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Protein
Submitted name:

Multiple PDZ domain protein

Gene

MPDZ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Multiple PDZ domain proteinImported
Gene namesi
Name:MPDZImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000107186.16
HGNCiHGNC:7208 MPDZ

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000107186

PTM / Processingi

Proteomic databases

EPDiH0YGQ3
MaxQBiH0YGQ3
PeptideAtlasiH0YGQ3
PRIDEiH0YGQ3

Expressioni

Gene expression databases

BgeeiENSG00000107186 Expressed in 224 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0YGQ3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YGQ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 82PDZInterPro annotationAdd BLAST69
Domaini157 – 216PDZInterPro annotationAdd BLAST60
Domaini286 – 369PDZInterPro annotationAdd BLAST84
Domaini419 – 500PDZInterPro annotationAdd BLAST82
Domaini565 – 648PDZInterPro annotationAdd BLAST84
Domaini661 – 743PDZInterPro annotationAdd BLAST83
Domaini798 – 884PDZInterPro annotationAdd BLAST87
Domaini923 – 1006PDZInterPro annotationAdd BLAST84

Phylogenomic databases

eggNOGiKOG3528 Eukaryota
ENOG4110362 LUCA
GeneTreeiENSGT00760000119017

Family and domain databases

InterProiView protein in InterPro
IPR032078 MPDZ
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF16667 MPDZ_u10, 1 hit
PF00595 PDZ, 7 hits
SMARTiView protein in SMART
SM00228 PDZ, 8 hits
SUPFAMiSSF50156 SSF50156, 8 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 8 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

H0YGQ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VMLQNVSKES FERTINIAKG NSSLGMTVSA NKDGLGMIVR SIIHGGAISR
60 70 80 90 100
DGRIAIGDCI LSINEESTIS VTNAQARAML RRHSLIGPDI KITYVPAEHL
110 120 130 140 150
EEFKISLGQQ SGRVMALDIF SSYTGRDIPE LPEREEGEGE ESELQNTAYS
160 170 180 190 200
NWNQPRRVEL WREPSKSLGI SIVGGRGMGS RLSNGEVMRG IFIKHVLEDS
210 220 230 240 250
PAGKNGTLKP GDRIVEAPSQ SESEPEKAPL CSVPPPPPSA FAEMGSDHTQ
260 270 280 290 300
SSASKISQDV DKEDEFGYSW KNIRERYGTL TGELHMIELE KGHSGLGLSL
310 320 330 340 350
AGNKDRSRMS VFIVGIDPNG AAGKDGRLQI ADELLEINGQ ILYGRSHQNA
360 370 380 390 400
SSIIKCAPSK VKIIFIRNKD AVNQMAVCPG NAVEPLPSNS ENLQNKETEP
410 420 430 440 450
TVTTSDAAVD LSSFKNVQHL ELPKDQGGLG IAISEEDTLS GVIIKSLTEH
460 470 480 490 500
GVAATDGRLK VGDQILAVDD EIVVGYPIEK FISLLKTAKM TVKLTIHAEN
510 520 530 540 550
PDSQAVPSAA GAASGEKKNS SQSLMVPQSG SPEPESIRNT SRSSTPAIFA
560 570 580 590 600
SDPATCPIIP GCETTIEISK GRTGLGLSIV GGSDTLLGAI IIHEVYEEGA
610 620 630 640 650
ACKDGRLWAG DQILEVNGID LRKATHDEAI NVLRQTPQRV RLTLYRDEAP
660 670 680 690 700
YKEEEVCDTL TIELQKKPGK GLGLSIVGKR NDTGVFVSDI VKGGIADADG
710 720 730 740 750
RLMQGDQILM VNGEDVRNAT QEAVAALLKC SLGTVTLEVG RIKAGPFHSE
760 770 780 790 800
RRPSQSSQVS EGSLSSFTFP LSGSSTSESL ESSSKKNALA SEIQGLRTVE
810 820 830 840 850
MKKGPTDSLG ISIAGGVGSP LGDVPIFIAM MHPTGVAAQT QKLRVGDRIV
860 870 880 890 900
TICGTSTEGM THTQAVNLLK NASGSIEMQV VAGGDVSVVT GHQQEPASSS
910 920 930 940 950
LSFTGLTSSS IFQDDLGPPQ CKSITLERGP DGLGFSIVGG YGSPHGDLPI
960 970 980 990 1000
YVKTVFAKGA ASEDGRLKRG DQIIAVNGQS LEGVTHEEAV AILKRTKGTV

TLMVLS
Length:1,006
Mass (Da):106,759
Last modified:February 22, 2012 - v1
Checksum:i9831C8D09ACB99CF
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75970MPDZ_HUMAN
Multiple PDZ domain protein
MPDZ MUPP1
2,070Annotation score:
F5H1U9F5H1U9_HUMAN
Multiple PDZ domain protein
MPDZ
2,084Annotation score:
B7ZB24B7ZB24_HUMAN
cDNA, FLJ79388, highly similar to M...
MPDZ
929Annotation score:
H0YH70H0YH70_HUMAN
Multiple PDZ domain protein
MPDZ
95Annotation score:
F8WDQ8F8WDQ8_HUMAN
Multiple PDZ domain protein
MPDZ
191Annotation score:
H3BM19H3BM19_HUMAN
Multiple PDZ domain protein
MPDZ
79Annotation score:
A0A075B6R8A0A075B6R8_HUMAN
Multiple PDZ domain protein
MPDZ
611Annotation score:
F5H8D6F5H8D6_HUMAN
Multiple PDZ domain protein
MPDZ
128Annotation score:
H0YFZ6H0YFZ6_HUMAN
Multiple PDZ domain protein
MPDZ
30Annotation score:
H0YF96H0YF96_HUMAN
Multiple PDZ domain protein
MPDZ
34Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL161449 Genomic DNA No translation available.
AL162386 Genomic DNA No translation available.
AL353639 Genomic DNA No translation available.
KF458899 Genomic DNA No translation available.
KF458902 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000545857; ENSP00000444230; ENSG00000107186
UCSCiuc064sdo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL161449 Genomic DNA No translation available.
AL162386 Genomic DNA No translation available.
AL353639 Genomic DNA No translation available.
KF458899 Genomic DNA No translation available.
KF458902 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YGQ3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0YGQ3
MaxQBiH0YGQ3
PeptideAtlasiH0YGQ3
PRIDEiH0YGQ3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000545857; ENSP00000444230; ENSG00000107186
UCSCiuc064sdo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000107186.16
HGNCiHGNC:7208 MPDZ
OpenTargetsiENSG00000107186
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3528 Eukaryota
ENOG4110362 LUCA
GeneTreeiENSGT00760000119017

Miscellaneous databases

ChiTaRSiMPDZ human

Gene expression databases

BgeeiENSG00000107186 Expressed in 224 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0YGQ3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR032078 MPDZ
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF16667 MPDZ_u10, 1 hit
PF00595 PDZ, 7 hits
SMARTiView protein in SMART
SM00228 PDZ, 8 hits
SUPFAMiSSF50156 SSF50156, 8 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 8 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0YGQ3_HUMAN
AccessioniPrimary (citable) accession number: H0YGQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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