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Protein
Submitted name:

Aminopeptidase N

Gene

ANPEP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Aminopeptidase NImported
Gene namesi
Name:ANPEPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000166825.13
HGNCiHGNC:500 ANPEP

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 33HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166825

PTM / Processingi

Proteomic databases

MaxQBiH0YKT6
PeptideAtlasiH0YKT6
PRIDEiH0YKT6

Expressioni

Gene expression databases

BgeeiENSG00000166825 Expressed in 177 organ(s), highest expression level in jejunal mucosa
ExpressionAtlasiH0YKT6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YKT6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1046 Eukaryota
COG0308 LUCA
GeneTreeiENSGT00760000119082

Family and domain databases

InterProiView protein in InterPro
IPR001930 Peptidase_M1
PANTHERiPTHR11533 PTHR11533, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0YKT6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKGFYISKS LGILGILLGV AAVCTIIALS VVYSQEKNKN ANSSPVASTT
60 70 80 90 100
PSASATTNPA SATTLDQSKA WNRYRLPNTL KPDSYRVTLR PYLTPNDRGL

YVF
Length:103
Mass (Da):11,099
Last modified:February 22, 2012 - v1
Checksum:i2E022D84AC74E512
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P15144AMPN_HUMAN
Aminopeptidase N
ANPEP APN, CD13, PEPN
967Annotation score:
H0YM04H0YM04_HUMAN
Aminopeptidase N
ANPEP
61Annotation score:
H0YMC1H0YMC1_HUMAN
Aminopeptidase N
ANPEP
122Annotation score:
H0YLZ8H0YLZ8_HUMAN
Aminopeptidase N
ANPEP
65Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei103Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018988 Genomic DNA No translation available.
AC079075 Genomic DNA No translation available.
KF510413 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000559874; ENSP00000452934; ENSG00000166825
UCSCiuc059ncd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018988 Genomic DNA No translation available.
AC079075 Genomic DNA No translation available.
KF510413 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YKT6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YKT6
PeptideAtlasiH0YKT6
PRIDEiH0YKT6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000559874; ENSP00000452934; ENSG00000166825
UCSCiuc059ncd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000166825.13
HGNCiHGNC:500 ANPEP
OpenTargetsiENSG00000166825
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1046 Eukaryota
COG0308 LUCA
GeneTreeiENSGT00760000119082

Miscellaneous databases

ChiTaRSiANPEP human

Gene expression databases

BgeeiENSG00000166825 Expressed in 177 organ(s), highest expression level in jejunal mucosa
ExpressionAtlasiH0YKT6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001930 Peptidase_M1
PANTHERiPTHR11533 PTHR11533, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YKT6_HUMAN
AccessioniPrimary (citable) accession number: H0YKT6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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