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Protein
Submitted name:

Forkhead box protein N3

Gene

FOXN3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 51Fork-headPROSITE-ProRule annotationAdd BLAST51

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein N3Imported
Gene namesi
Name:FOXN3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000053254.15
HGNCiHGNC:1928 FOXN3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000053254

PTM / Processingi

Proteomic databases

MaxQBiH0YJ54
PeptideAtlasiH0YJ54
PRIDEiH0YJ54

Expressioni

Gene expression databases

BgeeiENSG00000053254 Expressed in 247 organ(s), highest expression level in paraflocculus
ExpressionAtlasiH0YJ54 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YJ54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 51Fork-headInterPro annotationAdd BLAST51

Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
GeneTreeiENSGT00930000150842

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

H0YJ54-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XANAPTGWKN SVRHNLSLNK CFKKVDKERS QSIGKGSLWC IDPEYRQNLI
60 70 80 90 100
QALKKTPYHP HPHVFNTPPT CPQAYQSTSG PPIWPGSTFF KRNGALLQDP
110 120 130 140 150
DIDAASAMML LNTPPEIQAV PPGVIQNGAR VLSRGLFPGV RPLPITPIGV
160 170 180
TAAMRNGITS CRMRTESEPS CGSPVVSGDP KEDHN
Length:185
Mass (Da):20,128
Last modified:February 22, 2012 - v1
Checksum:i3B66106E83944C9B
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O00409FOXN3_HUMAN
Forkhead box protein N3
FOXN3 C14orf116, CHES1
490Annotation score:
G3V3A7G3V3A7_HUMAN
Forkhead box protein N3
FOXN3
208Annotation score:
H0YJG3H0YJG3_HUMAN
Forkhead box protein N3
FOXN3
76Annotation score:
H0YJ22H0YJ22_HUMAN
Forkhead box protein N3
FOXN3
111Annotation score:
H0YJ94H0YJ94_HUMAN
Forkhead box protein N3
FOXN3
91Annotation score:
G3V4N5G3V4N5_HUMAN
Forkhead box protein N3
FOXN3
54Annotation score:
G3V5C7G3V5C7_HUMAN
Forkhead box protein N3
FOXN3
93Annotation score:
H0YJY0H0YJY0_HUMAN
Forkhead box protein N3
FOXN3
122Annotation score:
H0YJ43H0YJ43_HUMAN
Forkhead box protein N3
FOXN3
79Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei185Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137785 Genomic DNA No translation available.
AL138478 Genomic DNA No translation available.
AL157736 Genomic DNA No translation available.
AL163032 Genomic DNA No translation available.
AL356805 Genomic DNA No translation available.
AL357093 Genomic DNA No translation available.
KF455982 Genomic DNA No translation available.
KF455987 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000553840; ENSP00000450833; ENSG00000053254
UCSCiuc059eed.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137785 Genomic DNA No translation available.
AL138478 Genomic DNA No translation available.
AL157736 Genomic DNA No translation available.
AL163032 Genomic DNA No translation available.
AL356805 Genomic DNA No translation available.
AL357093 Genomic DNA No translation available.
KF455982 Genomic DNA No translation available.
KF455987 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YJ54
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YJ54
PeptideAtlasiH0YJ54
PRIDEiH0YJ54

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000553840; ENSP00000450833; ENSG00000053254
UCSCiuc059eed.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000053254.15
HGNCiHGNC:1928 FOXN3
OpenTargetsiENSG00000053254
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
GeneTreeiENSGT00930000150842

Miscellaneous databases

ChiTaRSiFOXN3 human

Gene expression databases

BgeeiENSG00000053254 Expressed in 247 organ(s), highest expression level in paraflocculus
ExpressionAtlasiH0YJ54 baseline and differential

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YJ54_HUMAN
AccessioniPrimary (citable) accession number: H0YJ54
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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