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Protein
Submitted name:

Eukaryotic translation initiation factor 5

Gene

EIF5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 5Imported
Gene namesi
Name:EIF5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000100664.10
HGNCiHGNC:3299 EIF5

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100664

PTM / Processingi

Proteomic databases

MaxQBiH0YMJ8
PeptideAtlasiH0YMJ8
PRIDEiH0YMJ8

Expressioni

Gene expression databases

BgeeiENSG00000100664 Expressed in 244 organ(s), highest expression level in female gonad
ExpressionAtlasiH0YMJ8 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 101eIF2B_5InterPro annotationAdd BLAST89

Phylogenomic databases

eggNOGiKOG2767 Eukaryota
COG1601 LUCA
GeneTreeiENSGT00390000016478

Family and domain databases

InterProiView protein in InterPro
IPR002735 Transl_init_fac_IF2/IF5
IPR016189 Transl_init_fac_IF2/IF5_N
PfamiView protein in Pfam
PF01873 eIF-5_eIF-2B, 1 hit
SMARTiView protein in SMART
SM00653 eIF2B_5, 1 hit
SUPFAMiSSF100966 SSF100966, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H0YMJ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVNVNRSVS DQFYRYKMPR LIAKVEGKGN GIKTVIVNMV DVAKALNRPP
60 70 80 90 100
TYPTKYFGCE LGAQTQFDVK NDRYIVNGSH EANKLQDMLD GFIKKFVLCP

E
Length:101
Mass (Da):11,461
Last modified:February 22, 2012 - v1
Checksum:i63BAEE88F4D93457
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P55010IF5_HUMAN
Eukaryotic translation initiation f...
EIF5
431Annotation score:
H0YN40H0YN40_HUMAN
Eukaryotic translation initiation f...
EIF5
200Annotation score:
H0YLZ1H0YLZ1_HUMAN
Eukaryotic translation initiation f...
EIF5
146Annotation score:
H0YK11H0YK11_HUMAN
Eukaryotic translation initiation f...
EIF5
68Annotation score:
H0YM54H0YM54_HUMAN
Eukaryotic translation initiation f...
EIF5
109Annotation score:
H0YK29H0YK29_HUMAN
Eukaryotic translation initiation f...
EIF5
51Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei101Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138976 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000560338; ENSP00000453633; ENSG00000100664
UCSCiuc059fpl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138976 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YMJ8
PeptideAtlasiH0YMJ8
PRIDEiH0YMJ8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000560338; ENSP00000453633; ENSG00000100664
UCSCiuc059fpl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000100664.10
HGNCiHGNC:3299 EIF5
OpenTargetsiENSG00000100664
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2767 Eukaryota
COG1601 LUCA
GeneTreeiENSGT00390000016478

Miscellaneous databases

ChiTaRSiEIF5 human

Gene expression databases

BgeeiENSG00000100664 Expressed in 244 organ(s), highest expression level in female gonad
ExpressionAtlasiH0YMJ8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002735 Transl_init_fac_IF2/IF5
IPR016189 Transl_init_fac_IF2/IF5_N
PfamiView protein in Pfam
PF01873 eIF-5_eIF-2B, 1 hit
SMARTiView protein in SMART
SM00653 eIF2B_5, 1 hit
SUPFAMiSSF100966 SSF100966, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YMJ8_HUMAN
AccessioniPrimary (citable) accession number: H0YMJ8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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