UniProtKB - H0YJ78 (H0YJ78_HUMAN)
Protein
Submitted name:
Lysosomal cobalamin transporter ABCD4
Gene
ABCD4
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Lysosomal cobalamin transporter ABCD4Imported |
Gene namesi | Name:ABCD4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:68, ABCD4 |
VEuPathDBi | HostDB:ENSG00000119688.20 |
Expressioni
Gene expression databases
Bgeei | ENSG00000119688, Expressed in left lobe of thyroid gland and 218 other tissues |
ExpressionAtlasi | H0YJ78, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 17 – 126 | ABC transporterInterPro annotationAdd BLAST | 110 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 116 – 135 | DisorderedSequence analysisAdd BLAST | 20 |
Phylogenomic databases
GeneTreei | ENSGT00950000182955 |
HOGENOMi | CLU_1478295_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR003439, ABC_transporter-like IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
H0YJ78-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XERVSISAPS SDKPLIKDLS LKISEGQSLL ITGNTGTGKT SLLRVLGGLW
60 70 80 90 100
TSTRGSVQML TDFGPHGVLF LPQKPFFTDG TLREQVIYPL KEVYPDSGSA
110 120 130 140 150
DDERILRFLE LAGLVSGERD PQDPSPPGST SYSPTWWQGQ RAWTSRWTGT
160 170 180
GMMFCPRGRC NGSPLPDSST CSRSTQCLMK PPVP
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO14678 | ABCD4_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 PXMP1L | 606 | Annotation score: | ||
H0YJX8 | H0YJX8_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 94 | Annotation score: | ||
G3V4U7 | G3V4U7_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 203 | Annotation score: | ||
H0YJL8 | H0YJL8_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 205 | Annotation score: | ||
H0YCY9 | H0YCY9_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 173 | Annotation score: | ||
G3V3W1 | G3V3W1_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 98 | Annotation score: | ||
H0YJ82 | H0YJ82_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 158 | Annotation score: | ||
E9PI46 | E9PI46_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 56 | Annotation score: | ||
E9PPB6 | E9PPB6_HUMAN | Lysosomal cobalamin transporter ABC... | ABCD4 | 39 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005519 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000481348; ENSP00000434792; ENSG00000119688 ENST00000556517; ENSP00000450960; ENSG00000119688 |
UCSCi | uc059dhe.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005519 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PRIDEi | H0YJ78 |
ProteomicsDBi | 39241 |
Protocols and materials databases
Antibodypediai | 184, 226 antibodies |
Genome annotation databases
Ensembli | ENST00000481348; ENSP00000434792; ENSG00000119688 ENST00000556517; ENSP00000450960; ENSG00000119688 |
UCSCi | uc059dhe.1, human |
Organism-specific databases
HGNCi | HGNC:68, ABCD4 |
OpenTargetsi | ENSG00000119688 |
VEuPathDBi | HostDB:ENSG00000119688.20 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000182955 |
HOGENOMi | CLU_1478295_0_0_1 |
Miscellaneous databases
ChiTaRSi | ABCD4, human |
Gene expression databases
Bgeei | ENSG00000119688, Expressed in left lobe of thyroid gland and 218 other tissues |
ExpressionAtlasi | H0YJ78, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR003439, ABC_transporter-like IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YJ78_HUMAN | |
Accessioni | H0YJ78Primary (citable) accession number: H0YJ78 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | February 10, 2021 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |