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Protein
Submitted name:

Nucleolar GTP-binding protein 2

Gene

GNL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleolar GTP-binding protein 2Imported
Gene namesi
Name:GNL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000134697.12
HGNCiHGNC:29925 GNL2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei91 – 118HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134697

PTM / Processingi

Proteomic databases

EPDiH0YG10
PeptideAtlasiH0YG10
PRIDEiH0YG10

Expressioni

Gene expression databases

BgeeiENSG00000134697 Expressed in 228 organ(s), highest expression level in testis
ExpressionAtlasiH0YG10 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YG10
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 220CP-type GInterPro annotationAdd BLAST220

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2423 Eukaryota
COG1161 LUCA
GeneTreeiENSGT00810000125524

Family and domain databases

InterProiView protein in InterPro
IPR030378 G_CP_dom
IPR006073 GTP_binding_domain
IPR024929 NOG2
IPR027417 P-loop_NTPase
PANTHERiPTHR11089:SF9 PTHR11089:SF9, 2 hits
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51721 G_CP, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

H0YG10-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XDVVVQVLDA RDPMGTRSPH IETYLKKEKP WKHLIFVLNK CDLVPTWATK
60 70 80 90 100
RWVAVLSQDY PTLAFHASLT NPFGKGAFIQ LLRQFGKPWH LTFHALLGFP
110 120 130 140 150
GLLCILCPWS PCSFYVLWLE RALPKFKLQI PGQTSAPEGS RGTRLPYQIL
160 170 180 190 200
KASCSLHTDK KQISVGFIGY PNVGKSSVIN TLRSKKVCNV APIAGETKVW
210 220 230
QYITLMRRIF LIDCPGVVYP SEDSETDIVL KGV
Length:233
Mass (Da):26,235
Last modified:October 29, 2014 - v2
Checksum:i38CBC16E5724A2BB
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q13823NOG2_HUMAN
Nucleolar GTP-binding protein 2
GNL2 NGP1
731Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei233Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL034379 Genomic DNA No translation available.
AL513220 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000538069; ENSP00000441288; ENSG00000134697
UCSCiuc057ewq.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL034379 Genomic DNA No translation available.
AL513220 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YG10
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0YG10
PeptideAtlasiH0YG10
PRIDEiH0YG10

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000538069; ENSP00000441288; ENSG00000134697
UCSCiuc057ewq.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000134697.12
HGNCiHGNC:29925 GNL2
OpenTargetsiENSG00000134697
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2423 Eukaryota
COG1161 LUCA
GeneTreeiENSGT00810000125524

Miscellaneous databases

ChiTaRSiGNL2 human

Gene expression databases

BgeeiENSG00000134697 Expressed in 228 organ(s), highest expression level in testis
ExpressionAtlasiH0YG10 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR030378 G_CP_dom
IPR006073 GTP_binding_domain
IPR024929 NOG2
IPR027417 P-loop_NTPase
PANTHERiPTHR11089:SF9 PTHR11089:SF9, 2 hits
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51721 G_CP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YG10_HUMAN
AccessioniPrimary (citable) accession number: H0YG10
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: October 29, 2014
Last modified: November 7, 2018
This is version 49 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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