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Protein
Submitted name:

Cation-dependent mannose-6-phosphate receptor

Gene

M6PR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Cation-dependent mannose-6-phosphate receptorImported
Gene namesi
Name:M6PRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000003056.7
HGNCiHGNC:6752 M6PR

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000003056

PTM / Processingi

Proteomic databases

MaxQBiH0YF90
PeptideAtlasiH0YF90
PRIDEiH0YF90

Expressioni

Gene expression databases

BgeeiENSG00000003056 Expressed in 234 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiH0YF90 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YF90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK0D Eukaryota
ENOG4111GED LUCA
GeneTreeiENSGT00390000002109

Family and domain databases

InterProiView protein in InterPro
IPR028927 Man-6-P_rcpt
IPR000296 Man-6-P_rcpt_cation_dep
PANTHERiPTHR15071:SF9 PTHR15071:SF9, 1 hit
PfamiView protein in Pfam
PF02157 Man-6-P_recep, 2 hits
PRINTSiPR00715 MAN6PRECEPTR

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.iShow all

H0YF90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LLLLLAVAVR ESWQTEEKTC DLDNFNPVSE ERGKVQDCFY LFEMDSSLAC
60 70 80 90 100
SPEISHLSVG SILLVTFASL VAVYVVGGFL YQRLVVGAKG MEQFPHLAFW
110 120 130 140
QDLGNLVADG CDFVCRSKPR NVPAAYRGVG DDQLGEESEE RDDHLLPM
Length:148
Mass (Da):16,446
Last modified:February 22, 2012 - v1
Checksum:iE77DD3139CE64C2E
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P20645MPRD_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR MPR46, MPRD
277Annotation score:
F5GX30F5GX30_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
191Annotation score:
F5GXU0F5GXU0_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
109Annotation score:
F5GXE0F5GXE0_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
92Annotation score:
F5H883F5H883_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
133Annotation score:
H0YGT2H0YGT2_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
122Annotation score:
H0YFY9H0YFY9_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
85Annotation score:
H0YGE9H0YGE9_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
104Annotation score:
H0YFL0H0YFL0_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
96Annotation score:
F5H4U1F5H4U1_HUMAN
Cation-dependent mannose-6-phosphat...
M6PR
25Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006581 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000543704; ENSP00000437595; ENSG00000003056
UCSCiuc058kyy.1 human

Similar proteinsi

Entry informationi

Entry nameiH0YF90_HUMAN
AccessioniPrimary (citable) accession number: H0YF90
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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