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Protein
Submitted name:

Breast cancer type 2 susceptibility protein

Gene

BRCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Breast cancer type 2 susceptibility proteinImported
Gene namesi
Name:BRCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000139618.14
HGNCiHGNC:1101 BRCA2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000139618

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YE37
PRIDEiH0YE37

Expressioni

Gene expression databases

BgeeiENSG00000139618
ExpressionAtlasiH0YE37 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YE37
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 156BRCA-2_OB3InterPro annotationAdd BLAST119

Phylogenomic databases

GeneTreeiENSGT00390000003602

Family and domain databases

InterProiView protein in InterPro
IPR015525 BRCA2
IPR015188 BRCA2_OB_3
IPR012340 NA-bd_OB-fold
PANTHERiPTHR11289 PTHR11289, 1 hit
PfamiView protein in Pfam
PF09104 BRCA-2_OB3, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit

Sequencei

Sequence statusi: Fragment.

H0YE37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XSKSKSERAN IQLAATKKTQ YQQLPVSDEI LFQIYQPREP LHFSKFLDPD
60 70 80 90 100
FQPSCSEVDL IGFVVSVVKK TGLAPFVYLS DECYNLLAIK FWIDLNEDII
110 120 130 140 150
KPHMLIAASN LQWRPESKSG LLTLFAGDFS VFSASPKEGH FQETFNKMKN
160 170 180
TVERQSLALS PPGWSTIAQS RITAVSASWA QAILVP
Length:186
Mass (Da):20,864
Last modified:February 22, 2012 - v1
Checksum:iE6EEA549E0637A0E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137247 Genomic DNA No translation available.
AL445212 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000470094; ENSP00000434898; ENSG00000139618
UCSCiuc058wfx.1 human

Similar proteinsi

Entry informationi

Entry nameiH0YE37_HUMAN
AccessioniPrimary (citable) accession number: H0YE37
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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