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UniProtKB - H0YMU6 (H0YMU6_HUMAN)
Protein
Submitted name:
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
Gene
PCK2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- GTP binding Source: InterPro
- phosphoenolpyruvate carboxykinase activity Source: InterPro
GO - Biological processi
- gluconeogenesis Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Phosphoenolpyruvate carboxykinase [GTP], mitochondrial |
Gene namesi | Name:PCK2 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:8725, PCK2 |
VEuPathDBi | HostDB:ENSG00000100889 |
Expressioni
Gene expression databases
Bgeei | ENSG00000100889, Expressed in duodenum and 192 other tissues |
ExpressionAtlasi | H0YMU6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 107 | PEPCK_NInterPro annotationAdd BLAST | 107 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 85 – 107 | DisorderedSequence analysisAdd BLAST | 23 |
Phylogenomic databases
GeneTreei | ENSGT00390000001912 |
OMAi | PAGKKHY |
Family and domain databases
Gene3Di | 3.40.449.10, 1 hit |
InterProi | View protein in InterPro IPR008209, PEP_carboxykinase_GTP IPR035078, PEP_carboxykinase_GTP_N IPR008210, PEP_carboxykinase_N |
PANTHERi | PTHR11561, PTHR11561, 1 hit |
Pfami | View protein in Pfam PF17297, PEPCK_N, 1 hit |
SUPFAMi | SSF68923, SSF68923, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
H0YMU6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSPADFQRAV DERFPGCMQG RTMYVLPFSM GPVGSPLSRI GVQLTDSAYV
60 70 80 90 100
VASMRIMTRL GTPVLQALGD GDFVKCLHSV GQPLTGQGEP VSQWPCNPEK
TLIGHVP
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ16822 | PCKGM_HUMAN | Phosphoenolpyruvate carboxykinase [... | PCK2 PEPCK2 | 640 | Annotation score: | ||
H0YM31 | H0YM31_HUMAN | Phosphoenolpyruvate carboxykinase (... | PCK2 | 509 | Annotation score: | ||
H0YML5 | H0YML5_HUMAN | Phosphoenolpyruvate carboxykinase (... | PCK2 | 474 | Annotation score: | ||
H0YNG4 | H0YNG4_HUMAN | Phosphoenolpyruvate carboxykinase [... | PCK2 | 113 | Annotation score: | ||
H0YMA5 | H0YMA5_HUMAN | Phosphoenolpyruvate carboxykinase [... | PCK2 | 122 | Annotation score: | ||
H0YMY3 | H0YMY3_HUMAN | Phosphoenolpyruvate carboxykinase [... | PCK2 | 109 | Annotation score: | ||
H0YNH9 | H0YNH9_HUMAN | Phosphoenolpyruvate carboxykinase [... | PCK2 | 42 | Annotation score: | ||
H0YKC4 | H0YKC4_HUMAN | Phosphoenolpyruvate carboxykinase [... | PCK2 | 62 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 107 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL136295 Genomic DNA No translation available. KF455834 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000559837.5; ENSP00000453751.1; ENSG00000100889.12 |
UCSCi | uc058zvg.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL136295 Genomic DNA No translation available. KF455834 Genomic DNA No translation available. |
3D structure databases
SMRi | H0YMU6 |
ModBasei | Search... |
Proteomic databases
MaxQBi | H0YMU6 |
PeptideAtlasi | H0YMU6 |
ProteomicsDBi | 40364 |
Protocols and materials databases
Antibodypediai | 8846, 304 antibodies from 36 providers |
Genome annotation databases
Ensembli | ENST00000559837.5; ENSP00000453751.1; ENSG00000100889.12 |
UCSCi | uc058zvg.1, human |
Organism-specific databases
HGNCi | HGNC:8725, PCK2 |
OpenTargetsi | ENSG00000100889 |
VEuPathDBi | HostDB:ENSG00000100889 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000001912 |
OMAi | PAGKKHY |
Miscellaneous databases
ChiTaRSi | PCK2, human |
Gene expression databases
Bgeei | ENSG00000100889, Expressed in duodenum and 192 other tissues |
ExpressionAtlasi | H0YMU6, baseline and differential |
Family and domain databases
Gene3Di | 3.40.449.10, 1 hit |
InterProi | View protein in InterPro IPR008209, PEP_carboxykinase_GTP IPR035078, PEP_carboxykinase_GTP_N IPR008210, PEP_carboxykinase_N |
PANTHERi | PTHR11561, PTHR11561, 1 hit |
Pfami | View protein in Pfam PF17297, PEPCK_N, 1 hit |
SUPFAMi | SSF68923, SSF68923, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YMU6_HUMAN | |
Accessioni | H0YMU6Primary (citable) accession number: H0YMU6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | May 25, 2022 | |
This is version 59 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |