UniProtKB - H0YL12 (H0YL12_HUMAN)

BLAST

>tr|H0YL12|H0YL12_HUMAN Electron transfer flavoprotein subunit alpha, mitochondrial (Fragment) OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=8
XAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPR
VAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGS
ASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGVETEVLHVGQAGLEILTSGDP
PTSASQSVGITGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKI

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History
Entry version 41 (12 Sep 2018)
Sequence version 8 (05 Oct 2016)
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Protein

Submitted name:

Electron transfer flavoprotein subunit alpha, mitochondrial

Gene

ETFA

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Electron transfer flavoprotein subunit alpha, mitochondrialImported
Gene namesⁱ	Name:ETFAImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 15

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000140374.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:3481 ETFA

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000140374

OpenTargetsⁱ

ENSG00000140374

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	H0YL12
PRIDEⁱ	H0YL12

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000140374 Expressed in 232 organ(s), highest expression level in oocyte
ExpressionAtlasⁱ	H0YL12 baseline and differential

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 141	ETFInterPro annotationAdd BLAST		141

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000013422

GeneTreeⁱ

ENSGT00390000013422

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01715 ETF_alpha, 1 hit
Gene3Dⁱ	3.40.50.620, 1 hit
InterProⁱ	View protein in InterPro IPR029035 DHS-like_NAD/FAD-binding_dom IPR014730 ETF_a/b_N IPR033947 ETF_alpha_N IPR014731 ETF_asu_C IPR014729 Rossmann-like_a/b/a_fold
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01012 ETF, 1 hit PF00766 ETF_alpha, 1 hit
SMARTⁱ	View protein in SMART SM00893 ETF, 1 hit
SUPFAMⁱ	SSF52467 SSF52467, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show all Align All

H0YL12-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
XAQDLCKVAG IAKVLVAQHD VYKGLLPEEL TPLILATQKQ FNYTHICAGA 
        60         70         80         90        100
SAFGKNLLPR VAAKLEVAPI SDIIAIKSPD TFVRTIYAGN ALCTVKCDEK 
       110        120        130        140        150
VKVFSVRGTS FDAAATSGGS ASSEKASSTS PVEISEWLDQ KLTKSDRPEL 
       160        170        180        190        200
TGAKVVVSGV ETEVLHVGQA GLEILTSGDP PTSASQSVGI TGRGLKSGEN 
       210        220        230 
FKLLYDLADQ LHAAVGASRA AVDAGFVPND MQVGQTGKI

Length:239

Mass (Da):24,909

Last modified:October 5, 2016 - v8

Checksum:ⁱ21D6437850D647C7

Computationally mapped potential isoform sequencesⁱ

There are 10 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

P13804	ETFA_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF	ETFA	333	Annotation score:
H0YNX6	H0YNX6_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	254	Annotation score:
H0YLU7	H0YLU7_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	303	Annotation score:
H0YK49	H0YK49_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	229	Annotation score:
H0YL83	H0YL83_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	73	Annotation score:
H0YKF0	H0YKF0_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	289	Annotation score:
J3KN60	J3KN60_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	64	Annotation score:
H3BV91	H3BV91_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	46	Annotation score:
H0YM12	H0YM12_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial	ETFA	39	Annotation score:
H0YMU8	H0YMU8_HUMAN	Electron transfer flavoprotein subu... Electron transfer flavoprotein subunit alpha, mitochondrial (Electron-transfer-flavoprotein alpha polypeptide isoform 2)	ETFA	45	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1
Non-terminal residueⁱ	239	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC027243 Genomic DNA No translation available. AC091100 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC027243 Genomic DNA No translation available.
AC091100 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000560345; ENSP00000453017; ENSG00000140374
UCSC genome browser More...UCSCⁱ	uc059lwn.1 human

Protein	Similar proteins		Species	Score	Length	Source
H0YL12	ETFA isoform 13 (Fragment)		PONAB		239	UniRef90_H0YL12
ETFA isoform 17 (Fragment)		PANTR		239

Protein	Similar proteins		Species	Score	Length	Source
H0YL12	Electron-transfer-flavoprotein, alpha polypeptide		LATCH		232	UniRef50_H3ARB5
Uncharacterized protein (Fragment)		HALAL		256
Uncharacterized protein		TAEGU		211
Electron transfer flavoprotein subunit alpha		PROCO		207
Uncharacterized protein (Fragment)		ANTCR		178
+10

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC027243 Genomic DNA No translation available. AC091100 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC027243 Genomic DNA No translation available.
AC091100 Genomic DNA No translation available.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	H0YL12
PRIDEⁱ	H0YL12

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000560345; ENSP00000453017; ENSG00000140374
UCSCⁱ	uc059lwn.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000140374.15
HGNCⁱ	HGNC:3481 ETFA
OpenTargetsⁱ	ENSG00000140374
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

GeneTreeⁱ	ENSGT00390000013422

GeneTreeⁱ

ENSGT00390000013422

Miscellaneous databases

ChiTaRSⁱ	ETFA human

ChiTaRSⁱ

ETFA human

Gene expression databases

Bgeeⁱ	ENSG00000140374 Expressed in 232 organ(s), highest expression level in oocyte
ExpressionAtlasⁱ	H0YL12 baseline and differential

Family and domain databases

CDDⁱ	cd01715 ETF_alpha, 1 hit
Gene3Dⁱ	3.40.50.620, 1 hit
InterProⁱ	View protein in InterPro IPR029035 DHS-like_NAD/FAD-binding_dom IPR014730 ETF_a/b_N IPR033947 ETF_alpha_N IPR014731 ETF_asu_C IPR014729 Rossmann-like_a/b/a_fold
Pfamⁱ	View protein in Pfam PF01012 ETF, 1 hit PF00766 ETF_alpha, 1 hit
SMARTⁱ	View protein in SMART SM00893 ETF, 1 hit
SUPFAMⁱ	SSF52467 SSF52467, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H0YL12_HUMAN
Accessionⁱ	H0YL12Primary (citable) accession number: H0YL12
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 22, 2012
	Last sequence update:	October 5, 2016
	Last modified:	September 12, 2018
	This is version 41 of the entry and version 8 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - H0YL12 (H0YL12_HUMAN)

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Electron transfer flavoprotein subunit alpha, mitochondrial

ETFA

Select a section on the left to see content.

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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UniRef

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Supporting data

UniProtKB - H0YL12 (H0YL12_HUMAN)

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Electron transfer flavoprotein subunit alpha, mitochondrial

ETFA

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ