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Protein
Submitted name:

Huntingtin-interacting protein 1-related protein

Gene

HIP1R

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Huntingtin-interacting protein 1-related proteinImported
Gene namesi
Name:HIP1RImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000130787.13
HGNCiHGNC:18415 HIP1R

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000130787

PTM / Processingi

Proteomic databases

EPDiH0YH66
MaxQBiH0YH66
PeptideAtlasiH0YH66
PRIDEiH0YH66

Expressioni

Gene expression databases

BgeeiENSG00000130787 Expressed in 209 organ(s), highest expression level in substantia nigra
ExpressionAtlasiH0YH66 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0YH66
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 141I/LWEQInterPro annotationAdd BLAST141

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili100 – 136Sequence analysisAdd BLAST37

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0980 Eukaryota
ENOG410XRXQ LUCA
GeneTreeiENSGT00550000074542

Family and domain databases

InterProiView protein in InterPro
IPR030555 HIP1R
IPR035964 I/LWEQ_dom_sf
IPR002558 ILWEQ_dom
IPR030224 Sla2_fam
PANTHERiPTHR10407 PTHR10407, 1 hit
PTHR10407:SF10 PTHR10407:SF10, 1 hit
PfamiView protein in Pfam
PF01608 I_LWEQ, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD011820 ILWEQ, 1 hit
SMARTiView protein in SMART
SM00307 ILWEQ, 1 hit
SUPFAMiSSF109885 SSF109885, 1 hit
PROSITEiView protein in PROSITE
PS50945 I_LWEQ, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

H0YH66-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XRHPLACRRR SWRAAGEAAD KVVLHTGKYE ELIVCSHEIA ASTAQLVAAS
60 70 80 90 100
KVKANKHSPH LSRLQECSRT VNERAANVVA STKSGQEQIE DRDTMDFSGL
110 120 130 140 150
SLIKLKKQEM ETQVRVLELE KTLEAERMRL GELRKQHYVL AGASGSPGEE
160 170 180 190
VAIRPSTAPR SVTTKKPPLA QKPSVAPRQD HQLDKKDGIY PAQLVNY
Length:197
Mass (Da):21,850
Last modified:February 22, 2012 - v1
Checksum:i4568D1A6C6597710
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75146HIP1R_HUMAN
Huntingtin-interacting protein 1-re...
HIP1R HIP12, KIAA0655
1,068Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027290 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000535012; ENSP00000446236; ENSG00000130787
UCSCiuc058uot.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027290 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YH66
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0YH66
MaxQBiH0YH66
PeptideAtlasiH0YH66
PRIDEiH0YH66

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535012; ENSP00000446236; ENSG00000130787
UCSCiuc058uot.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000130787.13
HGNCiHGNC:18415 HIP1R
OpenTargetsiENSG00000130787
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0980 Eukaryota
ENOG410XRXQ LUCA
GeneTreeiENSGT00550000074542

Miscellaneous databases

ChiTaRSiHIP1R human

Gene expression databases

BgeeiENSG00000130787 Expressed in 209 organ(s), highest expression level in substantia nigra
ExpressionAtlasiH0YH66 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR030555 HIP1R
IPR035964 I/LWEQ_dom_sf
IPR002558 ILWEQ_dom
IPR030224 Sla2_fam
PANTHERiPTHR10407 PTHR10407, 1 hit
PTHR10407:SF10 PTHR10407:SF10, 1 hit
PfamiView protein in Pfam
PF01608 I_LWEQ, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD011820 ILWEQ, 1 hit
SMARTiView protein in SMART
SM00307 ILWEQ, 1 hit
SUPFAMiSSF109885 SSF109885, 1 hit
PROSITEiView protein in PROSITE
PS50945 I_LWEQ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YH66_HUMAN
AccessioniPrimary (citable) accession number: H0YH66
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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