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Protein
Submitted name:

Dedicator of cytokinesis protein 10

Gene

DOCK10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dedicator of cytokinesis protein 10Imported
Gene namesi
Name:DOCK10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000135905.18
HGNCiHGNC:23479 DOCK10

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135905

PTM / Processingi

Proteomic databases

MaxQBiH0YFC5
PeptideAtlasiH0YFC5
PRIDEiH0YFC5

Expressioni

Gene expression databases

BgeeiENSG00000135905 Expressed in 192 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0YFC5 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0YFC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 190DHR-2InterPro annotationAdd BLAST190

Sequence similaritiesi

Belongs to the DOCK family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1997 Eukaryota
ENOG410XNVY LUCA
GeneTreeiENSGT00760000119234

Family and domain databases

InterProiView protein in InterPro
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
PANTHERiPTHR23317 PTHR23317, 1 hit
PfamiView protein in Pfam
PF06920 DHR-2, 1 hit
PROSITEiView protein in PROSITE
PS51651 DHR_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H0YFC5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XYDIHRSYLK VAEVVNSEKR LFGRYYRVAF YGQAVGFFEE EEGKEYIYKE
60 70 80 90 100
PKLTGLSEIS QRLLKLYADK FGADNVKIIQ DSNKVNPKDL DPKYAYIQVT
110 120 130 140 150
YVTPFFEEKE IEDRKTDFEM HHNINRFVFE TPFTLSGKKH GGVAEQCKRR
160 170 180 190
TILTTSHLFP YVKKRIQVIS QSSTELNPIE VAIDEMSKKV
Length:190
Mass (Da):22,262
Last modified:February 22, 2012 - v1
Checksum:iF278C9A4387DBFD7
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96BY6DOC10_HUMAN
Dedicator of cytokinesis protein 10
DOCK10 KIAA0694, ZIZ3
2,186Annotation score:
A0A2R8YD85A0A2R8YD85_HUMAN
Dedicator of cytokinesis protein 10
DOCK10
2,199Annotation score:
F8WE73F8WE73_HUMAN
Dedicator of cytokinesis protein 10
DOCK10
142Annotation score:
H7C0I3H7C0I3_HUMAN
Dedicator of cytokinesis protein 10
DOCK10
380Annotation score:
A0A2R8Y5U0A0A2R8Y5U0_HUMAN
Dedicator of cytokinesis protein 10
DOCK10
163Annotation score:
F8WB48F8WB48_HUMAN
Dedicator of cytokinesis protein 10
DOCK10
42Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei190Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011739 Genomic DNA No translation available.
AC017095 Genomic DNA No translation available.
AC093806 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000535663; ENSP00000437947; ENSG00000135905
UCSCiuc061tdo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011739 Genomic DNA No translation available.
AC017095 Genomic DNA No translation available.
AC093806 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YFC5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YFC5
PeptideAtlasiH0YFC5
PRIDEiH0YFC5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535663; ENSP00000437947; ENSG00000135905
UCSCiuc061tdo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000135905.18
HGNCiHGNC:23479 DOCK10
OpenTargetsiENSG00000135905
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1997 Eukaryota
ENOG410XNVY LUCA
GeneTreeiENSGT00760000119234

Miscellaneous databases

ChiTaRSiDOCK10 human

Gene expression databases

BgeeiENSG00000135905 Expressed in 192 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0YFC5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
PANTHERiPTHR23317 PTHR23317, 1 hit
PfamiView protein in Pfam
PF06920 DHR-2, 1 hit
PROSITEiView protein in PROSITE
PS51651 DHR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YFC5_HUMAN
AccessioniPrimary (citable) accession number: H0YFC5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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