UniProtKB - H0YJE6 (H0YJE6_HUMAN)
Protein
Submitted name:
Spectrin beta chain, erythrocytic
Gene
SPTB
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Spectrin beta chain, erythrocyticImported |
Gene namesi | Name:SPTBImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:11274, SPTB |
VEuPathDBi | HostDB:ENSG00000070182.17 |
PTM / Processingi
Proteomic databases
MaxQBi | H0YJE6 |
PeptideAtlasi | H0YJE6 |
PRIDEi | H0YJE6 |
ProteomicsDBi | 39307 |
Expressioni
Gene expression databases
Bgeei | ENSG00000070182, Expressed in gastrocnemius and 177 other tissues |
ExpressionAtlasi | H0YJE6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 885 – 988 | PHInterPro annotationAdd BLAST | 104 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 739 – 890 | DisorderedSequence analysisAdd BLAST | 152 | |
Regioni | 1001 – 1028 | DisorderedSequence analysisAdd BLAST | 28 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 79 – 99 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 203 – 230 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 642 – 666 | Sequence analysisAdd BLAST | 25 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 739 – 756 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 850 – 873 | PolyampholyteSequence analysisAdd BLAST | 24 | |
Compositional biasi | 874 – 889 | AcidicSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000158908 |
HOGENOMi | CLU_007259_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR041681, PH_9 IPR001849, PH_domain IPR018159, Spectrin/alpha-actinin IPR002017, Spectrin_repeat |
Pfami | View protein in Pfam PF15410, PH_9, 1 hit PF00435, Spectrin, 7 hits |
SMARTi | View protein in SMART SM00233, PH, 1 hit SM00150, SPEC, 7 hits |
PROSITEi | View protein in PROSITE PS50003, PH_DOMAIN, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
H0YJE6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GKQLMDEKPQ FTALVSQKLE ALHRLWDELQ ATTKEKTQHL SAARSSDLRL
60 70 80 90 100
QTHADLNKWI SAMEDQLRSD DPGKDLTSVN RMLAKLKRVE DQVNVRKEEL
110 120 130 140 150
GELFAQVPSM GEEGGDADLS IEKRFLDLLE PLGRRKKQLE SSRAKLQISR
160 170 180 190 200
DLEDETLWVE ERLPLAQSAD YGTNLQTVQL FMKKNQTLQN EILGHTPRVE
210 220 230 240 250
DVLQRGQQLV EAAEIDCQDL EERLGHLQSS WDRLREAAAG RLQRLRDANE
260 270 280 290 300
AQQYYLDADE AEAWIGEQEL YVISDEIPKD EEGAIVMLKR HLRQQRAVED
310 320 330 340 350
YGRNIKQLAS RAQGLLSAGH PEGEQIIRLQ GQVDKHYAGL KDVAEERKRK
360 370 380 390 400
LENMYHLFQL KRETDDLEQW ISEKELVASS PEMGQDFDHV TLLRDKFRDF
410 420 430 440 450
ARETGAIGQE RVDNVNAFIE RLIDAGHSEA ATIAEWKDGL NEMWADLLEL
460 470 480 490 500
IDTRMQLLAA SYDLHRYFYT GAEILGLIDE KHRELPEDVG LDASTAESFH
510 520 530 540 550
RVHTAFEREL HLLGVQVQQF QDVATRLQTA YAGEKAEAIQ NKEQEVSAAW
560 570 580 590 600
QALLDACAGR RTQLVDTADK FRFFSMARDL LSWMESIIRQ IETQERPRDV
610 620 630 640 650
SSVELLMKYH QGINAEIETR SKNFSACLEL GESLLQRQHQ ASEEIREKLQ
660 670 680 690 700
QVMSRRKEMN EKWEARWERL RMLLEVCQFS RDASVAEAWL IAQEPYLASG
710 720 730 740 750
DFGHTVDSVE KLIKRHEAFE KSTASWAERF AALEKPTTLE LKERQIAERP
760 770 780 790 800
AEETGPQEEE GETAGEAPVS HHAATERTSP GEEEGTWPQN LQQPPPPGQH
810 820 830 840 850
KDGQKSTGDE RPTTEPLFKV LDTPLSEGDE PATLPAPRDH GQSVQMEGYL
860 870 880 890 900
GRKHDLEGPN KKASNSKGEE GEERRETEEE DEEEEETESV AVEMQQHASH
910 920 930 940 950
VSWNNLYCVL RNSELTFYKD AKNLALGMPY HGEEPLALRH AICEIAANYK
960 970 980 990 1000
KKKHVFKLRL SNGSEWLFHG KDEEEMLSWL QGVSTAINES QSIRVKAQSL
1010 1020
PLPSLSGPDA SLGKKDKEKR FSFFPKKK
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP11277 | SPTB1_HUMAN | Spectrin beta chain, erythrocytic | SPTB SPTB1 | 2,137 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL121774 Genomic DNA No translation available. AL135745 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000553938; ENSP00000451324; ENSG00000070182 |
UCSCi | uc059cko.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL121774 Genomic DNA No translation available. AL135745 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | H0YJE6 |
PeptideAtlasi | H0YJE6 |
PRIDEi | H0YJE6 |
ProteomicsDBi | 39307 |
Protocols and materials databases
Antibodypediai | 183, 109 antibodies |
Genome annotation databases
Ensembli | ENST00000553938; ENSP00000451324; ENSG00000070182 |
UCSCi | uc059cko.1, human |
Organism-specific databases
HGNCi | HGNC:11274, SPTB |
OpenTargetsi | ENSG00000070182 |
VEuPathDBi | HostDB:ENSG00000070182.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158908 |
HOGENOMi | CLU_007259_0_0_1 |
Miscellaneous databases
ChiTaRSi | SPTB, human |
Gene expression databases
Bgeei | ENSG00000070182, Expressed in gastrocnemius and 177 other tissues |
ExpressionAtlasi | H0YJE6, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR041681, PH_9 IPR001849, PH_domain IPR018159, Spectrin/alpha-actinin IPR002017, Spectrin_repeat |
Pfami | View protein in Pfam PF15410, PH_9, 1 hit PF00435, Spectrin, 7 hits |
SMARTi | View protein in SMART SM00233, PH, 1 hit SM00150, SPEC, 7 hits |
PROSITEi | View protein in PROSITE PS50003, PH_DOMAIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YJE6_HUMAN | |
Accessioni | H0YJE6Primary (citable) accession number: H0YJE6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | February 10, 2021 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |