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UniProtKB - H0YDW8 (H0YDW8_HUMAN)
Protein
Submitted name:
Granulysin
Gene
GNLY
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: GranulysinImported |
Gene namesi | Name:GNLYImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4414, GNLY |
VEuPathDBi | HostDB:ENSG00000115523 |
PTM / Processingi
Keywords - PTMi
Disulfide bondARBA annotationProteomic databases
PeptideAtlasi | H0YDW8 |
PRIDEi | H0YDW8 |
ProteomicsDBi | 37537 |
Expressioni
Gene expression databases
Bgeei | ENSG00000115523, Expressed in granulocyte and 153 other tissues |
ExpressionAtlasi | H0YDW8, baseline and differential |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 109 | Saposin B-typeInterPro annotationAdd BLAST | 81 |
Phylogenomic databases
GeneTreei | ENSGT00390000002975 |
HOGENOMi | CLU_1457641_0_0_1 |
PhylomeDBi | H0YDW8 |
Family and domain databases
InterProi | View protein in InterPro IPR038847, Granulysin-like IPR011001, Saposin-like IPR008139, SaposinB_dom |
PANTHERi | PTHR15541, PTHR15541, 1 hit |
SMARTi | View protein in SMART SM00741, SapB, 1 hit |
SUPFAMi | SSF47862, SSF47862, 1 hit |
PROSITEi | View protein in PROSITE PS50015, SAP_B, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
H0YDW8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XHLRDEEKSC PCLAQEGPQG DLLTKTQELG RDYRTCLTIV QKLKKMVDKP
60 70 80 90 100
TQRSVSNAAT RVCRTGRSRW RDVCRNFMRR YQSRVTQGLV AGETAQQICE
110 120 130 140 150
DLRLCIPSTG PTTCSGCRLA SRMCLWVPSE PSHLVLWKKH RLLSSDPGNL
160 170 180
SNLCRLLASS IQNPLSSLPP LTPSAVLPSH ENKVSSK
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP22749 | GNLY_HUMAN | Granulysin | GNLY LAG2, NKG5, TLA519 | 145 | Annotation score: | ||
B4E3H9 | B4E3H9_HUMAN | Granulysin | GNLY | 172 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 187 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012454 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000526018; ENSP00000434467; ENSG00000115523 |
UCSCi | uc061ljq.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012454 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H0YDW8 |
PRIDEi | H0YDW8 |
ProteomicsDBi | 37537 |
Protocols and materials databases
Antibodypediai | 31957, 260 antibodies from 27 providers |
Genome annotation databases
Ensembli | ENST00000526018; ENSP00000434467; ENSG00000115523 |
UCSCi | uc061ljq.1, human |
Organism-specific databases
HGNCi | HGNC:4414, GNLY |
OpenTargetsi | ENSG00000115523 |
VEuPathDBi | HostDB:ENSG00000115523 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000002975 |
HOGENOMi | CLU_1457641_0_0_1 |
PhylomeDBi | H0YDW8 |
Miscellaneous databases
ChiTaRSi | GNLY, human |
Gene expression databases
Bgeei | ENSG00000115523, Expressed in granulocyte and 153 other tissues |
ExpressionAtlasi | H0YDW8, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR038847, Granulysin-like IPR011001, Saposin-like IPR008139, SaposinB_dom |
PANTHERi | PTHR15541, PTHR15541, 1 hit |
SMARTi | View protein in SMART SM00741, SapB, 1 hit |
SUPFAMi | SSF47862, SSF47862, 1 hit |
PROSITEi | View protein in PROSITE PS50015, SAP_B, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YDW8_HUMAN | |
Accessioni | H0YDW8Primary (citable) accession number: H0YDW8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | January 19, 2022 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |