UniProtKB - H0YMC2 (H0YMC2_HUMAN)

BLAST

>tr|H0YMC2|H0YMC2_HUMAN COP9 signalosome complex subunit 2 (Fragment) OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1
KTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKMESRSCCLG

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History
Entry version 41 (12 Sep 2018)
Sequence version 1 (22 Feb 2012)
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Protein

Submitted name:

COP9 signalosome complex subunit 2

Gene

COPS2

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: COP9 signalosome complex subunit 2Imported
Gene namesⁱ	Name:COPS2Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 15

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000166200.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:30747 COPS2

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000166200

OpenTargetsⁱ

ENSG00000166200

PTM / Processingⁱ

Proteomic databases

EPDⁱ	H0YMC2
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	H0YMC2
PeptideAtlas More...PeptideAtlasⁱ	H0YMC2
PRIDEⁱ	H0YMC2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000166200 Expressed in 234 organ(s), highest expression level in cartilage tissue
ExpressionAtlasⁱ	H0YMC2 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	H0YMC2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	3 – 46	PCIInterPro annotationAdd BLAST		44

Phylogenomic databases

eggNOGⁱ	KOG1464 Eukaryota COG5159 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063301

Family and domain databases

InterProⁱ	View protein in InterPro IPR037750 COPS2 IPR000717 PCI_dom IPR036390 WH_DNA-bd_sf
PANTHERⁱ	PTHR10678:SF3 PTHR10678:SF3, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01399 PCI, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show all Align All

H0YMC2-1 [UniParc]FASTA Add to basket

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KTNHSNIMDD PFIREHIEEL LRNIRTQVLI KLIKPYTRIH IPFISKMESR 

SCCLG

Length:55

Mass (Da):6,550

Last modified:February 22, 2012 - v1

Checksum:ⁱFF2C30E777D2C2AE

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

P61201	CSN2_HUMAN	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 2, SGN2, Signalosome subunit 2 (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15, TR-interacting protein 15, TRIP-15)	COPS2 CSN2, TRIP15	443	Annotation score:
B4DIH5	B4DIH5_HUMAN	cDNA FLJ52928, highly similar to CO... cDNA FLJ52928, highly similar to COP9 signalosome complex subunit 2	COPS2	379	Annotation score:
H0YM03	H0YM03_HUMAN	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 2	COPS2	183	Annotation score:
H0YKU5	H0YKU5_HUMAN	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 2	COPS2	263	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC013452 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC013452 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000560240; ENSP00000453546; ENSG00000166200
UCSC genome browser More...UCSCⁱ	uc059izx.1 human

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC013452 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC013452 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	H0YMC2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	H0YMC2
MaxQBⁱ	H0YMC2
PeptideAtlasⁱ	H0YMC2
PRIDEⁱ	H0YMC2

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000560240; ENSP00000453546; ENSG00000166200
UCSCⁱ	uc059izx.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000166200.14
HGNCⁱ	HGNC:30747 COPS2
OpenTargetsⁱ	ENSG00000166200
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1464 Eukaryota COG5159 LUCA
GeneTreeⁱ	ENSGT00530000063301

Miscellaneous databases

ChiTaRSⁱ	COPS2 human

ChiTaRSⁱ

COPS2 human

Gene expression databases

Bgeeⁱ	ENSG00000166200 Expressed in 234 organ(s), highest expression level in cartilage tissue
ExpressionAtlasⁱ	H0YMC2 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR037750 COPS2 IPR000717 PCI_dom IPR036390 WH_DNA-bd_sf
PANTHERⁱ	PTHR10678:SF3 PTHR10678:SF3, 1 hit
Pfamⁱ	View protein in Pfam PF01399 PCI, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H0YMC2_HUMAN
Accessionⁱ	H0YMC2Primary (citable) accession number: H0YMC2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 22, 2012
	Last sequence update:	February 22, 2012
	Last modified:	September 12, 2018
	This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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UniParc

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Supporting data

UniProtKB - H0YMC2 (H0YMC2_HUMAN)

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COP9 signalosome complex subunit 2

COPS2

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ