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UniProtKB - H0YFI4 (H0YFI4_HUMAN)
Protein
Submitted name:
Dual-specificity tyrosine-phosphorylation-regulated kinase 4
Gene
DYRK4
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Dual-specificity tyrosine-phosphorylation-regulated kinase 4Imported |
Gene namesi | Name:DYRK4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3095, DYRK4 |
VEuPathDBi | HostDB:ENSG00000010219 |
Expressioni
Gene expression databases
Bgeei | ENSG00000010219, Expressed in left testis and 214 other tissues |
ExpressionAtlasi | H0YFI4, baseline and differential |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 65 – 109 | DisorderedSequence analysisAdd BLAST | 45 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 68 – 83 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 84 – 98 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Phylogenomic databases
GeneTreei | ENSGT00940000159401 |
HOGENOMi | CLU_2066702_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf |
SUPFAMi | SSF56112, SSF56112, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
H0YFI4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XSKGFPKNIT NNRGKKRYPD SKDLTMVLKT YDTSFLDFLR RCLVWEPSLR
60 70 80 90 100
MTPDQALKHA WIHQSRNLKP QPRPQTLRKS NSFFPSETRK DKVQGCHHSS
110 120
RKGTACQITS PSPTVRELIF
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NR20 | DYRK4_HUMAN | Dual specificity tyrosine-phosphory... | DYRK4 | 520 | Annotation score: | ||
A0A0A0MTH5 | A0A0A0MTH5_HUMAN | Dual-specificity kinase | DYRK4 | 634 | Annotation score: | ||
F5GWS4 | F5GWS4_HUMAN | Dual-specificity tyrosine-phosphory... | DYRK4 | 68 | Annotation score: | ||
F5H4X6 | F5H4X6_HUMAN | Dual-specificity tyrosine-phosphory... | DYRK4 | 59 | Annotation score: | ||
F5H3D3 | F5H3D3_HUMAN | Dual-specificity tyrosine-phosphory... | DYRK4 | 43 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005832 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000544671; ENSP00000438769; ENSG00000010219 |
UCSCi | uc058jzv.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005832 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H0YFI4 |
Protocols and materials databases
Antibodypediai | 22291, 293 antibodies from 28 providers |
Genome annotation databases
Ensembli | ENST00000544671; ENSP00000438769; ENSG00000010219 |
UCSCi | uc058jzv.1, human |
Organism-specific databases
HGNCi | HGNC:3095, DYRK4 |
OpenTargetsi | ENSG00000010219 |
VEuPathDBi | HostDB:ENSG00000010219 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159401 |
HOGENOMi | CLU_2066702_0_0_1 |
Miscellaneous databases
ChiTaRSi | DYRK4, human |
Gene expression databases
Bgeei | ENSG00000010219, Expressed in left testis and 214 other tissues |
ExpressionAtlasi | H0YFI4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf |
SUPFAMi | SSF56112, SSF56112, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YFI4_HUMAN | |
Accessioni | H0YFI4Primary (citable) accession number: H0YFI4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | January 19, 2022 | |
This is version 51 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |