGN FSMHSPMGQG TPLSRSPNVE NRGSMLHSPA HISNVGSPLS
260 270 280 290 300
SPISSMKSPI SSPPSHCSVK SPVSSPNNIT MRSSVSSPAN LNSKSSIASP
310 320 330 340 350
SNANNRSTRS SPAVSTVGSS ICSPVNNSIG FLPSGTPVGP SRSQDTVPSP
360 370 380 390 400
ETKDKGAQEL TFPKMEEMEN AISNNSQMNL VQFIKPEPDG SFGGACIGDS
410 420 430 440 450
SSKMNSDSPF SVPVKQESAK HPCSGASFKG NQTVNPFPFT DGSYFSFMDD
460 470 480 490 500
KDYYSLSGIL GPPVSSFDGN CEGSGFPNPG LRVGIKQEPD DGSYYQENNI
510 520 530 540 550
PSSAIVGVNS GGQSFHYRIG AQGTISLSRP VAREQTFQHL SSFPAVSTLV
560 570 580 590 600
ETWKSHSELA SRRSDGYPVL EYIPENVSSS SLRSVSTGSS RPSKVCLVCG
610 620 630 640 650
DEASGCHYGV VTCGSCKVFF KRAVEGQHNY LCAGRNDCII DKIRRKNCPA
660 670 680 690 700
CRLQKCLQAG MNLGARKSKK LGKLKGIHEE PQQRQQPPPQ SPEEGTTYIA
710 720 730 740 750
PVTEPSVNTA LVPHMSAISP ALTPSPVKIL ESIEPEIVYA GYDSSKPDTA
760 770 780 790 800
EYLLSTLNRL AGKQMIQVVK WAKILPGFRN LPLEDQITLI QYSWMCLSSF
810 820 830 840 850
ALSWRSYKHT NSQFLYFAPD LIFDEERMRQ SAMFELCQGM HQISLQFVRL
860 870 880 890 900
QLSFEEYTIM KVLLLLSTVP KDGLKSQAAF EEMRANYIKE LKKMVTKCPS
910 920 930 940 950
NSGQSWQRFY QLTKLLDSMH DLVSDLLEFC FYTFRESQAL KVEFPAMLVE
960 970
IISDQLPKVE SGNAKPLYFH RK
Length:972
Mass (Da):106,108
Last modified:February 22, 2012 - v1
Checksum:iE9241BE2D5A99B8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABQF01041332 Genomic DNA No translation available.
ABQF01041333 Genomic DNA No translation available.
ABQF01041334 Genomic DNA No translation available.
ABQF01041335 Genomic DNA No translation available.
ABQF01041336 Genomic DNA No translation available.
ABQF01041337 Genomic DNA No translation available.
ABQF01041338 Genomic DNA No translation available.
ABQF01041339 Genomic DNA No translation available.
ABQF01041340 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSTGUT00000002691; ENSTGUP00000002663; ENSTGUG00000002577

Similar proteinsi

Entry informationi

Entry nameiH0YWJ0_TAEGU
AccessioniPrimary (citable) accession number: H0YWJ0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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