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Protein
Submitted name:

CCR4-NOT transcription complex subunit 2

Gene

CNOT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CCR4-NOT transcription complex subunit 2Imported
Gene namesi
Name:CNOT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111596.11
HGNCiHGNC:7878 CNOT2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111596

PTM / Processingi

Proteomic databases

MaxQBiH0YI80
PeptideAtlasiH0YI80

Expressioni

Gene expression databases

BgeeiENSG00000111596 Expressed in 241 organ(s), highest expression level in intestine
ExpressionAtlasiH0YI80 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YI80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 93NOT2_3_5InterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG2151 Eukaryota
COG5601 LUCA
GeneTreeiENSGT00390000001285

Family and domain databases

Gene3Di2.30.30.1020, 1 hit
InterProiView protein in InterPro
IPR038635 CCR4-NOT_su2/3/5_N_sf
IPR007282 NOT2/3/5_C
PfamiView protein in Pfam
PF04153 NOT2_3_5, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 22 potential isoforms that are computationally mapped.Show allAlign All

H0YI80-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XHLALGSDLT TLGLNLNSPE NLYPKFASPW ASSPCRPQDI DFHVPSEYLT
60 70 80 90
NIHIRDKLAA IKLGRYGEDL LFYLYYMNGG DVLQLLAAVE LSSIWNMTN
Length:99
Mass (Da):11,125
Last modified:February 22, 2012 - v1
Checksum:iE31B028C5224BF7A
GO

Computationally mapped potential isoform sequencesi

There are 22 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NZN8CNOT2_HUMAN
CCR4-NOT transcription complex subu...
CNOT2 CDC36, NOT2, HSPC131, MSTP046
540Annotation score:
F8VV52F8VV52_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
531Annotation score:
F8VRS8F8VRS8_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
276Annotation score:
F8VP97F8VP97_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
321Annotation score:
F8VQF4F8VQF4_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
144Annotation score:
F8W145F8W145_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
309Annotation score:
F8VUB4F8VUB4_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
520Annotation score:
H0YH84H0YH84_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
186Annotation score:
H0YHT6H0YHT6_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
104Annotation score:
H0YI11H0YI11_HUMAN
CCR4-NOT transcription complex subu...
CNOT2
182Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025569 Genomic DNA No translation available.
AC092881 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000548338; ENSP00000448808; ENSG00000111596
UCSCiuc058qwz.1 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025569 Genomic DNA No translation available.
AC092881 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YI80
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YI80
PeptideAtlasiH0YI80

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000548338; ENSP00000448808; ENSG00000111596
UCSCiuc058qwz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000111596.11
HGNCiHGNC:7878 CNOT2
OpenTargetsiENSG00000111596
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2151 Eukaryota
COG5601 LUCA
GeneTreeiENSGT00390000001285

Miscellaneous databases

ChiTaRSiCNOT2 human

Gene expression databases

BgeeiENSG00000111596 Expressed in 241 organ(s), highest expression level in intestine
ExpressionAtlasiH0YI80 baseline and differential

Family and domain databases

Gene3Di2.30.30.1020, 1 hit
InterProiView protein in InterPro
IPR038635 CCR4-NOT_su2/3/5_N_sf
IPR007282 NOT2/3/5_C
PfamiView protein in Pfam
PF04153 NOT2_3_5, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YI80_HUMAN
AccessioniPrimary (citable) accession number: H0YI80
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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