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Protein
Submitted name:

COP9 signalosome complex subunit 2

Gene

COPS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
COP9 signalosome complex subunit 2Imported
Gene namesi
Name:COPS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000166200.14
HGNCiHGNC:30747 COPS2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166200

PTM / Processingi

Proteomic databases

EPDiH0YMC2
MaxQBiH0YMC2
PeptideAtlasiH0YMC2
PRIDEiH0YMC2

Expressioni

Gene expression databases

BgeeiENSG00000166200 Expressed in 234 organ(s), highest expression level in cartilage tissue
ExpressionAtlasiH0YMC2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YMC2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 46PCIInterPro annotationAdd BLAST44

Phylogenomic databases

eggNOGiKOG1464 Eukaryota
COG5159 LUCA
GeneTreeiENSGT00530000063301

Family and domain databases

InterProiView protein in InterPro
IPR037750 COPS2
IPR000717 PCI_dom
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10678:SF3 PTHR10678:SF3, 1 hit
PfamiView protein in Pfam
PF01399 PCI, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0YMC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
KTNHSNIMDD PFIREHIEEL LRNIRTQVLI KLIKPYTRIH IPFISKMESR

SCCLG
Length:55
Mass (Da):6,550
Last modified:February 22, 2012 - v1
Checksum:iFF2C30E777D2C2AE
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P61201CSN2_HUMAN
COP9 signalosome complex subunit 2
COPS2 CSN2, TRIP15
443Annotation score:
B4DIH5B4DIH5_HUMAN
cDNA FLJ52928, highly similar to CO...
COPS2
379Annotation score:
H0YM03H0YM03_HUMAN
COP9 signalosome complex subunit 2
COPS2
183Annotation score:
H0YKU5H0YKU5_HUMAN
COP9 signalosome complex subunit 2
COPS2
263Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013452 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000560240; ENSP00000453546; ENSG00000166200
UCSCiuc059izx.1 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013452 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YMC2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0YMC2
MaxQBiH0YMC2
PeptideAtlasiH0YMC2
PRIDEiH0YMC2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000560240; ENSP00000453546; ENSG00000166200
UCSCiuc059izx.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000166200.14
HGNCiHGNC:30747 COPS2
OpenTargetsiENSG00000166200
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1464 Eukaryota
COG5159 LUCA
GeneTreeiENSGT00530000063301

Miscellaneous databases

ChiTaRSiCOPS2 human

Gene expression databases

BgeeiENSG00000166200 Expressed in 234 organ(s), highest expression level in cartilage tissue
ExpressionAtlasiH0YMC2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR037750 COPS2
IPR000717 PCI_dom
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10678:SF3 PTHR10678:SF3, 1 hit
PfamiView protein in Pfam
PF01399 PCI, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YMC2_HUMAN
AccessioniPrimary (citable) accession number: H0YMC2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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