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Protein
Submitted name:

Transducin-like enhancer protein 3

Gene

TLE3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transducin-like enhancer protein 3Imported
Gene namesi
Name:TLE3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000140332.15
HGNCiHGNC:11839 TLE3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140332

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YKH5
PRIDEiH0YKH5

Expressioni

Gene expression databases

BgeeiENSG00000140332 Expressed in 203 organ(s), highest expression level in blood
ExpressionAtlasiH0YKH5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YKH5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 131TLE_NInterPro annotationAdd BLAST71

Phylogenomic databases

eggNOGiKOG0639 Eukaryota
ENOG410XPX3 LUCA
GeneTreeiENSGT00550000074465

Family and domain databases

InterProiView protein in InterPro
IPR005617 Groucho/TLE_N
IPR009146 Groucho_enhance
PANTHERiPTHR10814 PTHR10814, 1 hit
PfamiView protein in Pfam
PF03920 TLE_N, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

H0YKH5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRPRAWGAVG APTPAGGAAW IWGDERQVPT TAQPQGGPER GHNLVLPSPS
60 70 80 90 100
PASIAGATWR RYYEMSYGLN IEMHKQTEIA KRLNTILAQI MPFLSQEHQQ
110 120 130 140 150
QVAQAVERAK QVTMTELNAI IGQQQLQAQH LSHATHGPPV QLPPHPSGLQ

PPGI
Length:154
Mass (Da):16,766
Last modified:February 22, 2012 - v1
Checksum:i45FD1CE3664AE6DD
GO

Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q04726TLE3_HUMAN
Transducin-like enhancer protein 3
TLE3 KIAA1547
772Annotation score:
H0YL70H0YL70_HUMAN
Transducin-like enhancer protein 3
TLE3
782Annotation score:
H0YKT5H0YKT5_HUMAN
Transducin-like enhancer protein 3
TLE3
774Annotation score:
H0YKN8H0YKN8_HUMAN
Transducin-like enhancer protein 3
TLE3
778Annotation score:
A0A0D9SES8A0A0D9SES8_HUMAN
Transducin-like enhancer protein 3
TLE3
772Annotation score:
F5H7D6F5H7D6_HUMAN
Transducin-like enhancer protein 3
TLE3
699Annotation score:
H0YNT2H0YNT2_HUMAN
Transducin-like enhancer protein 3
TLE3
716Annotation score:
H0YNI7H0YNI7_HUMAN
Transducin-like enhancer protein 3
TLE3
353Annotation score:
H0YLI3H0YLI3_HUMAN
Transducin-like enhancer protein 3
TLE3
611Annotation score:
H0YKH0H0YKH0_HUMAN
Transducin-like enhancer protein 3
TLE3
445Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei154Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026583 Genomic DNA No translation available.
AC068327 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000557984; ENSP00000452809; ENSG00000140332
UCSCiuc059kvf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026583 Genomic DNA No translation available.
AC068327 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YKH5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0YKH5
PRIDEiH0YKH5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000557984; ENSP00000452809; ENSG00000140332
UCSCiuc059kvf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000140332.15
HGNCiHGNC:11839 TLE3
OpenTargetsiENSG00000140332
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0639 Eukaryota
ENOG410XPX3 LUCA
GeneTreeiENSGT00550000074465

Miscellaneous databases

ChiTaRSiTLE3 human

Gene expression databases

BgeeiENSG00000140332 Expressed in 203 organ(s), highest expression level in blood
ExpressionAtlasiH0YKH5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR005617 Groucho/TLE_N
IPR009146 Groucho_enhance
PANTHERiPTHR10814 PTHR10814, 1 hit
PfamiView protein in Pfam
PF03920 TLE_N, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YKH5_HUMAN
AccessioniPrimary (citable) accession number: H0YKH5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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