UniProtKB - H0YJ78 (H0YJ78_HUMAN)

BLAST

>tr|H0YJ78|H0YJ78_HUMAN ATP-binding cassette sub-family D member 4 (Fragment) OS=Homo sapiens OX=9606 GN=ABCD4 PE=1 SV=1
XERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQML
TDFGPHGVLFLPQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLVSGERD
PQDPSPPGSTSYSPTWWQGQRAWTSRWTGTGMMFCPRGRCNGSPLPDSSTCSRSTQCLMK
PPVP

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History
Entry version 48 (12 Sep 2018)
Sequence version 1 (22 Feb 2012)
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Protein

Submitted name:

ATP-binding cassette sub-family D member 4

Gene

ABCD4

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

ATPase activity Source: InterPro
ATP binding Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ATP-binding cassette sub-family D member 4Imported
Gene namesⁱ	Name:ABCD4Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000119688.20
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:68 ABCD4

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000119688

OpenTargetsⁱ

ENSG00000119688

PTM / Processingⁱ

Proteomic databases

EPDⁱ	H0YJ78
PeptideAtlas More...PeptideAtlasⁱ	H0YJ78
PRIDEⁱ	H0YJ78

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000119688 Expressed in 205 organ(s), highest expression level in left lobe of thyroid gland
ExpressionAtlasⁱ	H0YJ78 baseline and differential

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	17 – 126	ABC transporterInterPro annotationAdd BLAST		110

Phylogenomic databases

eggNOGⁱ	KOG0060 Eukaryota COG4178 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000003950

Family and domain databases

InterProⁱ	View protein in InterPro IPR003439 ABC_transporter-like IPR027417 P-loop_NTPase
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00005 ABC_tran, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show all Align All

H0YJ78-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
XERVSISAPS SDKPLIKDLS LKISEGQSLL ITGNTGTGKT SLLRVLGGLW 
        60         70         80         90        100
TSTRGSVQML TDFGPHGVLF LPQKPFFTDG TLREQVIYPL KEVYPDSGSA 
       110        120        130        140        150
DDERILRFLE LAGLVSGERD PQDPSPPGST SYSPTWWQGQ RAWTSRWTGT 
       160        170        180 
GMMFCPRGRC NGSPLPDSST CSRSTQCLMK PPVP

Length:184

Mass (Da):20,059

Last modified:February 22, 2012 - v1

Checksum:ⁱ16E84F1397649032

Computationally mapped potential isoform sequencesⁱ

There are 9 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

O14678	ABCD4_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4 (PMP70-related protein, P70R) (Peroxisomal membrane protein 1-like, PXMP1-L) (Peroxisomal membrane protein 69, PMP69)	ABCD4 PXMP1L	606	Annotation score:
H0YJL8	H0YJL8_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	205	Annotation score:
G3V4U7	G3V4U7_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	203	Annotation score:
H0YJX8	H0YJX8_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	94	Annotation score:
G3V3W1	G3V3W1_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	98	Annotation score:
E9PI46	E9PI46_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	56	Annotation score:
H0YCY9	H0YCY9_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	173	Annotation score:
H0YJ82	H0YJ82_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	158	Annotation score:
E9PPB6	E9PPB6_HUMAN	ATP-binding cassette sub-family D m... ATP-binding cassette sub-family D member 4	ABCD4	39	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC005519 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC005519 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000481348; ENSP00000434792; ENSG00000119688 ENST00000556517; ENSP00000450960; ENSG00000119688
UCSC genome browser More...UCSCⁱ	uc059dhe.1 human

Protein	Similar proteins		Species	Score	Length	Source
H0YJ78	ABCD4 isoform 25 (Fragment)		PONAB		183	UniRef90_H0YJ78

Protein	Similar proteins		Species	Score	Length	Source
H0YJ78	ABCD4 isoform 25 (Fragment)		PONAB		183	UniRef50_H0YJ78

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC005519 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC005519 Genomic DNA No translation available.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	H0YJ78
PeptideAtlasⁱ	H0YJ78
PRIDEⁱ	H0YJ78

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000481348; ENSP00000434792; ENSG00000119688 ENST00000556517; ENSP00000450960; ENSG00000119688
UCSCⁱ	uc059dhe.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000119688.20
HGNCⁱ	HGNC:68 ABCD4
OpenTargetsⁱ	ENSG00000119688
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0060 Eukaryota COG4178 LUCA
GeneTreeⁱ	ENSGT00390000003950

Miscellaneous databases

ChiTaRSⁱ	ABCD4 human

ChiTaRSⁱ

ABCD4 human

Gene expression databases

Bgeeⁱ	ENSG00000119688 Expressed in 205 organ(s), highest expression level in left lobe of thyroid gland
ExpressionAtlasⁱ	H0YJ78 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR003439 ABC_transporter-like IPR027417 P-loop_NTPase
Pfamⁱ	View protein in Pfam PF00005 ABC_tran, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H0YJ78_HUMAN
Accessionⁱ	H0YJ78Primary (citable) accession number: H0YJ78
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 22, 2012
	Last sequence update:	February 22, 2012
	Last modified:	September 12, 2018
	This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - H0YJ78 (H0YJ78_HUMAN)

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ATP-binding cassette sub-family D member 4

ABCD4

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - H0YJ78 (H0YJ78_HUMAN)

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ATP-binding cassette sub-family D member 4

ABCD4

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ