UniProtKB - H0YHG5 (H0YHG5_HUMAN)
Protein
Asparaginase
Gene
ASPG
Organism
Homo sapiens (Human)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 53 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- asparaginase activity Source: UniProtKB-UniRule
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ASPGImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:20123, ASPG |
VEuPathDBi | HostDB:ENSG00000166183.15 |
Expressioni
Gene expression databases
Bgeei | ENSG00000166183, Expressed in right lobe of liver and 103 other tissues |
ExpressionAtlasi | H0YHG5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 15 – 108 | AsparaginaseInterPro annotationAdd BLAST | 94 |
Phylogenomic databases
GeneTreei | ENSGT00390000001610 |
HOGENOMi | CLU_1997679_0_0_1 |
Family and domain databases
Gene3Di | 3.40.50.1170, 1 hit |
InterProi | View protein in InterPro IPR036152, Asp/glu_Ase-like_sf IPR006034, Asparaginase/glutaminase-like IPR027475, Asparaginase/glutaminase_AS2 IPR027474, L-asparaginase_N IPR037152, L-asparaginase_N_sf |
Pfami | View protein in Pfam PF00710, Asparaginase, 1 hit |
PIRSFi | PIRSF001220, L-ASNase_gatD, 1 hit |
SMARTi | View protein in SMART SM00870, Asparaginase, 1 hit |
SUPFAMi | SSF53774, SSF53774, 1 hit |
PROSITEi | View protein in PROSITE PS00917, ASN_GLN_ASE_2, 1 hit PS51732, ASN_GLN_ASE_3, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
H0YHG5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XPASRNQRIL YTVLECQPLF DSSDMTIAEW VCLAQTIKRH YEQYHGFVVI
60 70 80 90 100
HGTDTMAFAA SMLSFMLENL QKTVILTGAQ VPIHALWSDG RENLLGALLM
110 120
AGQYVIPELL TKDLRGEMTP PSVEER
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ86U10 | LPP60_HUMAN | 60 kDa lysophospholipase | ASPG C14orf76 | 573 | Annotation score: | ||
G3V1Y8 | G3V1Y8_HUMAN | Asparaginase | ASPG hCG_23215 | 555 | Annotation score: | ||
H0YHD3 | H0YHD3_HUMAN | 60 kDa lysophospholipase | ASPG | 140 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 126 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL136001 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000551170; ENSP00000447032; ENSG00000166183 |
UCSCi | uc059fvo.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL136001 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H0YHG5 |
PRIDEi | H0YHG5 |
ProteomicsDBi | 38695 |
Protocols and materials databases
Antibodypediai | 59083, 58 antibodies |
Genome annotation databases
Ensembli | ENST00000551170; ENSP00000447032; ENSG00000166183 |
UCSCi | uc059fvo.1, human |
Organism-specific databases
HGNCi | HGNC:20123, ASPG |
OpenTargetsi | ENSG00000166183 |
VEuPathDBi | HostDB:ENSG00000166183.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000001610 |
HOGENOMi | CLU_1997679_0_0_1 |
Gene expression databases
Bgeei | ENSG00000166183, Expressed in right lobe of liver and 103 other tissues |
ExpressionAtlasi | H0YHG5, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.1170, 1 hit |
InterProi | View protein in InterPro IPR036152, Asp/glu_Ase-like_sf IPR006034, Asparaginase/glutaminase-like IPR027475, Asparaginase/glutaminase_AS2 IPR027474, L-asparaginase_N IPR037152, L-asparaginase_N_sf |
Pfami | View protein in Pfam PF00710, Asparaginase, 1 hit |
PIRSFi | PIRSF001220, L-ASNase_gatD, 1 hit |
SMARTi | View protein in SMART SM00870, Asparaginase, 1 hit |
SUPFAMi | SSF53774, SSF53774, 1 hit |
PROSITEi | View protein in PROSITE PS00917, ASN_GLN_ASE_2, 1 hit PS51732, ASN_GLN_ASE_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YHG5_HUMAN | |
Accessioni | H0YHG5Primary (citable) accession number: H0YHG5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | February 10, 2021 | |
This is version 46 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |