UniProtKB - H0YNL5 (H0YNL5_HUMAN)
Protein
Submitted name:
Ubiquitin carboxyl-terminal hydrolase 8
Gene
USP8
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Ubiquitin carboxyl-terminal hydrolase 8Imported |
Gene namesi | Name:USP8Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:12631, USP8 |
VEuPathDBi | HostDB:ENSG00000138592.13 |
Expressioni
Gene expression databases
Bgeei | ENSG00000138592, Expressed in sural nerve and 235 other tissues |
ExpressionAtlasi | H0YNL5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 115 | USP8_dimerInterPro annotationAdd BLAST | 108 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 99 – 133 | Sequence analysisAdd BLAST | 35 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000157542 |
Family and domain databases
InterProi | View protein in InterPro IPR015063, USP8_dimer |
Pfami | View protein in Pfam PF08969, USP8_dimer, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
H0YNL5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAVASVPKE LYLSSSLKDL NKKTEVKPEK ISTKSYVHSA LKIFKTAEEC
60 70 80 90 100
RLDRDEERAY VLYMKYVTVY NLIKKRPDFK QQQDYFHSIL GPGNIKKAVE
110 120 130
EAERLSESLK LRYEEAEVRK KLEEKDRQEE AQRLQ
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP40818 | UBP8_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 KIAA0055, UBPY | 1,118 | Annotation score: | ||
A0A075B720 | A0A075B720_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 | 480 | Annotation score: | ||
H0YM17 | H0YM17_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 | 73 | Annotation score: | ||
H0YM47 | H0YM47_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 | 125 | Annotation score: | ||
H0YKV1 | H0YKV1_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 | 136 | Annotation score: | ||
H0YLH2 | H0YLH2_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 | 96 | Annotation score: | ||
H0YLS3 | H0YLS3_HUMAN | Ubiquitin carboxyl-terminal hydrola... | USP8 | 62 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 135 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012170 Genomic DNA No translation available. KF459553 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000558091; ENSP00000454059; ENSG00000138592 |
UCSCi | uc059jdp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012170 Genomic DNA No translation available. KF459553 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | H0YNL5 |
PeptideAtlasi | H0YNL5 |
ProteomicsDBi | 40598 |
Protocols and materials databases
Antibodypediai | 1385, 260 antibodies |
Genome annotation databases
Ensembli | ENST00000558091; ENSP00000454059; ENSG00000138592 |
UCSCi | uc059jdp.1, human |
Organism-specific databases
HGNCi | HGNC:12631, USP8 |
OpenTargetsi | ENSG00000138592 |
VEuPathDBi | HostDB:ENSG00000138592.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157542 |
Miscellaneous databases
ChiTaRSi | USP8, human |
Gene expression databases
Bgeei | ENSG00000138592, Expressed in sural nerve and 235 other tissues |
ExpressionAtlasi | H0YNL5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR015063, USP8_dimer |
Pfami | View protein in Pfam PF08969, USP8_dimer, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YNL5_HUMAN | |
Accessioni | H0YNL5Primary (citable) accession number: H0YNL5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | February 10, 2021 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |